Search Results - "Shin, Jinyeon"

Regulation of Lymphatic Function in Obesity by Kataru, Raghu P., Park, Hyeong Ju, Baik, Jung Eun, Li, Claire, Shin, Jinyeon, Mehrara, Babak J.

“…The lymphatic system has many functions, including macromolecules transport, fat absorption, regulation and modulation of adaptive immune responses, clearance…”
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Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function by Kataru, Raghu P, Baik, Jung Eun, Park, Hyeung Ju, Ly, Catherine L, Shin, Jinyeon, Schwartz, Noa, Lu, Theresa T, Ortega, Sagrario, Mehrara, Babak J

“…Exogenous administration of lymphangiogenic growth factors is widely used to study changes in lymphatic function in pathophysiology. However, this approach can…”
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Skin microbiome alterations in upper extremity secondary lymphedema by Campbell, Adana-Christine, Fei, Teng, Baik, Jung Eun, Park, Hyeung Ju, Shin, Jinyeon, Kuonqui, Kevin, Brown, Stav, Sarker, Ananta, Kataru, Raghu P, Mehrara, Babak J

“…Lymphedema is a chronic condition that commonly occur from lymphatic injury following surgical resection of solid malignancies. While many studies have…”
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Pharmacological Treatment of Secondary Lymphedema by Brown, Stav, Dayan, Joseph H, Coriddi, Michelle, Campbell, Adana, Kuonqui, Kevin, Shin, Jinyeon, Park, Hyeung Ju, Mehrara, Babak J, Kataru, Raghu P

“…Lymphedema is a chronic disease that results in swelling and decreased function due to abnormal lymphatic fluid clearance and chronic inflammation. In Western…”
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Tumor-Associated Lymphatics Upregulate MHC-II to Suppress Tumor-Infiltrating Lymphocytes by Li, Claire Y., Park, Hyeung Ju, Shin, Jinyeon, Baik, Jung Eun, Mehrara, Babak J., Kataru, Raghu P.

“…Steady-state lymphatic endothelial cells (LECs) can induce peripheral tolerance by presenting endogenous antigens on MHC class I (MHC-I) molecules. Recent…”
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Pilot Study of Anti-Th2 Immunotherapy for the Treatment of Breast Cancer-Related Upper Extremity Lymphedema by Mehrara, Babak J, Park, Hyeung Ju, Kataru, Raghu P, Bromberg, Jacqueline, Coriddi, Michelle, Baik, Jung Eun, Shin, Jinyeon, Li, Claire, Cavalli, Michele R, Encarnacion, Elizabeth M, Lee, Meghan, Van Zee, Kimberly J, Riedel, Elyn, Dayan, Joseph H

“…Recent studies suggest that Th2 cells play a key role in the pathology of secondary lymphedema by elaborating cytokines such as IL4 and IL13. The aim of this…”
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20. Identifying Risk Alleles For Secondary Lymphedema: A Genome-wide Study by Campbell, Adana, Kuonqui, Kevin, Park, Hyeungju, Shin, Jinyeon, Kataru, Raghu, Mehrara, Babak

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Dysregulation of Lymphatic Endothelial VEGFR3 Signaling in Disease by Kuonqui, Kevin, Campbell, Adana-Christine, Sarker, Ananta, Roberts, Arielle, Pollack, Bracha L, Park, Hyeung Ju, Shin, Jinyeon, Brown, Stav, Mehrara, Babak J, Kataru, Raghu P

“…Vascular endothelial growth factor (VEGF) receptor 3 (VEGFR3), a receptor tyrosine kinase encoded by the gene, plays a significant role in the morphogenesis…”
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Regulation of lymphatic function and injury by nitrosative stress in obese mice by Rehal, Sonia, Kataru, Raghu P., Hespe, Geoffrey E., Baik, Jung Eun, Park, Hyeung Ju, Ly, Catherine, Shin, JinYeon, Mehrara, Babak J.

“…Obesity results in lymphatic dysfunction, but the cellular mechanisms that mediate this effect remain largely unknown. Previous studies in obese mice have…”
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Investigating the Antigens Driving T-Cell Responses in Lymphedema: An Interrogation of Insulin and Insulin Receptor Signaling by Campbell, Adana-Christine, Pollack, Bracha, Ashokan, Gopika, Shin, Jinyeon, Roberts, Arielle, Rubin, Jonathan, Ju Park, Hyeung, Mehrara, Babak

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Structural and Functional Changes in Aged Skin Lymphatic Vessels by Kataru, Raghu P, Park, Hyeung Ju, Shin, Jinyeon, Baik, Jung Eun, Sarker, Ananta, Brown, Stav, Mehrara, Babak J

“…Lymphatic structure and function play a critical role in fluid transport, antigen delivery, and immune homeostasis. A dysfunctional lymphatic system is…”
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P31. Immune Repertoire in Lymphedema: Characterizing the Dendritic Cell Subsets in a Lymphedema Mouse Model by Campbell, Adana-Christine, Roberts, Arielle, Pollack, Bracha J., Ashokan, Gopika, Park, HyeungJu, Shin, Jinyeon, Parisotto, Yollanda, Kataru, Raghu, Brown, Chrysothemis, Mehrara, Babak J.

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148. Extravasated Lymph from Secondary Lymphedema Patients Increases Cellular Permeability and Decreases Lymphatic Endothelial Cell VEGFR3 Expression by Kuonqui, Kevin, Campbell, Adana, Brown, Stav, Ju Park, Hyeung, Sarker, Ananta, Kataru, Raghu P., Shin, Jinyeon, Mehrara, Babak J.

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145. Prolonged Exposure to VEGF-C Induces Resistance to Subsequent Stimulation of VEGFR3 in Lymphatic Endothelial Cells by Kuonqui, Kevin, Ju Park, Hyeung, Campbell, Adana, Brown, Stav, Sarker, Ananta, Shin, Jinyeon, Kataru, Raghu P., Mehrara, Babak J.

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154. Non-invasive Detection of Subclinical Skin Changes in Lymphedema: A Promising Screening Method for Early Stage Disease by Brown, Stav, Dayan, Joseph, Kuonqui, Kevin, Sarker, Anata, Shin, Jinyeon, Mcgrath, Leslie, Coriddi, Michelle, Kataru, Raghu, Mehrara, Babak

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PC32. Non-invasive Detection of Subclinical Skin Changes in Lymphedema: A Promising Screening Method for Early Stage Disease by Brown, Stav, Dayan, Joseph, Coriddi, Michelle, McGrath, Leslie, Kuonqui, Kevin, Shin, Jinyeon, Sarker, Anata, Kataru, Raghu, Mehrara, Babak

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1204 Improving lymphatic function to reduce B cell responses in lupus by Ambler, William G, Howlader, Mir, Chalasani, Madhavi Latha S, Seltzer, Ethan S, Sim, JiHyun, Shin, Jinyeon, Schwartz, Noa, Dasoveanu, Dragos, Carballo, Camila B, Sevim, Ecem, Siddique, Salma, Rodeo, Scott, Erkan, Doruk, Kataru, Raghu P, Mehrara, Babak, Lu, Theresa T

“…BackgroundIn SLE, that ultraviolet radiation exposure can induce both photosensitive skin responses and increased autoantibody titers suggests a critical and…”
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802 Lymphatic dysfunction in lupus contributes to cutaneous photosensitivity and lymph node B cell responses by Ambler, William G, Howlander, Mir, Chalasani, Madhavi Latha S, Seltzer, Ethan S, Sim, JiHyun, Shin, Jinyeon, Schwartz, Noa, Dasoveanu, Dragos, Carballo, Camila B, Sevim, Ecem, Siddique, Salma, Rodeo, Scott, Erkan, Doruk, Kataru, Raghu P, Mehrara, Babak, Lu, Theresa T

“…Patients with systemic lupus erythematosus (SLE) are photosensitive, developing skin inflammation with even ambient ultraviolet radiation (UVR), and this…”
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TGF‐β1 mediates pathologic changes of secondary lymphedema by promoting fibrosis and inflammation by Baik, Jung Eun, Park, Hyeung Ju, Kataru, Raghu P., Savetsky, Ira L., Ly, Catherine L., Shin, Jinyeon, Encarnacion, Elizabeth M., Cavali, Michele R., Klang, Mark G., Riedel, Elyn, Coriddi, Michelle, Dayan, Joseph H., Mehrara, Babak J.

“…Background Secondary lymphedema is a common complication of cancer treatment, and previous studies have shown that the expression of transforming growth…”
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Epithelial mesenchymal transition of epithelial cells induced by TGF-β signaling in lymphedema by Park, Hyeung Ju, Kataru, Raghu P, Shin, Jinyeon P, Mehrara, Babak J

“…TGF-β driven fibrosis of the skin is a key pathologic feature of secondary lymphedema. However, the cellular mechanisms that regulate this process remain…”
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