Search Results - "Shinagawa, Morikazu"

Microglial Cell Line Established from Prion Protein-Overexpressing Mice Is Susceptible to Various Murine Prion Strains by IWAMARU, Yoshifumi, TAKENOUCHI, Takato, OKADA, Hiroyuki, SHINAGAWA, Morikazu, KITANI, Hiroshi, YOKOYAMA, Takashi, OGIHARA, Kazumasa, HOSHINO, Megumi, TAKATA, Masuhiro, IMAMURA, Morikazu, TAGAWA, Yuichi, HAYASHI-KATO, Hiroko, USHIKI-KAKU, Yuko, SHIMIZU, Yoshihisa

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Accumulation of Mono-Glycosylated Form-Rich, Plaque-Forming PrPSc in the Second Atypical Bovine Spongiform Encephalopathy Case in Japan by Hagiwara, Ken’ichi, Yamakawa, Yoshio, Sato, Yuko, Nakamura, Yuko, Tobiume, Minoru, Shinagawa, Morikazu, Sata, Tetsutaro

“…The recent identification of several atypical cases of bovine spongiform encephalopathy (BSE) has raised the possibility of the existence of distinct strains…”
Get full text

Antigenic characterization of an abnormal isoform of prion protein using a new diverse panel of monoclonal antibodies by Kim, Chan-Lan, Umetani, Atsushi, Matsui, Toshio, Ishiguro, Naotaka, Shinagawa, Morikazu, Horiuchi, Motohiro

“…We established a panel of monoclonal antibodies (mAbs) against prion protein (PrP) by immunizing PrP gene-ablated mice with the pathogenic isoform of prion…”
Get full text

Cell-surface retention of PrPC by anti-PrP antibody prevents protease-resistant PrP formation by Kim, Chan-Lan, Karino, Ayako, Ishiguro, Naotaka, Shinagawa, Morikazu, Sato, Motoyoshi, Horiuchi, Motohiro

“…1 Laboratory of Veterinary Public Health, Obihiro University of Agriculture and Veterinary Medicine, Inada-cho, Obihiro, Hokkaido 080-8555, Japan 2 Laboratory…”
Get full text

Protein misfolding cyclic amplification as a rapid test for assessment of prion inactivation by Murayama, Yuichi, Yoshioka, Miyako, Horii, Hiroko, Takata, Masuhiro, Yokoyama, Takashi, Sudo, Takashi, Sato, Koichi, Shinagawa, Morikazu, Mohri, Shirou

“…Abnormal isoform of prion proteins (PrP Sc), which are infectious agents associated with prion diseases, retain infectivity after undergoing routine…”
Get full text

Experimental Transmission of Two Young and One Suspended Bovine Spongiform Encephalopathy (BSE) Cases to Bovinized Transgenic Mice by Yokoyama, Takashi, Masujin, Kentaro, Yamakawa, Yoshio, Sata, Tetsutaro, Murayama, Yuichi, Shu, Yujing, Okada, Hiroyuki, Mohri, Shirou, Shinagawa, Morikazu

“…Bovine spongiform encephalopathy (BSE) is caused by a prion that primarily consists of an abnormal isoform of the prion protein (PrPSc). Since PrPSc is…”
Get full text

Bacteriological and Genetic Assessment of Game Meat from Japanese Wild Boars by Naya, Yuka, Horiuchi, Motohiro, Ishiguro, Naotaka, Shinagawa, Morikazu

“…Bacterial tests were used to assess bacterial contamination of game meat from Japanese wild boars. The bacterial contamination of wild boar meat was less than…”
Get full text

Effect of tissue deterioration on postmortem BSE diagnosis by immunobiochemical detection of an Abnormal isoform of prion protein by Hayashi, H. (National Inst. of Animal Health, Tsukuba, Ibaraki (Japan)), Takata, M, Iwamaru, Y, Ushiki, Y, Kimura, K.M, Tagawa, Y, Shinagawa, M, Yokoyama, T

“…Surveillance for bovine spongiform encephalopathy (BSE) in fallen stock in Japan is conducted with a commercial enzyme-linked immunosorbent assay (ELISA) for…”
Get full text

Rapid PrPSc Detection in Lymphoid Tissue and Application to Scrapie Surveillance of Fallen Stock in Japan: Variable PrPSc Accumulation in Palatal Tonsil in Natural Scrapie by Shimada, Kimi, Hayashi, Hiroko K., Ookubo, Yuka, Iwamaru, Yoshifumi, Imamura, Morikazu, Takata, Masuhiro, Schmerr, Mary Jo, Shinagawa, Morikazu, Yokoyama, Takashi

“…Rapid western blot (WB) procedure for an abnormal isoform of prion protein (PrPSc) detection in lymphoid tissues was established and has been applied to the…”
Get full text

Amino acid polymorphisms of PrP gene in Mongolian sheep by Gombojav, A. (Obihiro Univ. of Agriculture and Veterinary Medicine, Hokkaido (Japan)), Ishiguro, N, Horiuchi, M, Serjmyadag, D, Byambaa, B, Shinagawa, M

“…To characterize amino acid polymorphisms in sheep prion protein (PrP), we analyzed the PrP genes from 271 sheep of 4 breeds (Khalkh, Yeroo, Orkhon and Khangai)…”
Get full text

Alymphoplasia mice are resistant to prion infection via oral route by Horiuchi, M.(Hokkaido Univ., Sapporo (Japan)), Furuoka, H, Kitamura, N, Shinagawa, M

“…The major cause of infection in animal prion diseases is thought to be consumption of prion-contaminated stuff. There is evidence that the enteric nerve system…”
Get full text

Polymorphisms of caprine PrP gene detected in Japan by Kurosaki, Y. (Obihiro Univ. of Agriculture and Veterinary Medicine, Hokkaido (Japan)), Ishiguro, N, Horiuchi, M, Shinagawa, M

“…Polymorphism of the PrP gene is a primary factor influencing susceptibility and incubation period in natural and experimental scrapie in sheep and goats…”
Get full text

Biological and Biochemical Characterization of Sheep Scrapie in Japan by HORIUCHI, Motohiro, NEMOTO, Takuya, ISHIGURO, Naotaka, FURUOKA, Hidefumi, MOHRI, Shirou, SHINAGAWA, Morikazu

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Photoinactivation of Virus Infectivity by Hypocrellin A by Hirayama, Junichi, Ikebuchi, Kenji, Abe, Hideki, Kwon, Kil-Won, Ohnishi, Yoshiko, Horiuchi, Motohiro, Shinagawa, Morikazu, Ikuta, Kazuyoshi, Kamo, Naoki, Sekiguchi, Sadayoshi

“…— We investigated the photoinactivation of virus infectivity by hypocrellin A and its mechanism. The titers of vesicular stomatitis virus (VSV) and human…”
Get full text

Unique amino acid polymorphisms of PrP genes in Mongolian sheep breeds by Gombojav, A. (Obihiro Univ. of Agriculture and Veterinary Medicine, Hokkaido (Japan)), Ishiguro, N, Horiuchi, M, Shinagawa, M

“…To characterize amino acid polymorphisms of sheep prion protein (PrP) gene, DNA from 740 sheep of nine breeds raised in Mongolia was isolated and analyzed. A…”
Get full text

A genetic method to distinguish crossbred Inobuta from Japanese wild boars by Ishiguro, Naotaka, Naya, Yuka, Horiuchi, Motohiro, Shinagawa, Morikazu

“…To distinguish pig-wild boar crossbred Inobuta from Japanese wild boar populations, a genetic method by using mitochondrial DNA (mtDNA) haplotypes and the…”
Get more information

Effective antigen-retrieval method for immunohistochemical detection of abnormal isoform of prion proteins in animals by Furuoka, Hidefumi, Yabuzoe, Atushi, Horiuchi, Motohiro, Tagawa, Yuichi, Yokoyama, Takashi, Yamakawa, Yoshio, Shinagawa, Morikazu, Sata, Tetsutaro

Get full text

Characterization of the bovine prion protein gene: The expression requires interaction between the promoter and intron by Inoue, S. (Obihiro Univ. of Agriculture and Veterinary Medicine, Hokkaido (Japan)), Tanaka, M, Horiuchi, M, Ishiguro, N, Shinagawa, M

“…We cloned the part of the bovine PrP gene which contains the 5'-flanking region, exon 1, exon 2 and intron 1 to analyze its promoter region. The 5' non-coding…”
Get full text

Characterization of antibodies raised against bovine-PrP-peptides by Takahashi, H, Takahashi, R H, Hasegawa, H, Horiuchi, M, Shinagawa, M, Yokoyama, T, Kimura, K, Haritani, M, Kurata, T, Nagashima, K

“…To analyze the antigenicity of peptides derived from bovine prion protein (PrP) cDNA, we immunized rabbits with four synthetic peptides and compared the…”
Get more information

Isolation of Scrapie Agent from the Placenta of Sheep with Natural Scrapie in Japan by Onodera, Takashi, Ikeda, Toshio, Muramatsu, Yasukazu, Shinagawa, Morikazu

“…A five-month-pregnant Suffolk sheep histologically diagnosed as spontaneous scrapie was studied. Western blot analysis was performed with rabbit serum against…”
Get full text