Search Results - "Shinohara, T"
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SpaGCN: Integrating gene expression, spatial location and histology to identify spatial domains and spatially variable genes by graph convolutional network
Published in Nature methods (01-11-2021)“…Recent advances in spatially resolved transcriptomics (SRT) technologies have enabled comprehensive characterization of gene expression patterns in the context…”
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Interpreting support vector machine models for multivariate group wise analysis in neuroimaging
Published in Medical image analysis (01-08-2015)“…•Support vector machines (SVM) use multivariate imaging information for diagnosis.•Approximate SVM permutation tests for population statistics.•Improved…”
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Harmonization of cortical thickness measurements across scanners and sites
Published in NeuroImage (Orlando, Fla.) (15-02-2018)“…With the proliferation of multi-site neuroimaging studies, there is a greater need for handling non-biological variance introduced by differences in MRI…”
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4
Statistical harmonization corrects site effects in functional connectivity measurements from multi‐site fMRI data
Published in Human brain mapping (01-11-2018)“…Acquiring resting‐state functional magnetic resonance imaging (fMRI) datasets at multiple MRI scanners and clinical sites can improve statistical power and…”
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Harmonization of multi-site diffusion tensor imaging data
Published in NeuroImage (Orlando, Fla.) (01-11-2017)“…Diffusion tensor imaging (DTI) is a well-established magnetic resonance imaging (MRI) technique used for studying microstructural changes in the white matter…”
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Benchmarking of participant-level confound regression strategies for the control of motion artifact in studies of functional connectivity
Published in NeuroImage (Orlando, Fla.) (01-07-2017)“…Since initial reports regarding the impact of motion artifact on measures of functional connectivity, there has been a proliferation of participant-level…”
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Longitudinal ComBat: A method for harmonizing longitudinal multi-scanner imaging data
Published in NeuroImage (Orlando, Fla.) (15-10-2020)“…While aggregation of neuroimaging datasets from multiple sites and scanners can yield increased statistical power, it also presents challenges due to…”
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Large-scale Radiomic Profiling of Recurrent Glioblastoma Identifies an Imaging Predictor for Stratifying Anti-Angiogenic Treatment Response
Published in Clinical cancer research (01-12-2016)“…Antiangiogenic treatment with bevacizumab, a mAb to the VEGF, is the single most widely used therapeutic agent for patients with recurrent glioblastoma. A…”
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Linked dimensions of psychopathology and connectivity in functional brain networks
Published in Nature communications (01-08-2018)“…Neurobiological abnormalities associated with psychiatric disorders do not map well to existing diagnostic categories. High co-morbidity suggests dimensional…”
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10
Multidimensional brain-age prediction reveals altered brain developmental trajectory in psychiatric disorders
Published in Cerebral cortex (New York, N.Y. 1991) (09-11-2022)“…Brain-age prediction has emerged as a novel approach for studying brain development. However, brain regions change in different ways and at different rates…”
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Two distinct neuroanatomical subtypes of schizophrenia revealed using machine learning
Published in Brain (London, England : 1878) (01-03-2020)“…Neurobiological heterogeneity in schizophrenia is poorly understood and confounds current analyses. We investigated neuroanatomical subtypes in a…”
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Image harmonization: A review of statistical and deep learning methods for removing batch effects and evaluation metrics for effective harmonization
Published in NeuroImage (Orlando, Fla.) (01-07-2023)“…•Batch effects introduce significant confounding in multi-batch neuroimaging data.•Removal of batch effects is critical for reproducibility and…”
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13
Modular Segregation of Structural Brain Networks Supports the Development of Executive Function in Youth
Published in Current biology (05-06-2017)“…The human brain is organized into large-scale functional modules that have been shown to evolve in childhood and adolescence. However, it remains unknown…”
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Childhood trauma history is linked to abnormal brain connectivity in major depression
Published in Proceedings of the National Academy of Sciences - PNAS (23-04-2019)“…Patients with major depressive disorder (MDD) present with heterogeneous symptom profiles, while neurobiological mechanisms are still largely unknown. Brain…”
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Spatial distribution of interictal spikes fluctuates over time and localizes seizure onset
Published in Brain (London, England : 1878) (01-02-2020)“…The location of interictal spikes is used to aid surgical planning in patients with medically refractory epilepsy; however, their spatial and temporal dynamics…”
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Normative brain size variation and brain shape diversity in humans
Published in Science (American Association for the Advancement of Science) (15-06-2018)“…Brain size variation over primate evolution and human development is associated with shifts in the proportions of different brain regions. Individual brain…”
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The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative
Published in Nature reviews. Neurology (01-12-2016)“…The central vein sign (CVS) has been proposed as a novel MRI biomarker to improve the accuracy and speed of multiple sclerosis (MS) diagnosis. This Consensus…”
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Generalized ComBat harmonization methods for radiomic features with multi-modal distributions and multiple batch effects
Published in Scientific reports (16-03-2022)“…Radiomic features have a wide range of clinical applications, but variability due to image acquisition factors can affect their performance. The harmonization…”
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Treatment pathway of bone sarcoma in children, adolescents, and young adults
Published in Cancer (15-06-2017)“…When pediatric, adolescent, and young adult patients present with a bone sarcoma, treatment decisions, especially after relapse, are complex and require a…”
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Removing inter-subject technical variability in magnetic resonance imaging studies
Published in NeuroImage (Orlando, Fla.) (15-05-2016)“…Magnetic resonance imaging (MRI) intensities are acquired in arbitrary units, making scans non-comparable across sites and between subjects. Intensity…”
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