Search Results - "Shina, Ahuva"

Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor by Khamaisi, Mogher, Toukan, Hala, Axelrod, Jonathan H, Rosenberger, Christian, Skarzinski, Galia, Shina, Ahuva, Meidan, Rina, Koesters, Robert, Rosen, Seymour, Walkinshaw, Gail, Mimura, Imari, Nangaku, Masaomi, Heyman, Samuel N

“…Renal endothelin-converting enzyme (ECE)-1 is induced in experimental diabetes and following radiocontrast administration, conditions characterized by renal…”
Get more information

Up-regulation of HIF in experimental acute renal failure: Evidence for a protective transcriptional response to hypoxia by Rosenberger, Christian, Heyman, Samuel N., Rosen, Seymour, Shina, Ahuva, Goldfarb, Marina, Griethe, Wanja, Frei, Ulrich, Reinke, Petra, Bachmann, Sebastian, Eckardt, Kai-Uwe

“…Up-regulation of HIF in experimental acute renal failure: Evidence for a protective transcriptional response to hypoxia. Medullary hypoxia is believed to play…”
Get full text

In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli by Nechemia-Arbely, Yael, Khamaisi, Mogher, Rosenberger, Christian, Koesters, Robert, Shina, Ahuva, Geva, Carmit, Shriki, Anat, Klaus, Stephen, Rosen, Seymour, Rose-John, Stefan, Galun, Eithan, Axelrod, Jonathan H, Heyman, Samuel N

“…Summary In vitro studies suggest that combined activation of hypoxia‐inducible factor (HIF) and signal transducer and activator of transcription 3 (STAT3)…”
Get full text

In vitro and in vivo effects of tPA and PAI-1 on blood vessel tone by Nassar, Taher, Akkawi, Sa’ed, Shina, Ahuva, Haj-Yehia, Abdullah, Bdeir, Khalil, Tarshis, Mark, Heyman, Samuel N., Higazi, Abd Al-Roof

“…Tissue type plasminogen activator (tPA) is a key enzyme in the fibrinolytic cascade. In this paper we report that tPA contains 2 independent epitopes that…”
Get full text

Acute-on-chronic renal failure in the rat: functional compensation and hypoxia tolerance by Goldfarb, Marina, Rosenberger, Christian, Abassi, Zaid, Shina, Ahuva, Zilbersat, Fani, Eckardt, Kai U, Rosen, Seymour, Heyman, Samuel N

“…We hypothesized that chronic renal parenchymal disease may predispose to acute renal failure (ARF), facilitating the induction of hypoxic medullary tubular…”
Get more information

Acute kidney injury in the diabetic rat: studies in the isolated perfused and intact kidney by Rosenberger, Christian, Khamaisi, Mogher, Goldfarb, Marina, Shina, Ahuva, Shilo, Vitali, Zilbertrest, Fanni, Rosen, Seymour, Heyman, Samuel N

“…Diabetes leads to chronic renal hypoxia and cellular hypoxia response (mediated by hypoxia-inducible factors) and predisposes to acute kidney injury. We…”
Get more information

A role for erythropoietin in the attenuation of radiocontrast-induced acute renal failure in rats by Goldfarb, Marina, Rosenberger, Christian, Ahuva, Shina, Rosen, Seymour, Heyman, Samuel N

“…Radiocontrast-induced nephropathy (CIN) remains an important iatrogenic cause of acute renal failure in high-risk patients, despite the development of safer…”
Get more information

Compensated heart failure predisposes to outer medullary tubular injury: Studies in rats by Goldfarb, Marina, Abassi, Zaid, Rosen, Seymour, Shina, Ahuva, Brezis, Mayer, Heyman, Samuel N.

“…Compensated heart failure predisposes to outer medullary tubular injury: Studies in rats. Heart failure (HF) is considered a putative factor predisposing to…”
Get full text

Hypoxia-inducible factor-2α-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization by Paliege, Alexander, Rosenberger, Christian, Bondke, Anja, Sciesielski, Lina, Shina, Ahuva, Heyman, Samuel N., Flippin, Lee A., Arend, Michael, Klaus, Stephen J., Bachmann, Sebastian

“…The adaptation of erythropoietin production to oxygen supply is determined by the abundance of hypoxia-inducible factor (HIF), a regulation that is induced by…”
Get full text

Activation of hypoxia-inducible factors ameliorates hypoxic distal tubular injury in the isolated perfused rat kidney by Rosenberger, Christian, Rosen, Seymour, Shina, Ahuva, Frei, Ulrich, Eckardt, Kai-Uwe, Flippin, Lee A., Arend, Michael, Klaus, Stephen J., Heyman, Samuel N.

“…Background. Preconditional activation of HIF with specific prolyl-hydroxylase inhibitors (PHD-I) attenuates proximal tubular injury, induced by warm ischaemia/…”
Get full text

N-acetylcysteine ameliorates renal microcirculation: Studies in rats by Heyman, Samuel N., Goldfarb, Marina, Shina, Ahuva, Karmeli, Fanny, Rosen, Seymor

“…N-acetylcysteine ameliorates renal microcirculation: Studies in rats. N-acetylcysteine (NAC) administration has been shown to ameliorate experimental acute…”
Get full text

ApoSense: a novel technology for functional molecular imaging of cell death in models of acute renal tubular necrosis by Damianovich, Maya, Ziv, Ilan, Heyman, Samuel N, Rosen, Seymour, Shina, Ahuva, Kidron, Dvora, Aloya, Tali, Grimberg, Hagit, Levin, Galit, Reshef, Ayelet, Bentolila, Alfonso, Cohen, Avi, Shirvan, Anat

“…Acute renal tubular necrosis (ATN), a common cause of acute renal failure, is a dynamic, rapidly evolving clinical condition associated with apoptotic and…”
Get full text

Evidence for sustained renal hypoxia and transient hypoxia adaptation in experimental rhabdomyolysis-induced acute kidney injury by Rosenberger, Christian, Goldfarb, Marina, Shina, Ahuva, Bachmann, Sebastian, Frei, Ulrich, Eckardt, Kai-Uwe, Schrader, Thomas, Rosen, Seymour, Heyman, Samuel N.

“…Background. Indirect evidence suggests that hypoxia contributes to the pathophysiology of rhabdomyolysis-induced acute kidney injury (AKI). However, the…”
Get full text

Hypoxia-inducible factor-2[alpha]-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization by Paliege, Alexander, Rosenberger, Christian, Bondke, Anja, Sciesielski, Lina, Shina, Ahuva, Heyman, Samuel N, Flippin, Lee A, Arend, Michael, Klaus, Stephen J, Bachmann, Sebastian

“…The adaptation of erythropoietin production to oxygen supply is determined by the abundance of hypoxia-inducible factor (HIF), a regulation that is induced by…”
Get full text

Erratum to: ApoSense: a novel technology for functional molecular imaging of cell death in models of acute renal tubular necrosis by Damianovich, Maya, Ziv, Ilan, Heyman, Samuel N., Rosen, Seymour, Shina, Ahuva, Kidron, Dvora, Aloya, Tali, Grimberg, Hagit, Levin, Galit, Reshef, Ayelet, Bentolila, Alfonso, Cohen, Avi, Shirvan, Anat

Get full text

Effect of nicotine on the renal microcirculation in anesthetized rats: a potential for medullary hypoxic injury? by Heyman, Samuel N, Goldfarb, Marina, Rosenberger, Christian, Shina, Ahuva, Rosen, Seymour

“…Cigarette smoking has been associated with accelerated renal dysfunction among patients with chronic renal disease. Conceivably, repeated parenchymal hypoxic…”
Get more information

Renal microcirculation and tissue damage during acute ureteral obstruction in the rat: Effect of saline infusion, indomethacin and radiocontrast by Heyman, Samuel N., Fuchs, Shmuel, Jaffe, Ronen, Shina, Ahuva, Ellezian, Lena, Brezis, Mayer, Rosen, Seymour

“…Renal microcirculation and tissue damage during acute ureteral obstruction in the rat: Effect of saline infusion, indomethacin and radiocontrast. Radiocontrast…”
Get full text

The fibrinolytic system attenuates vascular tone: effects of tissue plasminogen activator (tPA) and aminocaproic acid on renal microcirculation by Heyman, Samuel N, Hanna, Zohair, Nassar, Taher, Shina, Ahuva, Akkawi, Sa'ed, Goldfarb, Marina, Rosen, Seymour, Higazi, Abd‐Al Roof

“…The renal medulla is a major source of plasminogen activators (PA), recently shown to induce vasodilation in vitro. Treatment with PA inhibitors has been…”
Get full text

Effect of poly(ADP-ribose) polymerase inhibition on outer medullary hypoxic damage by Darmon, David, Goldfarb, Marina, Shina, Ahuva, Rosen, Seymour, Heyman, Samuel N

“…Poly(ADP-ribose) polymerase (PARP) activation after free-radical-induced DNA damage depletes cellular energy stores and participates in ischemia-reflow injury…”
Get more information

Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization by Paliege, Alexander, Rosenberger, Christian, Bondke, Anja, Sciesielski, Lina, Shina, Ahuva, Heyman, Samuel N, Flippin, Lee A, Arend, Michael, Klaus, Stephen J, Bachmann, Sebastian

“…The adaptation of erythropoietin production to oxygen supply is determined by the abundance of hypoxia-inducible factor (HIF), a regulation that is induced by…”
Get full text