Search Results - "Shinchi, Yusuke"

Accurate expression of PD‐L1/L2 in lung adenocarcinoma cells: A retrospective study by double immunohistochemistry by Shinchi, Yusuke, Komohara, Yoshihiro, Yonemitsu, Kimihiro, Sato, Kensaku, Ohnishi, Koji, Saito, Yoichi, Fujiwara, Yukio, Mori, Takeshi, Shiraishi, Kenji, Ikeda, Koei, Suzuki, Makoto

“…The percentage of programmed death ligand 1 (PD‐L1) positivity in cancer cells, named as the tumor proportion score, is considered to be a predictive biomarker…”
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Classification of PD‐L1 expression in various cancers and macrophages based on immunohistocytological analysis by Saito, Yoichi, Fujiwara, Yukio, Shinchi, Yusuke, Mito, Remi, Miura, Yuji, Yamaguchi, Tomoya, Ikeda, Koei, Urakami, Shinji, Nakashima, Yuta, Sakagami, Takuro, Suzuki, Makoto, Tabata, Yasuhiko, Komohara, Yoshihiro

“…Programmed death (PD)‐1/PD‐ligand 1 (PD‐L1) antibodies have shown an intense clinical effect in some patients with PD‐L1+ tumors, and their applications have…”
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The expression of PD-1 ligand 1 on macrophages and its clinical impacts and mechanisms in lung adenocarcinoma by Shinchi, Yusuke, Ishizuka, Shiho, Komohara, Yoshihiro, Matsubara, Eri, Mito, Remi, Pan, Cheng, Yoshii, Daiki, Yonemitsu, Kimihiro, Fujiwara, Yukio, Ikeda, Koei, Tamada, Koji, Sakagami, Takuro, Suzuki, Makoto

“…Programmed cell death-1 (PD-1) and PD-1 ligand 1 (PD-L1) are target molecules for immunotherapy in non-small cell lung cancer. PD-L1 is expressed not only in…”
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CD163‐positive cancer cells are a predictor of a worse clinical course in lung adenocarcinoma by Matsubara, Eri, Komohara, Yoshihiro, Shinchi, Yusuke, Mito, Remi, Fujiwara, Yukio, Ikeda, Koei, Shima, Toshiyuki, Shimoda, Masayuki, Kanai, Yae, Sakagami, Takuro, Suzuki, Makoto

“…CD163 is one of the scavenger receptors expressed on macrophages. However, several immunohistochemical studies have demonstrated that CD163 is also detected on…”
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PD-L2 overexpression on tumor-associated macrophages is one of the predictors for better prognosis in lung adenocarcinoma by Matsubara, Eri, Shinchi, Yusuke, Komohara, Yoshihiro, Yano, Hiromu, Pan, Cheng, Fujiwara, Yukio, Ikeda, Koei, Suzuki, Makoto

“…Immunotherapies that target programmed cell death protein 1 (PD-1) signals are standard therapies for advanced-stage lung cancer, and the expression of…”
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Soluble Factors Involved in Cancer Cell–Macrophage Interaction Promote Breast Cancer Growth by Yonemitsu, Kimihiro, Miyasato, Yuko, Shiota, Takuya, Shinchi, Yusuke, Fujiwara, Yukio, Hosaka, Seiji, Yamamoto, Yutaka, Komohara, Yoshihiro

“…Background/Aim: Recent studies have indicated the clinical significance of tumor-associated macrophages (TAMs) in breast cancer; however, the detailed…”
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IL-32 production from lung adenocarcinoma cells is potentially involved in immunosuppressive microenvironment by Zhao, Shukang, Li, Lianbo, Komohara, Yoshihiro, Matsubara, Eri, Shinchi, Yusuke, Adawy, Ahmad, Yano, Hiromu, Pan, Cheng, Fujiwara, Yukio, Ikeda, Koei, Suzu, Shinya, Hibi, Taizo, Suzuki, Makoto

“…Interleukin 32 (IL-32) is a proinflammatory cytokine secreted from several kinds of cancer cells. In the present study, we investigated the significance of…”
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Clinical impact of TROP2 in non‐small lung cancers and its correlation with abnormal p53 nuclear accumulation by Mito, Remi, Matsubara, Eri, Komohara, Yoshihiro, Shinchi, Yusuke, Sato, Kensaku, Yoshii, Daiki, Ohnishi, Koji, Fujiwara, Yukio, Tomita, Yusuke, Ikeda, Koei, Sakagami, Takuro, Suzuki, Makoto

“…Tumor‐associated calcium signal transducer 2 (TROP2) is a cell‐surface glycoprotein involved in the high malignant potential of several cancers. Antibody‐drug…”
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Synchronous Multiple Lung Adenocarcinomas: Estrogen Concentration in Peripheral Lung by Ikeda, Koei, Shiraishi, Kenji, Yoshida, Ayaka, Shinchi, Yusuke, Sanada, Mune, Motooka, Yamato, Fujino, Kosuke, Mori, Takeshi, Suzuki, Makoto

“…The detection rate of synchronous multiple lung adenocarcinomas (SMLA), which display multiple ground glass opacity nodules in the peripheral lung, is…”
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Comparison of survivals between sublobar resection and lobar resection for patients with clinical stage I non‐small cell lung cancer and interstitial lung disease: a propensity score matching analysis by Matsushima, Ryohei, Fujino, Kosuke, Motooka, Yamato, Yamada, Hiroyuki, Shirakami, Chika, Shinchi, Yusuke, Osumi, Hironobu, Yamada, Tatsuya, Yoshimoto, Kentaro, Ikeda, Koei, Kubota, Ichiro, Suzuki, Makoto

“…Background Patients with early‐stage lung cancer and interstitial lung disease have a poorer prognosis than those without interstitial lung disease. This study…”
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NUF2 Expression in Cancer Tissues and Lymph Nodes Suggests Post-Surgery Recurrence of Non-Small Cell Lung Cancer by Shirakami, Chika, Ikeda, Koei, Hinokuma, Hironori, Nishi, Wataru, Shinchi, Yusuke, Matsubara, Eri, Osumi, Hironobu, Fujino, Kosuke, Suzuki, Makoto

“…In non-small cell lung cancer (NSCLC) cases, detecting potential lymph node metastases is essential to determine the indications for sublobar resection or…”
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A Case of Pancreatic Side Effects Resulting from Sorafenib and Axitinib Treatment of Stage IV Renal Cell Carcinoma by Kitamura, Yosuke, Yoshii, Hidehiko, Nishimoto, Koshiro, Shinchi, Yusuke, Tokonabe, Shigeki, Takao, Masaya, Daido, Yuichiro

“…Tyrosine kinase inhibitors such as sorafenib and axitinib were developed to treat malignancies, including stage IV renal cell carcinoma. Recently, we…”
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Metastatic Renal Cell Carcinoma in Paranasal Sinus for which Periodic Drug Withdrawal Schedule of Axitinib was Effective : A Case Report by Arai, Yuichi, Ito, Keiichi, Tachi, Kazuyoshi, Koga, Akio, Shinchi, Yusuke, Masunaga, Ayako, Isono, Makoto, Asano, Tomohiko

“…A 73-year-old male patient underwent a right nephrectomy for renal cell carcinoma in 2008, and interferon-alpha was initiated as adjuvant treatment. Computed…”
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Clinical outcomes of percutaneous radiofrequency ablation for small renal cancer by Ito, Keiichi, Soga, Shigeyoshi, Seguchi, Kenji, Shinchi, Yusuke, Masunaga, Ayako, Tasaki, Shinsuke, Kuroda, Kenji, Sato, Akinori, Asakuma, Junichi, Horiguchi, Akio, Shinmoto, Hiroshi, Kaji, Tatsumi, Asano, Tomohiko

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The Significance of SPP1 in Lung Cancers and Its Impact as a Marker for Protumor Tumor-Associated Macrophages by Matsubara, Eri, Yano, Hiromu, Pan, Cheng, Komohara, Yoshihiro, Fujiwara, Yukio, Zhao, Shukang, Shinchi, Yusuke, Kurotaki, Daisuke, Suzuki, Makoto

“…Macrophages are a representative cell type in the tumor microenvironment. Macrophages that infiltrate the cancer microenvironment are referred to as…”
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SPP1 Derived from Macrophages Is Associated with a Worse Clinical Course and Chemo-Resistance in Lung Adenocarcinoma by Matsubara, Eri, Komohara, Yoshihiro, Esumi, Shigeyuki, Shinchi, Yusuke, Ishizuka, Shiho, Mito, Remi, Pan, Cheng, Yano, Hiromu, Kobayashi, Daiki, Fujiwara, Yukio, Ikeda, Koei, Sakagami, Takuro, Suzuki, Makoto

“…Osteopontin, also called secreted phosphoprotein 1 (SPP1), is a multifunctional secreted phosphorylated glycoprotein. SPP1 is also expressed in tumor cells,…”
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PD21-09 MYOFIBROBLAST-DOMINANT PROLIFERATION BUT NOT FIBROBLAST PROLIFERATION ASSOCIATES WITH MORE SEVERE FIBROSIS IN BULBAR URETHRAL STRICTURE by Hirano, Yusuke, Horiguchi, Akio, Shinchi, Yusuke, Ito, Keiichi, Asano, Tomohiko, Miyai, Kosuke

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Clinical outcomes of percutaneous radiofrequency ablation for small renal cancer by Ito, Keiichi, Soga, Shigeyoshi, Seguchi, Kenji, Shinchi, Yusuke, Masunaga, Ayako, Tasaki, Shinsuke, Kuroda, Kenji, Sato, Akinori, Asakuma, Junichi, Horiguchi, Akio, Shinmoto, Hiroshi, Kaji, Tatsumi, Asano, Tomohiko

“…Partial nephrectomy is the treatment of choice for small renal cell carcinoma (RCC) from the perspective of cancer management and renal function. However, when…”
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