Search Results - "Shinkai, Soya"
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Dynamic Nucleosome Movement Provides Structural Information of Topological Chromatin Domains in Living Human Cells
Published in PLoS computational biology (01-10-2016)“…The mammalian genome is organized into submegabase-sized chromatin domains (CDs) including topologically associating domains, which have been identified using…”
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PHi-C2: interpreting Hi-C data as the dynamic 3D genome state
Published in Bioinformatics (Oxford, England) (31-10-2022)“…Abstract Summary High-throughput chromosome conformation capture (Hi-C) is a widely used assay for studying the three-dimensional (3D) genome organization…”
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Microrheology for Hi-C Data Reveals the Spectrum of the Dynamic 3D Genome Organization
Published in Biophysical journal (05-05-2020)“…The one-dimensional information of genomic DNA is hierarchically packed inside the eukaryotic cell nucleus and organized in a three-dimensional (3D) space…”
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Condensed but liquid-like domain organization of active chromatin regions in living human cells
Published in Science advances (07-04-2023)“…In eukaryotes, higher-order chromatin organization is spatiotemporally regulated as domains, for various cellular functions. However, their physical nature in…”
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Single-nucleosome imaging reveals steady-state motion of interphase chromatin in living human cells
Published in Science advances (03-06-2022)“…Dynamic chromatin behavior plays a critical role in various genome functions. However, it remains unclear how chromatin behavior changes during interphase,…”
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Bridging the dynamics and organization of chromatin domains by mathematical modeling
Published in Nucleus (Austin, Tex.) (04-07-2017)“…The genome is 3-dimensionally organized in the cell, and the mammalian genome DNA is partitioned into submegabase-sized chromatin domains. Genome functions are…”
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1/f$ Spectrum and 1-Stable Law in One-Dimensional Intermittent Map with Uniform Invariant Measure and Nekhoroshev Stability
Published in Journal of the Physical Society of Japan (01-02-2012)“…We investigate ergodic properties of a one-dimensional intermittent map that has not only an indifferent fixed point but also a singular structure such that a…”
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Toward understanding the dynamic state of 3D genome
Published in Computational and structural biotechnology journal (01-01-2020)“…The three-dimensional (3D) genome organization and its role in biological activities have been investigated for over a decade in the field of cell biology…”
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4D Genome Analysis Using PHi-C2
Published in Methods in molecular biology (Clifton, N.J.) (2025)“…Hi-C methods reveal 3D genome features but lack correspondence to dynamic chromatin behavior. PHi-C2, Python software, addresses this gap by transforming Hi-C…”
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Generalized Lyapunov exponent as a unified characterization of dynamical instabilities
Published in Physical review. E, Statistical, nonlinear, and soft matter physics (30-01-2015)“…The Lyapunov exponent characterizes an exponential growth rate of the difference of nearby orbits. A positive Lyapunov exponent (exponential dynamical…”
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Dissipative Heat Decomposition in Stochastic Energetics: Implication of the Instantaneous Diffusion Coefficient in Nonequilibrium Steady States
Published in Journal of the Physical Society of Japan (01-01-2015)“…We give a decomposition expression for dissipative heat using the instantaneous diffusion coefficient in a nonequilibrium steady state. The dissipative heat…”
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Quantitative Theory of Active Diffusion Trajectories by Instantaneous Diffusion Coefficient
Published in Biophysical journal (27-01-2015)Get full text
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The Lempel-Ziv complexity of non-stationary chaos in infinite ergodic cases
Published in Progress of theoretical physics (01-09-2006)Get full text
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Centromere/kinetochore is assembled through CENP-C oligomerization
Published in Molecular cell (06-07-2023)“…Kinetochore is an essential protein complex required for accurate chromosome segregation. The constitutive centromere-associated network (CCAN), a subcomplex…”
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Distributional Behavior of Time Averages of Non-L1 Observables in One-dimensional Intermittent Maps with Infinite Invariant Measures
Published in Journal of statistical physics (2015)“…In infinite ergodic theory, two distributional limit theorems are well-known. One is characterized by the Mittag-Leffler distribution for time averages of L 1…”
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Single‐molecule tracking of Nanog and Oct4 in living mouse embryonic stem cells uncovers a feedback mechanism of pluripotency maintenance
Published in The EMBO journal (18-09-2023)“…Nanog and Oct4 are core transcription factors that form part of a gene regulatory network to regulate hundreds of target genes for pluripotency maintenance in…”
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1/f Spectrum and 1-Stable Law in One-Dimensional Intermittent Map with Uniform Invariant Measure and Nekhoroshev Stability
Published in Journal of the Physical Society of Japan (01-02-2012)“…We investigate ergodic properties of a one-dimensional intermittent map that has not only an indifferent fixed point but also a singular structure such that a…”
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PHi-C: deciphering Hi-C data into polymer dynamics
Published in NAR genomics and bioinformatics (01-06-2020)“…Abstract Genomes are spatiotemporally organized within the cell nucleus. Genome-wide chromosome conformation capture (Hi-C) technologies have uncovered the 3D…”
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Distributional behavior of time averages of Non-[L.sup.1] observables in one-dimensional intermittent maps with infinite invariant measures
Published in Journal of statistical physics (15-01-2015)“…In infinite ergodic theory, two distributional limit theorems are well-known. One is characterized by the Mittag-Leffler distribution for time averages of…”
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