Search Results - "Shinosaki, Toshihiro"
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Genetic Variations in the Gene Encoding ELMO1 Are Associated With Susceptibility to Diabetic Nephropathy
Published in Diabetes (New York, N.Y.) (01-04-2005)“…Genetic Variations in the Gene Encoding ELMO1 Are Associated With Susceptibility to Diabetic Nephropathy Atsuyuki Shimazaki 1 , Yoshihiro Kawamura 1 , Akio…”
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Intussusceptive capillary growth is required for glomerular repair in rat Thy-1.1 nephritis
Published in Kidney international (01-04-2003)“…Intussusceptive capillary growth is required for glomerular repair in rat Thy-1.1 nephritis. Injection of anti-Thy-1.1 antibodies to rats causes mesangiolysis,…”
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Mechanisms underlying the ameliorative property of lisinopril in progressive mesangioproliferative nephritis
Published in Nephron (2015) (01-08-2002)“…The present study was performed to clarify the mechanism underlying the beneficial effects of lisinopril on chronic glomerulonephritis. Chronic…”
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4
Glomerular epithelial cell injury accelerates the progression of antibody-induced mesangial proliferative nephritis
Published in Experimental nephrology (01-01-2002)“…Anti-Thy-1.1 antibody induces mesangioproliferative glomerulonephritis; however, the mesangial lesion is spontaneously recovered to the normal feature…”
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A selective peroxisome proliferator-activated receptor δ agonist PYPEP suppresses atherosclerosis in association with improvement of the serum lipoprotein profiles in human apolipoprotein B100 and cholesteryl ester transfer protein double transgenic mice
Published in Metabolism, clinical and experimental (2016)“…Abstract Objective Although peroxisome proliferator-activated receptor (PPAR) δ agonists have been shown to improve the serum lipoprotein profiles in humans,…”
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Pharmacological evaluation of adipose dysfunction via 11β-hydroxysteroid dehydrogenase type 1 in the development of diabetes in diet-induced obese mice with cortisone pellet implantation
Published in The Journal of pharmacology and experimental therapeutics (01-04-2014)“…Signals from intracellular glucocorticoids (GCs) via 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) in adipose tissues have been reported to serve as…”
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Genetic variations in the gene encoding ELM01 are associated with susceptibility to diabetic nephropathy
Published in Diabetes (New York, N.Y.) (01-04-2005)Get full text
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8
Irbesartan enhances GLUT4 translocation and glucose transport in skeletal muscle cells
Published in European journal of pharmacology (15-12-2010)“…Irbesartan, an angiotensin II type 1 receptor blocker has been reported to alleviate metabolic disorder in animal studies and human clinical trials. Although…”
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Cortactin interacts with podocalyxin and mediates morphological change of podocytes through its phosphorylation
Published in Nephron. Experimental nephrology (01-01-2009)“…Morphological change of podocytes is closely correlated with the development of proteinuria. Podocalyxin is a major sialoglycoprotein of the podocytes and is…”
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Renoprotective Action of a Matrix Metalloproteinase Inhibitor in Progressive Mesangioproliferative Nephritis
Published in Nephron extra (26-05-2012)“…Background/Aim: Matrix metalloproteinases (MMPs) play pivotal roles in extracellular matrix turnover and are involved in chronic kidney disease. The…”
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Hyperuricemia Induced by the Uricosuric Drug Probenecid in Rats
Published in Japanese Journal of Pharmacology (1991)“…Stimulation of uric acid production by the well-known uricosuric drug probenecid was studied using potassium oxonate-treated rats and eviscerated rats…”
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Dual Effects of Lisinopril on Puromycin Aminonucleoside Nephrosis in Unilaterally Nephrectomized Rats
Published in Japanese Journal of Pharmacology (1997)“…The therapeutic effects of angiotensin converting enzyme inhibitor, lisinopril, on puromycin aminonucleoside (PAN)-induced nephrosis were investigated using…”
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13
Involvement of Dipeptidyl Peptidase IV in Immune Complex–Mediated Glomerulonephritis
Published in Laboratory investigation (01-04-2002)“…Dipeptidyl peptidase IV (DPPIV) is widely expressed in many tissues; however, its precise biological function is poorly understood. One of its possible…”
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14
Circadian Rhythm of Plasma Uric Acid and Handling Stress-Induced Hyperuricemia in Conscious Cebus Monkeys
Published in Japanese Journal of Pharmacology (1992)“…An apparent circadian rhythm of plasma uric acid and the effect of handling stress on plasma uric acid level in conscious cebus monkeys were demonstrated. The…”
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Dual Effects of Lisinopril on Puromycin Aminonucleoside Nephrosis in Unilaterally Nephrectomized Rats
Published in Japanese journal of pharmacology (1997)“…The therapeutic effects of angiotensin converting enzyme inhibitor, lisinopril, on puromycin aminonucleoside (PAN)-induced nephrosis were investigated using…”
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16
Altered expression of matrix-related molecules in the development of chronic Thy1.1 nephritis
Published in Nephron. Experimental nephrology (01-01-2006)“…Matrix production and degradation are critically important in chronic nephritis. Our aim was to investigate the precise expression of matrix-related molecules…”
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Effects of a potent ACEI, lisinopril, on mesangial proliferative glomerulonephritis
Published in Japanese Journal of Pharmacology (1995)“…「Purposes」 We established a monoclonal antibody against rat mesangial cell. This antibody called E30 causes massive proteinuria followed by mesangial cell…”
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18
Circadian Rhythm of Plasma Uric Acid and Handling Stress-Induced Hyperuricemia in Conscious Cebus Monkeys
Published in Japanese journal of pharmacology (1992)“…An apparent circadian rhythm of plasma uric acid and the effect of handling stress on plasma uric acid level in conscious cebus monkeys were demonstrated. The…”
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19
A New Uricosuric Diuretic, S-8666, in Rats and Chimpanzees
Published in Japanese journal of pharmacology (1987)“…5 Dimethylsulfamoyl-6, 7-dichloro-2, 3-dihydrobenzofuran-2-carboxylic acid (S-8666) was studied as a possible new uricosuric diuretic agent using rats and…”
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140 STOP-FLOW STUDIES ON TUBULAR TRANSPORT OF URIC ACID IN RATS
Published in Pediatric research (01-07-1988)Get full text
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