Search Results - "Shin, Saeam"

Cytogenetic testing by fluorescence in situ hybridization is improved by plasma cell sorting in multiple myeloma by Ha, Jihye, Cho, Hyunsoo, Lee, Taek Gyu, Shin, Saeam, Chung, Haerim, Jang, Ji Eun, Kim, Soo-Jeong, Cheong, June-Won, Lee, Seung-Tae, Kim, Jin Seok, Choi, Jong Rak

“…Accurate detection of cytogenetic abnormalities has become more important for improving risk-adapted treatment strategies in multiple myeloma (MM). However,…”
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Exosome-based detection of EGFR T790M in plasma and pleural fluid of prospectively enrolled non-small cell lung cancer patients after first-line tyrosine kinase inhibitor therapy by Kim, Yoonjung, Shin, Saeam, Lee, Kyung-A

“…The exosomal nucleic acid (exoNA) from the plasma and pleural fluid can potentially provide means to identify genomic changes in non-small cell lung cancer…”
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A Comparative Study for Detection of EGFR Mutations in Plasma Cell-Free DNA in Korean Clinical Diagnostic Laboratories by Kim, Yoonjung, Lee, Kyung-A, Shin, Saeam

“…Liquid biopsies to genotype the epidermal growth factor receptor (EGFR) for targeted therapy have been implemented in clinical decision-making in the field of…”
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Targeted gene panel sequencing in early infantile onset developmental and epileptic encephalopathy by Na, Ji-Hoon, Shin, Saeam, Yang, Donghwa, Kim, Borahm, Kim, Heung Dong, Kim, Sehee, Lee, Joon-Soo, Choi, Jong-Rak, Lee, Seung-Tae, Kang, Hoon-Chul

“…Early-onset developmental and epileptic encephalopathy (DEE) is characterized by repeated seizures beginning within 3 months of birth and severe interictal…”
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Clonal Spread of Extended-Spectrum Cephalosporin-Resistant Enterobacteriaceae Between Companion Animals and Humans in South Korea by Hong, Jun Sung, Song, Wonkeun, Park, Hee-Myung, Oh, Jae-Young, Chae, Jong-Chan, Shin, Saeam, Jeong, Seok Hoon

“…Extended-spectrum cephalosporin (ESC)-resistant is an increasingly important problem in both human and veterinary medicine. The aims of this study were to…”
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Development and validation of sensitive BCR::ABL1 fusion gene quantitation using next-generation sequencing by Lee, Hyeonah, Seo, Jieun, Shin, Saeam, Lee, Seung-Tae, Choi, Jong Rak

“…BCR::ABL1 fusion has significant prognostic value and is screened for chronic myeloid leukemia (CML) disease monitoring as a part of routine molecular testing…”
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A Case of STIL-TAL1 -positive T-lymphoblastic Leukemia With a Minor Philadelphia-positive Clone by Koo, Yu-Kyung, Kim, Hongkyung, Shin, Saeam

“…KCI Citation Count: 0…”
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Enhancing mutation detection in multiple myeloma with an error-corrected ultra-sensitive NGS assay without plasma cell enrichment by Kim, Jin Ju, Kim, Soo-Jeong, Lim, Seoyoung, Lee, Seung-Tae, Choi, Jong Rak, Shin, Saeam, Hwang, Doh Yu

“…Risk stratification in multiple myeloma (MM) patients is crucial, and molecular genetic studies play a significant role in achieving this objective. Enrichment…”
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Clinical Practice Guidelines for Pre-Analytical Procedures of Plasma Epidermal Growth Factor Receptor Variant Testing by Shin, Saeam, Woo, Hye In, Kim, Jong-Won, M D, Yoonjung Kim, Lee, Kyung-A

“…Standardization of cell-free DNA (cfDNA) testing processes is necessary to obtain clinically reliable results. The pre-analytical phase of cfDNA testing…”
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Selecting short length nucleic acids localized in exosomes improves plasma EGFR mutation detection in NSCLC patients by Kim, Yoonjung, Shin, Saeam, Kim, Boyeon, Lee, Kyung-A

“…Exosomal nucleic acid (exoNA) is a feasible target to improve the sensitivity of mutation testing in non-small cell lung cancer patients with limited cell-free…”
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Genetic diagnosis of inborn errors of immunity using clinical exome sequencing by Kwon, Soon Sung, Cho, Youn Keong, Hahn, Seungmin, Oh, Jiyoung, Won, Dongju, Shin, Saeam, Kang, Ji-Man, Ahn, Jong Gyun, Lee, Seung-Tae, Choi, Jong Rak

“…Inborn errors of immunity (IEI) include a variety of heterogeneous genetic disorders in which defects in the immune system lead to an increased susceptibility…”
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Application of CRISPR/Cas9-based mutant enrichment technique to improve the clinical sensitivity of plasma EGFR testing in patients with non-small cell lung cancer by Kim, Boyeon, Kim, Yoonjung, Shin, Saeam, Lee, Seung-Tae, Cho, Jae Yong, Lee, Kyung-A

“…Approximately 50%-60% of secondary resistance to primary EGFR- tyrosine kinase inhibitors (TKI) therapy is caused by acquired p.Thr790Met (T790M) mutation;…”
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NUP214 Rearrangements in Leukemia Patients: A Case Series From a Single Institution by Choi, Yu Jeong, Min, Young Kyu, Lee, Seung-Tae, Choi, Jong Rak, Shin, Saeam

“…The three best-known rearrangements found in leukemia ( , and ) are associated with treatment resistance and poor prognosis. Mouse experiments have shown that…”
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Emergence of multidrug-resistant Providencia rettgeri isolates co-producing NDM-1 carbapenemase and PER-1 extended-spectrum β-lactamase causing a first outbreak in Korea by Shin, Saeam, Jeong, Seok Hoon, Lee, Hyukmin, Hong, Jun Sung, Park, Min-Jeong, Song, Wonkeun

“…Nosocomial outbreak due to carbapenem-resistant Enterobacteriaceae has become serious challenge to patient treatment and infection control. We describe an…”
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A comparative study of next-generation sequencing and fragment analysis for the detection and allelic ratio determination of FLT3 internal tandem duplication by Kim, Jin Ju, Lee, Kwang Seob, Lee, Taek Gyu, Lee, Seungjae, Shin, Saeam, Lee, Seung-Tae

“…Currently, FLT3 internal tandem duplication (ITD) is tested by fragment analysis. With next-generation sequencing (NGS), however, not only FLT3 ITD but also…”
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Comprehensive insights into AML relapse: genetic mutations, clonal evolution, and clinical outcomes by Kim, Namsoo, Hahn, Seungmin, Choi, Yu Jeong, Cho, Hyunsoo, Chung, Haerim, Jang, Ji Eun, Lyu, Chuhl Joo, Lee, Seung-Tae, Choi, Jong Rak, Cheong, June-Won, Shin, Saeam

“…Acute myeloid leukemia (AML) is a complex hematologic malignancy characterized by uncontrolled proliferation of myeloid precursor cells within bone marrow…”
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The Genotype-Phenotype Correlation in Human 5α-Reductase Type 2 Deficiency: Classified and Analyzed from a SRD5A2 Structural Perspective by Seo, Jieun, Shin, Saeam, Kim, Sang-Woon, Kim, Su Jin, Lee, Myeongseob, Song, Kyungchul, Suh, Junghwan, Lee, Seung-Tae, Lee, Yong Seung, Chae, Hyun Wook, Kim, Ho-Seong, Choi, Jong Rak, Han, Sangwon, Kwon, Ahreum

“…The phenotype of the 5α-reductase type 2 deficiency (5αRD2) by the gene mutation varies, and although there have been many attempts, the genotype-phenotype…”
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Monitoring measurable residual disease in paediatric acute lymphoblastic leukaemia using immunoglobulin gene clonality based on next-generation sequencing by Ahn, Won Kee, Yu, Kyunghee, Kim, Hongkyung, Lee, Seung-Tae, Choi, Jong Rak, Han, Jung Woo, Lyu, Chuhl Joo, Hahn, Seungmin, Shin, Saeam

“…Assessment of measurable residual disease (MRD) is an essential prognostic tool for B-lymphoblastic leukaemia (B-ALL). In this study, we evaluated the utility…”
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Corrigendum: Genetic diagnosis of inborn errors of immunity using clinical exome sequencing by Kwon, Soon Sung, Cho, Youn Keong, Hahn, Seungmin, Oh, Jiyoung, Won, Dongju, Shin, Saeam, Kang, Ji-Man, Ahn, Jong Gyun, Lee, Seung-Tae, Choi, Jong Rak

“…[This corrects the article DOI: 10.3389/fimmu.2023.1178582.]…”
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Unraveling trajectories from aplastic anemia to hematologic malignancies: genetic and molecular insights by Kim, Namsoo, Choi, Yu Jeong, Lee, Seung-Tae, Choi, Jong Rak, Lyu, Chuhl Joo, Shin, Saeam, Cheong, June-Won

“…Aplastic anemia (AA), characterized by hematopoietic stem cell deficiency, can evolve into different hematologic malignancies. Our understanding of the genetic…”
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