Search Results - "Shin, Mariko"

Orthovanadate-Induced Vasoconstriction of Rat Mesenteric Arteries Is Mediated by Rho Kinase-Dependent Inhibition of Myosin Light Chain Phosphatase by Ito, Kazuya, Matsuzaki, Mai, Sasahara, Tomoya, Shin, Mariko, Yayama, Katsutoshi

“…Orthovanadate (OVA), a protein tyrosine phosphatase inhibitor, induces vasoconstriction in a Rho kinase-dependent manner. The aim of this study was to…”
Get full text

Peroxisome-Proliferator Regulates Key Enzymes of the Tryptophan-NAD+ Pathway by Shin, Mariko, Ohnishi, Mikiko, Iguchi, Shin, Sano, Keiji, Umezawa, Chisae

“…Structually diverse peroxisome-proliferators (PPs) were investigated regarding their effects on NAD+ level and two key enzyme activities in the tryptophan…”
Get full text

NAD + biosynthesis and metabolic fluxes of tryptophan in hepatocytes isolated from rats fed a clofibrate-containing diet by Shin, Mariko, Mori, Yoshimi, Kimura, Aki, Fujita, Yukari, Yoshida, Kuniko, Sano, Keiji, Umezawa, Chisae

“…Hepatocytes were isolated from rats fed a diet with or without 0.25% clofibrate, and NAD + synthesis by the hepatocytes was determined using either [ carboxyl-…”
Get full text

Metabolic fates of L-tryptophan in Saccharomyces uvarum (Saccharomyces carlsbergensis) by SHIN, M, SHINGUU, T, SANO, K, UMEZAWA, C

“…The metabolism of L-tryptophan by Saccharomyces uvarum (carlsbergensis) was investigated by simultaneous measuring of fluxes through kynureninase, through…”
Get full text

Effect of feeding clofibrate-containing diet on the hepatic NAD+ level in rats by LOO, Yee, SHIN, Mariko, YAMASHITA, Yuka, ISHIGAMI, Mayumi, SASAKI, Mie, SANO, Keiji, UMEZAWA, Chisae

“…Feeding rats with a diet containing 0.25% clofibrate for 2 weeks elevated the hepatic NAD+ and total nicotinate levels significantly. Other peroxisome…”
Get full text

Metabolism of tryptophan to niacin in Saccharomyces uvarum by Shin, M. (Kobe Gakuin Univ. (Japan). Faculty of Pharmacology), Sano, K, Umezawa, C

“…In Saccharomyces uvarum, the effect of metabolic intermediates of the tryptophan-NAD pathway on the niacin-production was investigated. Exogenously added…”
Get full text

Regulation of mouse hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme in the tryptophan-nicotinamide adenine dinucleotide pathway, by hepatocyte nuclear factor 4alpha and peroxisome proliferator-activated receptor alpha by Shin, Mariko, Kim, Insook, Inoue, Yusuke, Kimura, Shioko, Gonzalez, Frank J

“…Nicotinamide adenine dinucleotide (NAD) plays a critical role in the maintenance of cellular energy homeostasis…”
Get more information

Differential Effects of Pyrazinamide and Clofibrate on Gene Expression of Rat Hepatic a-Amino-b-Carboxymuconate-e-Semialdehyde Decarboxylase, a Key Enzyme of the Tryptophan-NAD Pathway by Egashira, Yukari, Sato, Makiko, Sato, Mayuki, Sugawara, Ryoko, Tanabe, Atsushi, Shin, Mariko, Sanada, Hiroo

“…Hepatic α-amino-β-carboxymuconate-e-semialdehyde decarboxylase (ACMSD) [EC4.1.1.45] plays a key role in regulating NAD biosynthesis from tryptophan. The aim of…”
Get full text

Inhibition of L-kynurenine 3-hydroxylase from Saccharomyces carlsbergensis by alpha-keto acid derivatives of branched chain amino acids by Shin, M, Sano, K, Umezawa, C

“…L-Kynurenine 3-hydroxylase [EC 1.14.1.2] was partially purified from the mitochondrial outer membrane fraction of Saccharo-myces carlsbergensis by Sephadex…”
Get full text

Effect of L-tryptophan and L-leucine on biosynthesis of niacin-related compounds in Saccharomyces carlsbergensis by Shin, M, Sano, K, Umezawa, C

“…As a model system for investigating the mechanism of the hepatic NAD-lowering effect of leucine in rats, aerobically grown Saccharomyces carlsbergensis was…”
Get full text

NAD levels in the rat primary cultured hepatocytes affected by peroxisome-proliferators by Shin, Mariko, Ohnishi, Mikiko, Sano, Keiji, Umezawa, Chisae

“…The effect of peroxisome-proliferators (PPs) on the NAD level in primary cultured rat hepatocytes was investigated and compared with that in the liver of rat…”
Get more information

Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway by Egashira, Y, Sato, M, Sugawara, R, Tanabe, A, Shin, M, Sanada, H

“…Hepatic alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD) [EC4.1.1.45] plays a key role in regulating NAD biosynthesis from…”
Get full text

NAD glycohydrolase activity in the liver of rats fed on excess leucine diet and low or high protein diet by Kubota, H, Nomura, K, Yamada, O, Shin, M, Sano, K, Umezawa, C

“…In rats fed for 2 weeks on a 10% casein diet suaolemented with 5% leucine, the hepatic NAD content was lowered when comparing with the control rats pair-fed on…”
Get full text

Effect of branched chain alpha-keto acids on kynurenine 3-hydroxylase from rat liver by Shin, M, Yamada, O, Sano, K, Umezawa, C

“…In the preceding paper, we found that branched chain α-keto acids, α-ketoglutarate and pyruvate were inhibitory to kynurenine 3-hydroxylase [EC 1.14.1.2] from…”
Get full text

Pyridine Nucleotide Levels in Liver of Rats Fed Clofibrate- or Pyrazinamide-Containing Diets by Shin, Mariko, Iwamoto, Nahoko, Yamashita, Masaki, Sano, Keiji, Umezawa, Chisae

“…Hepatic NAD +, NADH, and NADPH were increased significantly 3 days after feeding rats with a 0.25% clofibrate diet, increased further after 8 days, and stayed…”
Get full text

Effect of Thioridazine or Chlorpromazine on Increased Hepatic NAD+ Level in Rats Fed Clofibrate, a Hypolipidaemic Drug by SHIN, MARIKO, ASADA, SUMIYO, MIZUMORI, NANAE, SANO, KEIJI, UMEZAWA, CHISAE

“…The effect of the phenothiazines, thioridazine and chlorpromazine, on the increased hepatic NAD+ level of rats fed clofibrate, a hypolipidaemic drug, has been…”
Get full text

NAD+ biosynthesis from tryptophan in the presence of nicotinic acid or vice versa by rat hepatocytes--effect of clofibrate-feeding by Shin, M, Nakakita, S, Hashimoto, C, Sano, K, Umezawa, C

“…NAD+ biosynthesis from tryptophan in the presence of nicotinic acid or vice versa by rat hepatocytes was investigated. In the control hepatocytes, NAD+…”
Get more information

Metabolic Fates of L-Tryptophan in Saccharomyces uvarum : Saccharomyces carlsbergensis by SHIN, Mariko, SHINGUU, Tetsuro, SANO, Keiji, UMEZAWA, Chisae

“…The metabolism of L-tryptophan by Saccharomyces uvarum (carlsbergensis) was investigated by simultaneous measuring of fluxes through kynureinase, through…”
Get full text

Effect of leucine on intestinal absorption of tryptophan in rats by Umezawa, Chisae, Maeda, Yuko, Haba, Kanji, Shin, Mariko, Sano, Keiji

“…1. To elucidate the causal relation between leucine and the lowering of hepatic NAD content of rats fed on a leucine-excessive diet (Yamada et al. 1979), the…”
Get full text

Nicotinamide N-oxide formation by rat liver microsomes by Nomura, K, Shin, M, Sano, K, Umezawa, C, Shimada, T

Get more information