Search Results - "Shin, Kum Joo"
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Lactobacillus fermentum attenuates the alveolar bone loss in ligature‐induced periodontitis in mice
Published in Oral diseases (01-07-2024)“…Objective This study investigated the effects of Lactobacillus fermentum BELF11 on periodontitis in mice (LIP). Methods Sixty mice were randomly assigned to a…”
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2
A Single Lentiviral Vector Platform for MicroRNA-Based Conditional RNA Interference and Coordinated Transgene Expression
Published in Proceedings of the National Academy of Sciences - PNAS (12-09-2006)“…RNAi is proving to be a powerful experimental tool for the functional annotation of mammalian genomes. The full potential of this technology will be realized…”
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Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor
Published in Molecular pharmacology (01-06-2006)“…2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a widespread environmental pollutant with many toxic effects, including endocrine disruption, reproductive…”
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4
G2 arrest and apoptosis by 2-amino- N-quinoline-8-yl-benzenesulfonamide (QBS), a novel cytotoxic compound
Published in Biochemical pharmacology (01-05-2005)“…We screened a library of 11,000 small molecular weight chemicals, looking for compounds that affect cell viability. We have identified 2-amino-…”
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5
Actin Directly Interacts with Phospholipase D, Inhibiting Its Activity
Published in The Journal of biological chemistry (27-07-2001)“…Mammalian phospholipase D (PLD) plays a key role in several signal transduction pathways and is involved in many diverse functions. To elucidate the complex…”
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6
Lysophosphatidic acid signaling through LPA receptor subtype 1 induces colony scattering of gastrointestinal cancer cells
Published in Journal of cancer research and clinical oncology (01-01-2009)“…Purpose Lysophosphatidic acid (LPA) is a multifunctional lipid mediator involved in triggering tumor cell invasion and metastasis, as well as malignant cell…”
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The Effect of the Lacticaseibacillus paracasei BEPC22 and Lactiplantibacillus plantarum BELP53 Combination (BN-202M) on Body Fat Percentage Loss in Overweight Individuals: A Randomized, Double-Blind, Placebo-Controlled Study
Published in Nutrients (01-07-2024)“…BN-202M is derived from humans and consists of two strains, BEPC22 and BELP53. Body fat reduction effect and safety of BN-202M were assessed in overweight…”
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8
Gene expression profiling of light-induced retinal degeneration in phototransduction gene knockout mice
Published in Experimental & molecular medicine (31-10-2008)“…Exposure to light can induce photoreceptor cell death and exacerbate retinal degeneration. In this study, mice with genetic knockout of several genes,…”
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9
Porcine aortic endothelial cell genes responsive to selected inflammatory stimulators
Published in Journal of Veterinary Medical Science (01-11-2009)“…Use of porcine tissues has been suggested as a promising solution for severe shortage of transplantable human organs. The immediate hurdle for…”
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10
Thiram and Ziram Stimulate Non-Selective Cation Channel and Induce Apoptosis in PC12 Cells
Published in Neurotoxicology (Park Forest South) (01-06-2003)“…The neurotoxicity of dithiocarbamates has been previously reported, however, the detailed mechanism underlying the neurotoxicity is still not fully understood…”
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11
Humanized anti-hepatocyte growth factor (HGF) antibody suppresses innate irinotecan (CPT-11) resistance induced by fibroblast-derived HGF
Published in Oncotarget (15-09-2015)“…The growth factors derived from the microenvironment create an environment conducive to tumor growth and survival. HGF deprivation using neutralizing antibody…”
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12
Molecular cloning and characterization of a novel phospholipase C, PLC-eta
Published in Biochemical journal (01-07-2005)“…PLC (phospholipase C) plays an important role in intracellular signal transduction by hydrolysing phosphatidylinositol 4,5-bisphosphate, a membrane…”
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13
Splicing variants of the orphan G-protein-coupled receptor GPR56 regulate the activity of transcription factors associated with tumorigenesis
Published in Journal of cancer research and clinical oncology (2010)“…Purpose GPR56 is an orphan G-protein-coupled receptor of the adhesion family involved in brain development. In some cancer cells and tissues, GPR56 is highly…”
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14
A sensitive enzyme immunoassay for amygdalin in food extracts using a recombinant antibody
Published in Journal of food protection (01-10-2008)“…Amygdalin (laterile) is a cyanogenic glycoside commonly found in the pits of many fruits and raw nuts. When amygdalin-containing seeds are crushed and…”
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Regulation of Phospholipase C-β3 Activity by Na+/H+ Exchanger Regulatory Factor 2
Published in The Journal of biological chemistry (02-06-2000)“…Among the phospholipase C that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate, four mammalian phospholipase C-β (PLC-β) isotypes (isotypes…”
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Luteolin inhibits the nuclear factor-κB transcriptional activity in Rat-1 fibroblasts
Published in Biochemical pharmacology (15-09-2003)“…Flavonoids are natural polyphenolic compounds that have anti-inflammatory, cytoprotective and anticarcinogenic effects. In this study, we investigated the…”
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Cancer cell-derived IL-1α induces IL-8 release in endothelial cells
Published in Journal of cancer research and clinical oncology (01-01-2008)“…Purpose Cancer cells release a multitude of cytokines and growth factors that influence neighboring cells and help establish a favorable environment for tumor…”
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2,2′,4,6,6′-Pentachlorobiphenyl-Induced Apoptosis Is Limited by Cyclooxygenase-2 Induction
Published in Toxicological sciences (01-02-2005)“…Polychlorinated biphenyls (PCBs), a group of persistent and widespread environmental pollutants, are considered to be immunotoxic, carcinogenic, and to induce…”
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2,2′,4,6,6′-Pentachlorobiphenyl Induces Mitotic Arrest and p53 Activation
Published in Toxicological sciences (01-04-2004)“…Polychlorinated biphenyls (PCBs), a class of persistent organic pollutants (POPs), have been considered to be involved in cancers, but the underlying…”
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Abstract 836: ISU104, a fully human anti-ErbB3 antibody, overcomes acquired cetuximab resistance
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract ErbB3 is noted as one of major causes of acquired cetuximab resistance in colorectal and head and neck cancers. ErbB3 causes activation of alternative…”
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