Search Results - "Shin, Soo K"
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Alcohol Induced Brain and Liver Damage: Advantages of a Porcine Alcohol Use Disorder Model
Published in Frontiers in physiology (07-01-2021)“…Alcohol is one of the most commonly abused intoxicants with 1 in 6 adults at risk for alcohol use disorder (AUD) in the United States. As such, animal models…”
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Tanshinone IIA-loaded nanoparticles and neural stem cell combination therapy improves gut homeostasis and recovery in a pig ischemic stroke model
Published in Scientific reports (13-02-2023)“…Impaired gut homeostasis is associated with stroke often presenting with leaky gut syndrome and increased gut, brain, and systemic inflammation that further…”
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Intracisternal administration of tanshinone IIA-loaded nanoparticles leads to reduced tissue injury and functional deficits in a porcine model of ischemic stroke
Published in IBRO neuroscience reports (01-06-2021)“…The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments…”
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Characterization of tissue and functional deficits in a clinically translational pig model of acute ischemic stroke
Published in Brain research (01-06-2020)“…•Acute ischemic stroke impaired the white matter integrity of pig internal capsules.•Increased hemispheric swelling and hemorrhage resulted in notable midline…”
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Tanshinone IIA-Loaded Nanoparticle and Neural Stem Cell Therapy Enhances Recovery in a Pig Ischemic Stroke Model
Published in Stem cells translational medicine (21-10-2022)“…Induced pluripotent stem cell-derived neural stem cells (iNSCs) are a multimodal stroke therapeutic that possess neuroprotective, regenerative, and cell…”
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An Adolescent Porcine Model of Voluntary Alcohol Consumption Exhibits Binge Drinking and Motor Deficits in a Two Bottle Choice Test
Published in Alcohol and alcoholism (Oxford) (29-04-2021)“…Abstract Aims Alcohol is the most commonly abused substance leading to significant economic and medical burdens. Pigs are an attractive model for studying…”
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Abstract WMP119: Tanshinone IIa-loaded Nanoparticles And Induced Pluripotent Stem Cell-derived Neural Stem Cell Therapies Enhance Recovery In A Translational Pig Ischemic Stroke Model
Published in Stroke (1970) (01-02-2022)“…Induced pluripotent stem cell-derived neural stem cells (iNSCs) have led to cellular and functional recovery in ischemic stroke models. However, the…”
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