Search Results - "Shindo, Tomoko"

Cell therapy for spinal cord injury by using human iPSC-derived region-specific neural progenitor cells by Kajikawa, Keita, Imaizumi, Kent, Shinozaki, Munehisa, Shibata, Shinsuke, Shindo, Tomoko, Kitagawa, Takahiro, Shibata, Reo, Kamata, Yasuhiro, Kojima, Kota, Nagoshi, Narihito, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki

“…Abstract The transplantation of neural progenitor cells (NPCs) derived from human induced pluripotent stem cells (iPSCs) has beneficial effects on spinal cord…”
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Region- and Cell Type-Specific Facilitation of Synaptic Function at Destination Synapses Induced by Oligodendrocyte Depolarization by Yamazaki, Yoshihiko, Abe, Yoshifumi, Shibata, Shinsuke, Shindo, Tomoko, Fujii, Satoshi, Ikenaka, Kazuhiro, Tanaka, Kenji F

“…The axonal conduction of action potentials affects the absolute time it takes to transmit nerve impulses as well as temporal summation at destination synapses…”
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Modulation by DREADD reveals the therapeutic effect of human iPSC-derived neuronal activity on functional recovery after spinal cord injury by Kitagawa, Takahiro, Nagoshi, Narihito, Kamata, Yasuhiro, Kawai, Momotaro, Ago, Kentaro, Kajikawa, Keita, Shibata, Reo, Sato, Yuta, Imaizumi, Kent, Shindo, Tomoko, Shinozaki, Munehisa, Kohyama, Jun, Shibata, Shinsuke, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki

“…Transplantation of neural stem/progenitor cells (NS/PCs) derived from human induced pluripotent stem cells (hiPSCs) is considered to be a promising therapy for…”
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Administration of C5a Receptor Antagonist Improves the Efficacy of Human Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cell Transplantation in the Acute Phase of Spinal Cord Injury by Shibata, Reo, Nagoshi, Narihito, Kajikawa, Keita, Ito, Shuhei, Shibata, Shinsuke, Shindo, Tomoko, Khazaei, Mohamad, Nori, Satoshi, Kohyama, Jun, Fehlings, Michael G, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki

“…Human-induced pluripotent stem cell-derived neural stem/progenitor cell (hiPSC-NS/PC) transplantation during the acute phase of spinal cord injury (SCI) is not…”
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Rehabilitative Training Enhances Therapeutic Effect of Human-iPSC-Derived Neural Stem/Progenitor Cells Transplantation in Chronic Spinal Cord Injury by Shibata, Takahiro, Tashiro, Syoichi, Shibata, Shinsuke, Shinozaki, Munehisa, Shindo, Tomoko, Hashimoto, Shogo, Kawai, Momotaro, Kitagawa, Takahiro, Ago, Kentaro, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki, Nagoshi, Narihito

“…Cell transplantation therapy using human-induced pluripotent stem cell-derived neural stem/progenitor cells (hiPSC-NS/PCs) is a new therapeutic strategy for…”
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Lem2 and Lnp1 maintain the membrane boundary between the nuclear envelope and endoplasmic reticulum by Hirano, Yasuhiro, Kinugasa, Yasuha, Osakada, Hiroko, Shindo, Tomoko, Kubota, Yoshino, Shibata, Shinsuke, Haraguchi, Tokuko, Hiraoka, Yasushi

“…The nuclear envelope (NE) continues to the endoplasmic reticulum (ER). Proper partitioning of NE and ER is crucial for cellular activity, but the key factors…”
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A robust culture system to generate neural progenitors with gliogenic competence from clinically relevant induced pluripotent stem cells for treatment of spinal cord injury by Kamata, Yasuhiro, Isoda, Miho, Sanosaka, Tsukasa, Shibata, Reo, Ito, Shuhei, Okubo, Toshiki, Shinozaki, Munehisa, Inoue, Mitsuhiro, Koya, Ikuko, Shibata, Shinsuke, Shindo, Tomoko, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki, Nagoshi, Narihito, Kohyama, Jun

“…Cell‐based therapy targeting spinal cord injury (SCI) is an attractive approach to promote functional recovery by replacing damaged tissue. We and other groups…”
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Transfected plasmid DNA is incorporated into the nucleus via nuclear envelope reformation at telophase by Haraguchi, Tokuko, Koujin, Takako, Shindo, Tomoko, Bilir, Şükriye, Osakada, Hiroko, Nishimura, Kohei, Hirano, Yasuhiro, Asakawa, Haruhiko, Mori, Chie, Kobayashi, Shouhei, Okada, Yasushi, Chikashige, Yuji, Fukagawa, Tatsuo, Shibata, Shinsuke, Hiraoka, Yasushi

“…DNA transfection is an important technology in life sciences, wherein nuclear entry of DNA is necessary to express exogenous DNA. Non-viral vectors and their…”
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Large-Area Fluorescence and Electron Microscopic Correlative Imaging With Multibeam Scanning Electron Microscopy by Shibata, Shinsuke, Iseda, Taro, Mitsuhashi, Takayuki, Oka, Atsushi, Shindo, Tomoko, Moritoki, Nobuko, Nagai, Toshihiro, Otsubo, Shinya, Inoue, Takashi, Sasaki, Erika, Akazawa, Chihiro, Takahashi, Takao, Schalek, Richard, Lichtman, Jeff W, Okano, Hideyuki

“…Recent improvements in correlative light and electron microscopy (CLEM) technology have led to dramatic improvements in the ability to observe tissues and…”
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A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer by Shimada, Hiroko, Sato, Yuta, Sasaki, Takashi, Shimozawa, Aki, Imaizumi, Kent, Shindo, Tomoko, Miyao, Sachiyo, Kiyama, Kosuke, Kondo, Takahiro, Shibata, Shinsuke, Ishii, Seiji, Kuromitsu, Junro, Aoyagi, Hirofumi, Ito, Daisuke, Okano, Hideyuki

“…It is known that the human cellular models of Alzheimer’s disease (AD) and tauopathy can only recapitulate the very early stage of the disease. To overcome…”
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Hepatocyte growth factor pretreatment boosts functional recovery after spinal cord injury through human iPSC-derived neural stem/progenitor cell transplantation by Suematsu, Yu, Nagoshi, Narihito, Shinozaki, Munehisa, Kase, Yoshitaka, Saijo, Yusuke, Hashimoto, Shogo, Shibata, Takahiro, Kajikawa, Keita, Kamata, Yasuhiro, Ozaki, Masahiro, Yasutake, Kaori, Shindo, Tomoko, Shibata, Shinsuke, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki

“…BACKGROUNDHuman induced pluripotent stem cell-derived neural stem/progenitor cell (hiPSC-NS/PC)-based cell transplantation has emerged as a groundbreaking…”
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Mutual interaction of neurons and astrocytes derived from iPSCs with APP V717L mutation developed the astrocytic phenotypes of Alzheimer's disease by Supakul, Sopak, Murakami, Rei, Oyama, Chisato, Shindo, Tomoko, Hatakeyama, Yuki, Itsuno, Maika, Bannai, Hiroko, Shibata, Shinsuke, Maeda, Sumihiro, Okano, Hideyuki

“…The development of induced pluripotent stem cells (iPSCs) technology has enabled human cellular disease modeling for inaccessible cell types, such as neural…”
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Novel artificial nerve transplantation of human iPSC-derived neurite bundles enhanced nerve regeneration after peripheral nerve injury by Nishijima, Takayuki, Okuyama, Kentaro, Shibata, Shinsuke, Kimura, Hiroo, Shinozaki, Munehisa, Ouchi, Takehito, Mabuchi, Yo, Ohno, Tatsukuni, Nakayama, Junpei, Hayatsu, Manabu, Uchiyama, Keiko, Shindo, Tomoko, Niiyama, Eri, Toita, Sayaka, Kawada, Jiro, Iwamoto, Takuji, Nakamura, Masaya, Okano, Hideyuki, Nagoshi, Narihito

“…Severe peripheral nerve damage always requires surgical treatment. Autologous nerve transplantation is a standard treatment, but it is not sufficient due to…”
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A non-invasive system to monitor in vivo neural graft activity after spinal cord injury by Ago, Kentaro, Nagoshi, Narihito, Imaizumi, Kent, Kitagawa, Takahiro, Kawai, Momotaro, Kajikawa, Keita, Shibata, Reo, Kamata, Yasuhiro, Kojima, Kota, Shinozaki, Munehisa, Kondo, Takahiro, Iwano, Satoshi, Miyawaki, Atsushi, Ohtsuka, Masanari, Bito, Haruhiko, Kobayashi, Kenta, Shibata, Shinsuke, Shindo, Tomoko, Kohyama, Jun, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki

“…Expectations for neural stem/progenitor cell (NS/PC) transplantation as a treatment for spinal cord injury (SCI) are increasing. However, whether and how…”
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Ovarian dysfunction, obesity and pituitary tumors in female mice following neonatal exposure to low-dose diethylstilbestrol by Ohta, Ryo, Ohmukai, Hideo, Toyoizumi, Tomoyasu, Shindo, Tomoko, Marumo, Hideki, Ono, Hiroshi

“…•Early onset of spontaneous abnormalities in estrus cycle was found in female mice treated with 0.5μg/kg/day of DES. Female mice in the 0.05μg/kg/day of DES or…”
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Development and performance evaluation of a positive reference material for hemolysis testing by Haishima, Yuji, Hasegawa, Chie, Nomura, Yusuke, Kawakami, Tsuyoshi, Yuba, Toshiyasu, Shindo, Tomoko, Sakaguchi, Keisuke, Tanigawa, Takahiro, Inukai, Kaori, Takenouchi, Mika, Isama, Kazuo, Matsuoka, Atsuko, Niimi, Shingo

“…This study deals with the development and performance evaluation of a positive reference material for hemolysis testing, which is used for evaluating the…”
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Delayed reproductive dysfunction in female rats induced by early life exposure to low-dose diethylstilbestrol by Ohta, Ryo, Ohmukai, Hideo, Marumo, Hideki, Shindo, Tomoko, Nagata, Tomoko, Ono, Hiroshi

“…► Early life exposure to low-dose DES caused abnormal estrous cycles, reduced fertility and decreased litter size when the females reached 23 or 24 weeks of…”
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Effective induction of oral anaphylaxis to ovalbumin in mice sensitized by feeding of the antigen with aid of oil emulsion and salicylate by Shindo, Tomoko, Kanazawa, Yukiko, Saito, Yoshiaki, Kojima, Kohichi, Ohsawa, Motoyasu, Teshima, Reiko

“…It is important to evaluate the ability of novel proteins in food crops and products to elicit potentially harmful immunologic responses, including allergic…”
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Effect of butyl benzyl phthalate in Sprague-Dawley rats after gavage administration: a two-generation reproductive study by Nagao, Tetsuji, Ohta, Ryo, Marumo, Hideki, Shindo, Tomoko, Yoshimura, Shinsuke, Ono, Hiroshi

“…Butyl benzyl phthalate (BBP), a plasticizer, has been shown in in vitro studies to be weakly estrogenic, and in in vivo studies to possess testicular toxicity…”
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Similar changes in clinical and pathological parameters in Wistar Kyoto rats after a 13-week dietary intake of canola oil or a fatty acid composition-based interesterified canola oil mimic by Ohara, Naoki, Naito, Yukiko, Kasama, Kikuko, Shindo, Tomoko, Yoshida, Hiromichi, Nagata, Tomoko, Okuyama, Harumi

“…Canola oil (CO) given as a dietary fat deteriorates hypertension-related condition and shortens the life of stroke-prone spontaneously hypertensive rats…”
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