Search Results - "Shin, John J"

TBC1D23 is a bridging factor for endosomal vesicle capture by golgins at the trans-Golgi by Shin, John J. H., Gillingham, Alison K., Begum, Farida, Chadwick, Jessica, Munro, Sean

“…Shin et al. identify TBC1D23 as an adaptor that interacts both with golgins and endosomal WASH and is required for the delivery of endosome-derived vesicles to…”
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Associations between cognitive and brain volume changes in cognitively normal older adults by Armstrong, Nicole M., An, Yang, Shin, John J., Williams, Owen A., Doshi, Jimit, Erus, Guray, Davatzikos, Christos, Ferrucci, Luigi, Beason-Held, Lori L., Resnick, Susan M.

“…•Greater annual rates of memory decline were associated with greater volume loss in multiple temporal and occipital regions.•Decline in verbal fluency was…”
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Spatial proteomics defines the content of trafficking vesicles captured by golgin tethers by Shin, John J. H., Crook, Oliver M., Borgeaud, Alicia C., Cattin-Ortolá, Jérôme, Peak-Chew, Sew Y., Breckels, Lisa M., Gillingham, Alison K., Chadwick, Jessica, Lilley, Kathryn S., Munro, Sean

“…Intracellular traffic between compartments of the secretory and endocytic pathways is mediated by vesicle-based carriers. The proteomes of carriers destined…”
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Phosphatidic Acid Is a pH Biosensor That Links Membrane Biogenesis to Metabolism by Young, Barry P, Shin, John J.H, Orij, Rick, Chao, Jesse T, Li, Shu Chen, Guan, Xue Li, Khong, Anthony, Jan, Eric, Wenk, Markus R, Prinz, William A, Smits, Gertien J, Loewen, Christopher J.R

“…Recognition of lipids by proteins is important for their targeting and activation in many signaling pathways, but the mechanisms that regulate such…”
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Putting the pH into phosphatidic acid signaling by Shin, John J H, Loewen, Christopher J R

“…The lipid phosphatidic acid (PA) has important roles in cell signaling and metabolic regulation in all organisms. New evidence indicates that PA also has an…”
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Author Correction: TBC1D23 is a bridging factor for endosomal vesicle capture by golgins at the trans-Golgi by Shin, John J. H., Gillingham, Alison K., Begum, Farida, Chadwick, Jessica, Munro, Sean

“…In the version of Supplementary Table 1 originally published with this Article, in the sheet relating to Fig. 3c, all values in the ‘golgin-97-mito’ column…”
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Determinants of the Cancer Drug Funding Process in Canada by Gotfrit, Joanna, Jackson, Ashley, Shin, John J W, Stewart, David J, Mallick, Ranjeeta, Wheatley-Price, Paul

“…Background: Canada has a publicly funded healthcare system with a complex drug funding process. After Health Canada approval to market a drug, the pan-Canadian…”
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Measurement of carotid plaque burden: A tool for predicting and preventing dementia? by Shin, John J., Hachinski, Vladimir, Azarpazhooh, M. Reza, Shariatzadeh, Aidin, Spence, J. David

“…•Strokes markedly increase the risk of dementia from Alzheimer disease, and preventing strokes reduces the risk of dementia. Delaying dementia by 5 years…”
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Systematic identification of genes involved in metabolic acid stress resistance in yeast and their potential as cancer targets by Shin, John J, Aftab, Qurratulain, Austin, Pamela, McQueen, Jennifer A, Poon, Tak, Li, Shu Chen, Young, Barry P, Roskelley, Calvin D, Loewen, Christopher J R

“…A hallmark of all primary and metastatic tumours is their high rate of glucose uptake and glycolysis. A consequence of the glycolytic phenotype is the…”
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Hypoglycemia Prevention and User Acceptance of an Insulin Pump System with Predictive Low Glucose Management by Choudhary, Pratik, Olsen, Birthe S, Conget, Ignacio, Welsh, John B, Vorrink, Linda, Shin, John J

“…The MiniMed 640G sensor-augmented insulin pump system (Medtronic, Inc., Northridge, CA) can automatically suspend insulin delivery in advance of predicted…”
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Reducing Diabetes Burden in Medtronic's Automated Insulin Delivery Systems by Forlenza, Gregory P, Dai, Zheng, Niu, Fang, Shin, John J

“…The MiniMed™ 780G advanced hybrid closed-loop system (MM780G) builds on the basal automation and low-glucose protection features of the MiniMed™ 670G and 770G…”
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Potential Life‐Years Lost: The Impact of the Cancer Drug Regulatory and Funding Process in Canada by Gotfrit, Joanna, Shin, John J.W., Mallick, Ranjeeta, Stewart, David J., Wheatley‐Price, Paul

“…Background Canada has an established publicly funded health care system with a complex drug approval and funding process. After proof of efficacy (POE; key…”
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pH Biosensing by PI4P Regulates Cargo Sorting at the TGN by Shin, John J.H., Liu, Peter, Chan, Leslie J., Ullah, Azmat, Pan, Jingxi, Borchers, Christoph H., Burke, John E., Stefan, Christopher, Smits, Gertien J., Loewen, Christopher J.R.

“…Phosphoinositides, diacylglycerolpyrophosphate, ceramide-1-phosphate, and phosphatidic acid belong to a unique class of membrane signaling lipids that contain…”
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Arabidopsis ABCG Transporters, Which Are Required for Export of Diverse Cuticular Lipids, Dimerize in Different Combinations by McFarlane, Heather E, Shin, John J.H, Bird, David A, Samuels, A. Lacey

“…ATP binding cassette (ABC) transporters play diverse roles, including lipid transport, in all kingdoms. ABCG subfamily transporters that are encoded as…”
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Association of diabetes and hepatitis C infection: epidemiologic evidence and pathophysiologic insights by Bahtiyar, Gül, Shin, John J, Aytaman, Ayse, Sowers, James R, McFarlane, Samy I

“…Up to one third of patients with chronic hepatitis C virus (HCV) develop type 2 diabetes mellitus (DM). This prevalence is much higher than that observed in…”
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Criteria for enhancing reporting of perioperative transfusions in surgical and anaesthesiological studies by Eppler, Michael B, Ganjavi, Conner, Davis, Ryan, Sayegh, Aref S, Hershenhouse, Jacob S, Mokhtar, Daniel, Knudsen, J Everett, Tran, John, Bhardwaj, Lokesh, Shin, John J S, Hemal, Sij, Goldenberg, Mitchell G, Miranda, Gus, Sotelo, Rene, Desai, Mihir, Gill, Inderbir, Cacciamani, Giovanni E

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Differential effect of obesity on bone mineral density in White, Hispanic and African American women: a cross sectional study by Castro, Jonathan P, Joseph, Linda A, Shin, John J, Arora, Surender K, Nicasio, John, Shatzkes, Joshua, Raklyar, Irina, Erlikh, Irina, Pantone, Vincent, Bahtiyar, Gul, Chandler, Leon, Pabon, Lina, Choudhry, Sara, Ghadiri, Nilofar, Gosukonda, Pramodini, Muniyappa, Rangnath, von-Gicyzki, Hans, McFarlane, Samy I

“…Osteoporosis is a major public health problem with low bone mass affecting nearly half the women aged 50 years or older. Evidence from various studies has…”
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Systematic Review and Meta-Analysis of the Effect of Osteoporosis on Fusion Rates and Complications Following Surgery for Degenerative Cervical Spine Pathology by Lechtholz-Zey, Elizabeth A, Ayad, Mina, Gettleman, Brandon S, Mills, Emily S, Shelby, Hannah, Ton, Andy, Shin, John J S, Wang, Jeffrey C, Hah, Raymond J, Alluri, Ram K

“…As the elderly population grows, the increasing prevalence of osteoporosis presents a unique challenge for surgeons. Decreased bone strength and quality are…”
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Hypoglycemia Reduction and Changes in Hemoglobin A1c in the ASPIRE In-Home Study by Weiss, Ram, Garg, Satish K, Bode, Bruce W, Bailey, Timothy S, Ahmann, Andrew J, Schultz, Kenneth A, Welsh, John B, Shin, John J

“…ASPIRE In-Home randomized 247 subjects with type 1 diabetes to sensor-augmented pump therapy with or without the Threshold Suspend (TS) feature, which…”
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Osteoporosis and cardiovascular disease: brittle bones and boned arteries, is there a link? by McFarlane, Samy I, Muniyappa, Ranganath, Shin, John J, Bahtiyar, Gul, Sowers, James R

“…Both osteoporosis and cardiovascular disease (CVD) are major public health problems leading to increased morbidity and mortality. Although traditionally viewed…”
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