Search Results - "Shin, Yu Mi"
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Antioxidative, anti-inflammatory, and matrix metalloproteinase inhibitory activities of 20(S)-ginsenoside Rg3 in cultured mammalian cell lines
Published in Molecular biology reports (01-01-2013)“…Ginsenoside Rg3 is one of ginsenosides that are the well-known bioactive principles of Panax ginseng . Among the two stereoisomeric forms of Rg3, 20( S…”
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Metabolite Profiling to Evaluate Metabolic Changes in Genetically Modified Protopanaxadiol-Enriched Rice
Published in Plants (Basel) (01-02-2023)“…Event DS rice producing protopanaxadiol (PPD) has been previously developed by inserting dammarenediol-II synthase gene ( ) and PPD synthase gene ( ). We…”
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Facile electrochemical detection of botulinum neurotoxin type E using a two-step proteolytic cleavage
Published in Biosensors & bioelectronics (15-10-2015)“…Facile electrochemical methods for measuring protease concentration or protease activity are essential for point-of-care testing of toxic proteases. However,…”
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Determination of motolimod concentration in rat plasma by liquid chromatography-tandem mass spectrometry and its application in a pharmacokinetic study
Published in Journal of pharmaceutical and biomedical analysis (05-02-2020)“…[Display omitted] •No validated method exists for quantitative analysis of motolimod in plasma.•A reliable LC–MS/MS method was developed for quantifying…”
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AUF1 promotes let-7b loading on Argonaute 2
Published in Genes & development (01-08-2015)“…Eukaryotic gene expression is tightly regulated post-transcriptionally by RNA-binding proteins (RBPs) and microRNAs. The RBP AU-rich-binding factor 1 (AUF1)…”
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Liquid chromatography–tandem mass spectrometry of recombinant human extracellular superoxide dismutase (rhSOD3) in mouse plasma and its application to pharmacokinetic study
Published in Journal of pharmaceutical and biomedical analysis (05-02-2019)“…[Display omitted] •An LC-MS/MS method for recombinant human superoxide dismutase 3 in plasma was developed.•Ni-NTA magnetic beads and tryptic digestion were…”
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Development of a liquid chromatography-tandem mass spectrometry method for assaying cenobamate in rat plasma
Published in Journal of liquid chromatography & related technologies (08-11-2018)“…Cenobamate is a candidate drug that is being evaluated in a phase 3 clinical trial as an epilepsy treatment. In the present study, we developed and validated a…”
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Neonatal outcomes of early preterm births according to the delivery indications
Published in Early human development (01-11-2023)“…OBJECTIVETo compare the neonatal outcomes of early preterm births according to delivery indications and determine the obstetric risk factors associated with…”
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A highly sensitive fluorescent probe that quantifies transthyretin in human plasma as an early diagnostic tool of Alzheimer's disease
Published in Chemical communications (Cambridge, England) (27-08-2019)“…The development of sensitive and reliable fluorescent probes for the early diagnosis of Alzheimer's disease (AD) is highly challenging and plays an important…”
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A highly sensitive and simply operated protease sensor toward point-of-care testing
Published in Analyst (London) (21-04-2016)“…Protease sensors for point-of-care testing (POCT) require simple operation, a detection period of less than 20 minutes, and a detection limit of less than 1 ng…”
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Abstract 265: Epi-magnolin suppresses EGF-induced neoplastic cell transformation by inhibition of Akt/mTOR signaling pathway in JBC Cl41 cells
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract The phosphatidylinositol-3-kinase (PI3K)/Akt/the mammalian target of rapamycin (mTOR) signaling pathway is frequently activated in human cancer and…”
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Label-free electrochemical detection of botulinum neurotoxin type E based on its enzymatic activity using interdigitated electrodes
Published in Applied physics letters (29-02-2016)“…We report a simple label-free electrochemical method of detecting low concentrations of botulinum neurotoxin type E light chain (BoNT/E LC) based on its…”
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A novel bispidinone analog induces S-phase cell cycle arrest and apoptosis in HeLa human cervical carcinoma cells
Published in Oncology reports (01-03-2015)“…2,4,6,8-(3)-Tetranitrophenyl-3,7-diazabicyclo[3.3.1] nonan-9-one (B16), a bispidinone analog, was synthesized to investigate its effects on cell viability, the…”
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