Search Results - "Shinoda, Koji"
-
1
Brain gray matter astroglia-specific connexin 43 ablation attenuates spinal cord inflammatory demyelination
Published in Journal of neuroinflammation (05-06-2021)“…Brain astroglia are activated preceding the onset of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). We…”
Get full text
Journal Article -
2
HLA genotype and cortical lesions: Response to the letter from Spencer et al
Published in Multiple sclerosis (01-05-2018)Get full text
Journal Article -
3
HLA-DRB104:05 allele is associated with intracortical lesions on three-dimensional double inversion recovery images in Japanese patients with multiple sclerosis
Published in Multiple sclerosis (01-05-2018)“…Background: Cortical lesions (CLs) frequently observed in Caucasian patients with multiple sclerosis (MS) contribute to disability. However, it remains unclear…”
Get full text
Journal Article -
4
Immune aging in multiple sclerosis is characterized by abnormal CD4 T cell activation and increased frequencies of cytotoxic CD4 T cells with advancing age
Published in EBioMedicine (01-08-2022)“…Immunosenescence (ISC) describes age-related changes in immune-system composition and function. Multiple sclerosis (MS) is a lifelong inflammatory condition…”
Get full text
Journal Article -
5
Long-term use of interferon-β in multiple sclerosis increases Vδ1 - Vδ2 - Vγ9 - γδ T cells that are associated with a better outcome
Published in Journal of neuroinflammation (13-09-2019)“…We previously reported that Vδ2 Vγ9 γδ T cells were significantly decreased in multiple sclerosis (MS) patients without disease-modifying therapies (untreated…”
Get full text
Journal Article -
6
Contribution of cortical lesions to cognitive impairment in Japanese patients with multiple sclerosis
Published in Scientific reports (23-03-2020)“…Cortical lesions (CLs) have a low prevalence and are associated with physical disabilities in Japanese patients with multiple sclerosis (MS). However, the…”
Get full text
Journal Article -
7
A comparison of brain magnetic resonance imaging lesions in multiple sclerosis by race with reference to disability progression
Published in Journal of neuroinflammation (05-09-2018)“…We compared the magnetic resonance imaging (MRI) features between Japanese and Caucasian patients with multiple sclerosis (MS), and identified the…”
Get full text
Journal Article -
8
Environmental risk factors for multiple sclerosis in Japanese people
Published in Multiple sclerosis and related disorders (01-02-2020)“…•Active and passive smoking are risk factors for Japanese MS, exacerbating disability.•Longer sunlight exposure in early childhood is a protective factor for…”
Get full text
Journal Article -
9
A case of overlapping adult‐onset linear scleroderma and Parry‐Romberg syndrome presenting with widespread ipsilateral neurogenic involvement
Published in Neuropathology (01-02-2020)“…Linear scleroderma is a variant of localized scleroderma. We report a 43‐year‐old woman who had developed left arm weakness and linear scleroderma on her back…”
Get full text
Journal Article -
10
Association of Decreased Percentage of Vδ2 + Vγ9 + γδ T Cells With Disease Severity in Multiple Sclerosis
Published in Frontiers in immunology (10-04-2018)“…We recently reported that deletion-type copy number variations of the T cell receptor (TCR) γ, α, and δ genes greatly enhanced susceptibility to multiple…”
Get full text
Journal Article -
11
CD30 ligand is a new therapeutic target for central nervous system autoimmunity
Published in Journal of autoimmunity (01-02-2015)“…Abstract The CD30 ligand (CD30L)/CD30 axis plays a critical role in Th1 and Th17 cell differentiation. However, the role in the pathogenesis of central nervous…”
Get full text
Journal Article -
12
CD30 ligand could be a new therapeutic target for central nervous system autoimmunity
Published in Clinical & experimental neuroimmunology (01-05-2015)Get full text
Journal Article -
13
Creutzfeldt–Jakob disease‐like diffusion‐weighted imaging hyperintensity paralleled with neuropsychiatric symptoms in a patient with limbic encephalitis associated with anti‐voltage‐gated potassium channel complex antibodies
Published in Clinical & experimental neuroimmunology (01-08-2019)“…In this report, we describe a case of a 58‐year‐old man with limbic encephalitis associated with anti‐voltage‐gated potassium channel complex antibodies…”
Get full text
Journal Article -
14
Peripheral blood T cell subset characteristics of multiple sclerosis in remission phase correlate with annualized relapse rates
Published in Clinical & experimental neuroimmunology (01-11-2016)“…Abstract Objective A large number of disease‐modifying drugs are available for multiple sclerosis ( MS ); however, there is no established biomarker to predict…”
Get full text
Journal Article -
15
内頚動脈急性閉塞に対する経静脈的血栓溶解療法中に対側中大脳動脈閉塞を来し,両側血栓回収術を行った1例
Published in 脳卒中 (2022)“…【緒言】両側中大脳動脈(MCA)の急性閉塞症は稀で,予後は悪い.両側MCA急性閉塞症に対し両側の血栓回収術を施行した症例を報告する.【症例】87歳,男性.初診時 JCS II-10,重度左片麻痺,NIHSS…”
Get full text
Journal Article -
16
Clinical Application of a New Compact Computed Tomography System for Evaluating the Outcome of Regenerative Therapy: A Case Report
Published in Journal of periodontology (1970) (01-05-2001)“…Background: The limitations of conventional 2‐dimensional (2‐D) radiographs have been emphasized in many studies. Because the image is a 2‐D map of the…”
Get full text
Journal Article -
17
Early preferential repopulation of anti-inflammatory B cells following an initial treatment of ocrelizumab in patients with multiple sclerosis (4770)
Published in Neurology (14-04-2020)“…Abstract only…”
Get full text
Journal Article -
18
B Cells Selectively Induce CD8+ MAIT Cell Effector Functions: Implications for Multiple Sclerosis (5355)
Published in Neurology (14-04-2020)“…Abstract only…”
Get full text
Journal Article -
19
Peripheral neuropathy, myelopathy, cerebellar ataxia, and subclinical optic neuropathy associated with copper deficiency occurring 23 years after total gastrectomy
Published in Rinshō shinkeigaku (01-06-2011)“…We report a 61-year-old man with slowly progressive gait disturbance and paresthesia in the lower extremities following a total gastrectomy for gastric cancer…”
Get more information
Journal Article -
20
The 32nd European Committee for Treatment and Research in Multiple Sclerosis
Published in Clinical & experimental neuroimmunology (01-02-2017)Get full text
Journal Article