Search Results - "Shinkai, Fumiko"

Calpain-2 participates in the process of calpain-1 inactivation by Shinkai-Ouchi, Fumiko, Shindo, Mayumi, Doi, Naoko, Hata, Shoji, Ono, Yasuko

“…Calpain-1 and calpain-2 are highly structurally similar isoforms of calpain. The calpains, a family of intracellular cysteine proteases, cleave their…”
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Predictions of Cleavability of Calpain Proteolysis by Quantitative Structure-Activity Relationship Analysis Using Newly Determined Cleavage Sites and Catalytic Efficiencies of an Oligopeptide Array by Shinkai-Ouchi, Fumiko, Koyama, Suguru, Ono, Yasuko, Hata, Shoji, Ojima, Koichi, Shindo, Mayumi, duVerle, David, Ueno, Mika, Kitamura, Fujiko, Doi, Naoko, Takigawa, Ichigaku, Mamitsuka, Hiroshi, Sorimachi, Hiroyuki

“…Calpains are intracellular Ca2+-regulated cysteine proteases that are essential for various cellular functions. Mammalian conventional calpains (calpain-1 and…”
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Hepatitis C virus reveals a novel early control in acute immune response by Arnaud, Noëlla, Dabo, Stéphanie, Akazawa, Daisuke, Fukasawa, Masayoshi, Shinkai-Ouchi, Fumiko, Hugon, Jacques, Wakita, Takaji, Meurs, Eliane F

“…Recognition of viral RNA structures by the intracytosolic RNA helicase RIG-I triggers induction of innate immunity. Efficient induction requires RIG-I…”
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Interorganelle Trafficking of Ceramide Is Regulated by Phosphorylation-dependent Cooperativity between the PH and START Domains of CERT by Kumagai, Keigo, Kawano, Miyuki, Shinkai-Ouchi, Fumiko, Nishijima, Masahiro, Hanada, Kentaro

“…The synthesis and transport of lipids are essential events for membrane biogenesis. However, little is known about how intracellular trafficking of lipids is…”
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Developing fluorescence sensor probe to capture activated muscle-specific calpain-3 (CAPN3) in living muscle cells by Ojima, Koichi, Hata, Shoji, Shinkai-Ouchi, Fumiko, Oe, Mika, Muroya, Susumu, Sorimachi, Hiroyuki, Ono, Yasuko

“…Calpain-3 (CAPN3) is a muscle-specific type of calpain whose protease activity is triggered by Ca Here, we developed CAPN3 sensor probes (SPs) to detect…”
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Mouse Prion Protein (PrP) Segment 100 to 104 Regulates Conversion of PrPC to PrPSc in Prion-Infected Neuroblastoma Cells by Hara, Hideyuki, Okemoto-Nakamura, Yuko, Shinkai-Ouchi, Fumiko, Hanada, Kentaro, Yamakawa, Yoshio, Hagiwara, Ken'ichi

“…Prion diseases are characterized by the replicative propagation of disease-associated forms of prion protein (PrPSc; PrP refers to prion protein). The…”
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Identification and structural analysis of C-terminally truncated collapsin response mediator protein-2 in a murine model of prion diseases by Shinkai-Ouchi, Fumiko, Yamakawa, Yoshio, Hara, Hideyuki, Tobiume, Minoru, Nishijima, Masahiro, Hanada, Kentaro, Hagiwara, Ken'ichi

“…Prion diseases are fatal neurodegenerative disorders that accompany an accumulation of the disease-associated form(s) of prion protein (PrPSc) in the central…”
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Involvement of Creatine Kinase B in Hepatitis C Virus Genome Replication through Interaction with the Viral NS4A Protein by Hara, Hiromichi, Aizaki, Hideki, Matsuda, Mami, Shinkai-Ouchi, Fumiko, Inoue, Yasushi, Murakami, Kyoko, Shoji, Ikuo, Kawakami, Hayato, Matsuura, Yoshiharu, Lai, Michael M C, Miyamura, Tatsuo, Wakita, Takaji, Suzuki, Tetsuro

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Thiol-reactive reagents inhibits intracellular trafficking of human papillomavirus type 16 pseudovirions by binding to cysteine residues of major capsid protein L1 by Ishii, Yoshiyuki, Kondo, Kazunari, Matsumoto, Tamae, Tanaka, Keiko, Shinkai-Ouchi, Fumiko, Hagiwara, Ken'ichi, Kanda, Tadahito

“…A human papillomavirus (HPV) virion is composed of capsid proteins L1 and L2. Several cysteine residues are located on L1 of various HPVs at markedly similar…”
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Cellular vimentin content regulates the protein level of hepatitis C virus core protein and the hepatitis C virus production in cultured cells by Nitahara-Kasahara, Yuko, Fukasawa, Masayoshi, Shinkai-Ouchi, Fumiko, Sato, Shigeko, Suzuki, Tetsuro, Murakami, Kyoko, Wakita, Takaji, Hanada, Kentaro, Miyamura, Tatsuo, Nishijima, Masahiro

“…Abstract Hepatitis C virus (HCV) core protein is essential for virus particle formation. Using HCV core-expressing and non-expressing Huh7 cell lines, Uc39-6…”
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Identification of the Site of Interaction of the 14-3-3 Protein with Phosphorylated Tryptophan Hydroxylase () by Ichimura, Tohru, Uchiyama, Junji, Kunihiro, Okiyuki, Ito, Mitsuki, Horigome, Tsuneyoshi, Omata, Saburo, Shinkai, Fumiko, Kaji, Hiroyuki, Isobe, Toshiaki

“…The 14-3-3 protein family plays a role in a wide variety of cell signaling processes including monoamine synthesis, exocytosis, and cell cycle regulation, but…”
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Erratum to: Poster Session PPo1: Protein Misfolding by Hara, Hideyuki, Okemoto-Nakamura, Yuko, Shinkai-Ouchi, Fumiko, Yamakawa, Yoshio, Hagiwara, Ken'ichi

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A muscle-specific calpain, CAPN3, forms a homotrimer by Hata, Shoji, Doi, Naoko, Shinkai-Ouchi, Fumiko, Ono, Yasuko

“…Calpain-3 (CAPN3), a 94-kDa member of the calpain protease family, is abundant in skeletal muscle. Mutations in the CAPN3 gene cause limb girdle muscular…”
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An eccentric calpain, CAPN3/p94/calpain-3 by Ono, Yasuko, Ojima, Koichi, Shinkai-Ouchi, Fumiko, Hata, Shoji, Sorimachi, Hiroyuki

“…Calpains are Ca2+-regulated proteolytic enzymes that are involved in a variety of biological phenomena. Calpains process substrates by limited proteolysis to…”
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Calpain-3 not only proteolyzes calpain-1 and -2 but also is a substrate for calpain-1 and -2 by Ojima, Koichi, Hata, Shoji, Shinkai-Ouchi, Fumiko, Ono, Yasuko, Muroya, Susumu

“…Calpain is an intracellular cysteine protease that cleaves its specific substrates in a limited region to modulate cellular function. Calpain-1 (C1) and…”
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Mouse prion protein (PrP) segment 100 to 104 regulates conversion of PrP(C) to PrP(Sc) in prion-infected neuroblastoma cells by Hara, Hideyuki, Okemoto-Nakamura, Yuko, Shinkai-Ouchi, Fumiko, Hanada, Kentaro, Yamakawa, Yoshio, Hagiwara, Ken'ichi

“…Prion diseases are characterized by the replicative propagation of disease-associated forms of prion protein (PrP(Sc); PrP refers to prion protein). The…”
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Developing fluorescence sensor probe to capture activated muscle-specific calpain-3 (CAPN3) in living muscle cells by Ojima, Koichi, Hata, Shoji, Shinkai-Ouchi, Fumiko, Oe, Mika, Muroya, Susumu, Sorimachi, Hiroyuki, Ono, Yasuko

“…Calpain-3 (CAPN3) is a muscle specific type of calpain whose protease activity is triggered by Ca2+. Here, we developed CAPN3 sensor probes (SPs) to detect…”
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Characterization of a ligand for receptor protein-tyrosine kinase HTK expressed in immature hematopoietic cells by Sakano, S, Serizawa, R, Inada, T, Iwama, A, Itoh, A, Kato, C, Shimizu, Y, Shinkai, F, Shimizu, R, Kondo, S, Ohno, M, Suda, T

“…HTK is a receptor tyrosine kinase that belongs to the Eph subfamily. An extensive screening using BIAcore system revealed that a colon cancer cell line, C-1,…”
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Fluid shear stress increases the expression of thrombomodulin by cultured human endothelial cells by Takada, Y, Shinkai, F, Kondo, S, Yamamoto, S, Tsuboi, H, Korenaga, R, Ando, J

“…Endothelial cells (ECs) cultured from human umbilical vein were exposed to medium flow in a flow-loading chamber, and changes in thrombomodulin (TM) expression…”
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Mouse Prion Protein (PrP) Segment 100 to 104 Regulates Conversion of PrP C to PrP Sc in Prion-Infected Neuroblastoma Cells by Hara, Hideyuki, Okemoto-Nakamura, Yuko, Shinkai-Ouchi, Fumiko, Hanada, Kentaro, Yamakawa, Yoshio, Hagiwara, Ken'ichi

“…Prion diseases are characterized by the replicative propagation of disease-associated forms of prion protein (PrP Sc ; PrP refers to prion protein). The…”
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