Search Results - "Shin, Jennifer H."
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Physicochemically Tuned Myofibroblasts for Wound Healing Strategy
Published in Scientific reports (05-11-2019)“…Normal healing of skin wounds involves a complex interplay between many different cellular constituents, including keratinocytes, immune cells, fibroblasts,…”
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Hypoxic postconditioning modulates neuroprotective glial reactivity in a 3D cortical ischemic-hypoxic injury model
Published in Scientific reports (07-11-2024)“…Stroke remains one of the major health challenges due to its high rates of mortality and long-term disability, necessitating the development of effective…”
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3
Islet-like organoids derived from human pluripotent stem cells efficiently function in the glucose responsiveness in vitro and in vivo
Published in Scientific reports (12-10-2016)“…Insulin secretion is elaborately modulated in pancreatic ß cells within islets of three-dimensional (3D) structures. Using human pluripotent stem cells (hPSCs)…”
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Interleukin-17A inhibits adipocyte differentiation in human mesenchymal stem cells and regulates pro-inflammatory responses in adipocytes
Published in Biochemical pharmacology (15-06-2009)“…IL-17A inhibits adipocyte differentiation in hBM-MSCs. IL-17A also stimulates the secretion of pro-inflammatory PGE2, IL-6, and IL-8 from adipocytes. This…”
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5
Focal Adhesion Assembly Induces Phenotypic Changes and Dedifferentiation in Chondrocytes
Published in Journal of cellular physiology (01-08-2016)“…The expansion of autologous chondrocytes in vitro is used to generate sufficient populations for cell‐based therapies. However, during monolayer culture,…”
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Biophysical perspectives to understanding cancer-associated fibroblasts
Published in APL Bioengineering (01-06-2024)“…The understanding of cancer has evolved significantly, with the tumor microenvironment (TME) now recognized as a critical factor influencing the onset and…”
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Nanowire-integrated microfluidic devices for facile and reagent-free mechanical cell lysis
Published in Lab on a chip (21-08-2012)“…Cell lysis is an essential task for the detection of intracellular components. In this work, we introduce novel microfluidic devices integrated with patterned…”
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A sorting strategy for C. elegans based on size-dependent motility and electrotaxis in a micro-structured channel
Published in Lab on a chip (01-01-2012)“…Caenorhabditis elegans (C. elegans) is a model organism widely utilized in various fundamental studies in developmental, neural and behavioural biology. The…”
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Efficient nematode swimming in a shear thinning colloidal suspension
Published in Soft matter (01-01-2016)“…The swimming behavior of a nematode Caenorhabditis elegans (C. elegans) is investigated in a non-Newtonian shear thinning colloidal suspension. At the onset…”
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Differential responses of human liver cancer and normal cells to atmospheric pressure plasma
Published in Applied physics letters (08-08-2011)“…When treated by atmospheric pressure plasma, human liver cancer cells (SK-HEP-1) and normal cells (THLE-2) exhibited distinctive cellular responses, especially…”
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11
Human endothelial colony forming cells from adult peripheral blood have enhanced sprouting angiogenic potential through up-regulating VEGFR2 signaling
Published in International journal of cardiology (15-10-2015)“…Abstract Background Endothelial colony forming cells (ECFCs), a subtype of endothelial progenitor cells, have been studied as a promising cellular source for…”
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12
Collaborative effects of electric field and fluid shear stress on fibroblast migration
Published in Lab on a chip (01-01-2013)“…Cells are inherently exposed to a number of different biophysical stimuli such as electric fields, shear stress, and tensile or compressive stress from the…”
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13
Homogenizing cellular tension by hepatocyte growth factor in expanding epithelial monolayer
Published in Scientific reports (04-04-2017)“…Hepatocyte growth factor (HGF) induces cell migration and scattering by mechanisms that are thought to tip a local balance of competing physical forces;…”
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14
Non-thermal gas plasma-induced endoplasmic reticulum stress mediates apoptosis in human colon cancer cells
Published in Oncology reports (01-10-2016)“…Colorectal cancer is a common type of tumor among both men and women worldwide. Conventional remedies such as chemotherapies pose the risk of side-effects, and…”
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15
High-resolution assessment of multidimensional cellular mechanics using label-free refractive-index traction force microscopy
Published in Communications biology (20-01-2024)“…A critical requirement for studying cell mechanics is three-dimensional assessment of cellular shapes and forces with high spatiotemporal resolution. Traction…”
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Three-Dimensional Spheroid Culture on Polymer-Coated Surface Potentiate Stem Cell Functions via Enhanced Cell–Extracellular Matrix Interactions
Published in ACS biomaterials science & engineering (13-04-2020)“…The aggregation of mesenchymal stem cells (MSCs) into three-dimensional (3D) spheroids has emerged as a promising therapeutic candidate for the treatment of a…”
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17
Reversible Thermal Gradient Device to Control Biased Thermotactic Response of C. elegans
Published in Analytical Sciences (10-12-2019)“…C. elegans exhibits a directional migration toward a remembered temperature setpoint (Ts) by activating thermo-sensorimotor neurons. While cryophilic…”
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ROCK suppression promotes differentiation and expansion of endothelial cells from embryonic stem cell–derived Flk1+ mesodermal precursor cells
Published in Blood (27-09-2012)“…Successful differentiation and expansion of endothelial cells (ECs) from embryonic stem cell (ESC)–derived Flk1+ mesodermal precursor cells (MPCs) requires…”
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Aging Donor-Derived Human Mesenchymal Stem Cells Exhibit Reduced Reactive Oxygen Species Loads and Increased Differentiation Potential Following Serial Expansion on a PEG-PCL Copolymer Substrate
Published in International journal of molecular sciences (25-01-2018)“…Human mesenchymal stem cells (hMSCs) have been widely studied for therapeutic development in tissue engineering and regenerative medicine. They can be…”
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20
The shallow turn of a worm
Published in Journal of experimental biology (01-05-2011)“…When crawling on a solid surface, the nematode Caenorhabditis elegans (C. elegans) moves forward by propagating sinusoidal dorso-ventral retrograde contraction…”
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