Search Results - "Shin, Kyeong Jin"
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Molecular Mechanisms Underlying Psychological Stress and Cancer
Published in Current pharmaceutical design (01-01-2016)“…Psychological stress is an emotion experienced when people are under mental pressure or encounter unexpected problems. Extreme or repetitive stress increases…”
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PLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2 and synapsin III
Published in Experimental & molecular medicine (01-11-2023)“…Dopamine neurons are essential for voluntary movement, reward learning, and motivation, and their dysfunction is closely linked to various psychological and…”
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3
Regulation of cargo selection in exosome biogenesis and its biomedical applications in cancer
Published in Experimental & molecular medicine (01-04-2024)“…Extracellular vesicles (EVs), including exosomes, are increasingly recognized as potent mediators of intercellular communication due to their capacity to…”
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Successful treatment of protein-losing enteropathy due to AA amyloidosis with octreotide in a patient with rheumatoid arthritis
Published in Modern rheumatology (01-03-2013)“…Protein-losing enteropathy (PLE) is a rare syndrome of gastrointestinal protein loss that may complicate a variety of diseases. This excessive protein loss…”
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5
G-protein-coupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion
Published in Oncotarget (25-10-2016)“…G-protein-coupled receptor 81 (GPR81) functions as a receptor for lactate and plays an important role in the regulation of anti-lipolytic effects in…”
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LONP1 and ClpP cooperatively regulate mitochondrial proteostasis for cancer cell survival
Published in Oncogenesis (New York, NY) (26-02-2021)“…Mitochondrial proteases are key components in mitochondrial stress responses that maintain proteostasis and mitochondrial integrity in harsh environmental…”
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Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA
Published in eLife (29-12-2021)“…Non-alcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation and imbalances in lipid metabolism in the liver. Although nuclear…”
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Protocol for evaluation of tumor-derived exosome-induced cancer cell metastasis in a mouse model
Published in STAR protocols (15-09-2023)“…Exosomes mediate intracellular communication between cancer cells and the local/distant microenvironment, which promotes systemic dissemination of cancer…”
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Recurrent Insulin Autoimmune Syndrome Caused by α-Lipoic Acid in Type 2 Diabetes
Published in Endocrinology and metabolism (Seoul) (01-12-2013)“…Insulin autoimmune syndrome (IAS) is characterized by spontaneous hypoglycemia caused by insulin autoantibodies in the absence of exogenous insulin…”
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10
Two Cases of Allergy to Insulin in Gestational Diabetes
Published in Endocrinology and metabolism (Seoul) (01-09-2015)“…Allergic reaction to insulin is uncommon since the introduction of human recombinant insulin preparations and is more rare in pregnant than non-pregnant…”
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11
TRAIL & EGFR affibody dual-display on a protein nanoparticle synergistically suppresses tumor growth
Published in Journal of controlled release (01-09-2022)“…The TNF-related apoptosis-inducing ligand (TRAIL) is a promising anticancer drug candidate because it selectively binds to the proapoptotic death receptors,…”
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12
GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
Published in Developmental cell (27-02-2023)“…Exosomes transport a variety of macromolecules and modulate intercellular communication in physiology and disease. However, the regulation mechanisms that…”
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Proteomic profiling of exosomes leads to the identification of novel biomarkers for prostate cancer progression
Published in The FASEB journal (01-04-2018)“…Exosomes are vesicles which have garnered interest due to their diagnostic and therapeutic potential. Isolation of cancer‐derived exosomes is a prerequisite…”
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Phospholipase Cγ1 represses colorectal cancer growth by inhibiting the Wnt/β-catenin signaling axis
Published in Biochemical and biophysical research communications (05-11-2021)“…As essential phospholipid signaling regulators, phospholipase C (PLC)s are activated by various extracellular ligands and mediate intracellular signal…”
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15
Alteration of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase
Published in Nucleic acids research (25-08-2023)“…Abstract Replication protein A (RPA), a eukaryotic single-stranded DNA (ssDNA) binding protein, dynamically interacts with ssDNA in different binding modes and…”
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Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancer
Published in Cancer letters (28-02-2020)“…Androgen receptor (AR) signaling plays a central role in metabolic reprogramming for prostate cancer (PCa) growth and progression. Mitochondria are metabolic…”
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Phospholipase Signaling in Breast Cancer
Published in Advances in experimental medicine and biology (2021)“…Breast cancer progression results from subversion of multiple intra- or intercellular signaling pathways in normal mammary tissues and their microenvironment,…”
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PLCγ1: Potential arbitrator of cancer progression
Published in Advances in biological regulation (01-01-2018)“…Phospholipase C (PLC) is an essential mediator of cellular signaling. PLC regulates multiple cellular processes by generating bioactive molecules such as…”
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NSMF promotes the replication stress-induced DNA damage response for genome maintenance
Published in Nucleic acids research (04-06-2021)“…Abstract Proper activation of DNA repair pathways in response to DNA replication stress is critical for maintaining genomic integrity. Due to the complex…”
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Glucosylceramide synthase regulates adipo‐osteogenic differentiation through synergistic activation of PPARγ with GlcCer
Published in The FASEB journal (01-01-2020)“…Dysregulation of the adipo‐osteogenic differentiation balance of mesenchymal stem cells (MSCs), which are common progenitor cells of adipocytes and…”
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