Search Results - "Shin, Hyung Ju"

Detection of Circulating Tumor Cells in Human Peripheral Blood Using Surface-Enhanced Raman Scattering Nanoparticles by XU WANG, XIMEI QIAN, BEITLER, Jonathan J, ZHUO GEORGIA CHEN, KHURI, Fadlo R, LEWIS, Melinda M, SHIN, Hyung Ju C, SHUMING NIE, SHIN, Dong M

“…The detection and characterization of circulating tumor cells (CTC) holds great promise for personalizing medicine and optimizing systemic therapy. However,…”
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Drug-coated microneedles for rapid and painless local anesthesia by Baek, Sung-Hyun, Shin, Ju-Hyung, Kim, Yeu-Chun

“…This study showed that drug-coated PLLA (Poly (L-lactide)) microneedle arrays can induce rapid and painless local anesthesia. Microneedle arrays were…”
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Microneedle Vaccination Elicits Superior Protection and Antibody Response over Intranasal Vaccination against Swine-Origin Influenza A (H1N1) in Mice by Shin, Ju-Hyung, Park, Jae-Keun, Lee, Dong-Hun, Quan, Fu-Shi, Song, Chang-Seon, Kim, Yeu-Chun

“…Influenza is one of the critical infectious diseases globally and vaccination has been considered as the best way to prevent. In this study, immunogenicity and…”
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Honokiol enhances paclitaxel efficacy in multi-drug resistant human cancer model through the induction of apoptosis by Wang, Xu, Beitler, Jonathan J, Wang, Hong, Lee, Michael J, Huang, Wen, Koenig, Lydia, Nannapaneni, Sreenivas, Amin, A R M Ruhul, Bonner, Michael, Shin, Hyung Ju C, Chen, Zhuo Georgia, Arbiser, Jack L, Shin, Dong M

“…Resistance to chemotherapy remains a major obstacle in cancer therapy. This study aimed to evaluate the molecular mechanism and efficacy of honokiol in…”
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Chemoprevention of Head and Neck Cancer by Simultaneous Blocking of Epidermal Growth Factor Receptor and Cyclooxygenase-2 Signaling Pathways: Preclinical and Clinical Studies by SHIN, Dong M, HONGZHENG ZHANG, BRANDES, Johann C, GRIST, William J, MORENO-WILLIAMS, Rachel, BEITLER, Jonathan J, THOMAS, Sufi M, ZHENGJIA CHEN, SHIN, Hyung Ju C, GRANDIS, Jennifer R, KHURI, Fadlo R, ZHUO GEORGIA CHEN, SABA, Nabil F, CHEN, Amy Y, NANNAPANENI, Sreenivas, AMIN, A. R. M. Ruhul, MÜLLER, Susan, LEWIS, Melinda, SICA, Gabriel, KONO, Scott

“…We investigated the efficacy and underlying molecular mechanism of a novel chemopreventive strategy combining EGF receptor (EGFR) tyrosine kinase inhibitor…”
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Tumor Growth Inhibition by Simultaneously Blocking Epidermal Growth Factor Receptor and Cyclooxygenase-2 in a Xenograft Model by XIN ZHANG, ZHUO CHEN, MI SUN CHOE, YAN LIN, SUN, Shi-Yong, WIEAND, H. Samuel, SHIN, Hyung Ju C, CHEN, Amy, KHJURI, Fadlo R, SHIN, Dong M

“…Purpose: Our previous study revealed that simultaneously targeting epidermal growth factor receptor (EGFR) tyrosine kinase and cyclooxygenase-2 (COX-2)…”
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Epidermal Growth Factor Receptor-targeted Therapy with C225 and Cisplatin in Patients with Head and Neck Cancer by SHIN, Dong M, DONATO, Nicholas J, CLAYMAN, Gary, PFISTER, David, FALCEY, John, WAKSAL, Harlan, MENDELSOHN, John, WAUN KI HONG, PEREZ-SOLER, Roman, SHIN, Hyung Ju C, WU, Ji Y, ZHANG, Peter, LAWHORN, Kristie, KHURI, Fadlo R, GLISSON, Bonnie S, MYERS, Jeffrey

“…C225, a human-mouse chimerized monoclonal antibody directed against the epidermal growth factor receptor (EGFr), has a synergistic effect with cisplatin in…”
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Interaction between epidermal growth factor receptor– and cyclooxygenase 2–mediated pathways and its implications for the chemoprevention of head and neck cancer by Choe, Mi Sun, Zhang, Xin, Shin, Hyung Ju C, Shin, Dong M, Chen, Zhuo Georgia

“…Head and neck squamous cell carcinoma is a well-known model for chemoprevention studies because of its field cancerization effect, its multistep carcinogenesis…”
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Pharmacodynamics of DT-IgG, a dual-targeting antibody against VEGF-EGFR, in tumor xenografted mice by Hurwitz, Selwyn J., Zhang, Hongzheng, Yun, Sujin, Batuwangala, Thil D., Steward, Michael, Holmes, Steve D., Rycroft, Daniel, Pan, Lin, Tighiouart, Mourad, Shin, Hyung Ju C., Koenig, Lydia, Wang, Yuxiang, Chen, Zhuo (Georgia), Shin, Dong M.

“…Purpose DT-IgG is a fully humanized dual-target therapeutic antibody being developed to simultaneously target epidermal growth factor receptor (EGFR) and…”
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HFT-T, a Targeting Nanoparticle, Enhances Specific Delivery of Paclitaxel to Folate Receptor-Positive Tumors by Wang, Xu, Li, Jun, Wang, Yiqing, Cho, Kwang Jae, Kim, Gloria, Gjyrezi, Ada, Koenig, Lydia, Giannakakou, Paraskevi, Shin, Hyung Ju C, Tighiouart, Mourad, Nie, Shuming, Chen, Zhuo (Georgia), Shin, Dong M

“…Nonspecific distribution of chemotherapeutic drugs (such as paclitaxel) is a major factor contributing to side effects and poor clinical outcomes in the…”
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Biomedical applications of microneedles in therapeutics: recent advancements and implications in drug delivery by Rejinold, N Sanoj, Shin, Ju-Hyung, Seok, Hae Yong, Kim, Yeu-Chun

“…The skin, as the largest organ, is a better option for drug delivery in many diseases. However, most transdermal delivery is difficult due to the low…”
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Phase I Clinical and Pharmacodynamic Evaluation of Oral CI-1033 in Patients with Refractory Cancer by ZINNER, Ralph G, NEMUNAITIS, John, EISEMAN, Irene, SHIN, Hyung Ju C, OLSON, Stephen C, CHRISTENSEN, James, XIN HUANG, LENEHAN, Peter F, DONATO, Nicholas J, SHIN, Dong M

“…Purpose: To determine the tolerability and pharmacokinetics of CI-1033 given daily for 7 days of a 21-day cycle. Tumor response and changes in erbB receptor…”
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Enhanced anti-tumor activity by the combination of the natural compounds (-)-epigallocatechin-3-gallate and luteolin: potential role of p53 by Amin, A R M Ruhul, Wang, Dongsheng, Zhang, Hongzheng, Peng, Shifang, Shin, Hyung Ju C, Brandes, Johann C, Tighiouart, Mourad, Khuri, Fadlo R, Chen, Zhuo Georgia, Shin, Dong M

“…Natural dietary agents have drawn a great deal of attention toward cancer prevention because of their wide safety margin. However, single agent intervention…”
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Effect of zymosan and poly (I:C) adjuvants on responses to microneedle immunization coated with whole inactivated influenza vaccine by Shin, Ju-Hyung, Noh, Jin-Yong, Kim, Kwon-Ho, Park, Jae-Keun, Lee, Ji-Ho, Jeong, Seong Dong, Jung, Dae-Yoon, Song, Chang-Seon, Kim, Yeu-Chun

“…Microneedles are the micrometer size devices used for the delivery of vaccines and biotherapeutics. In order to increase the vaccine efficacy and reduce the…”
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Combination of anti-HER3 antibody MM-121/SAR256212 and cetuximab inhibits tumor growth in preclinical models of head and neck squamous cell carcinoma by Jiang, Ning, Wang, Dongsheng, Hu, Zhongliang, Shin, Hyung Ju C, Qian, Guoqing, Rahman, Mohammad Aminur, Zhang, Hongzheng, Amin, A R M Ruhul, Nannapaneni, Sreenivas, Wang, Xiaojing, Chen, Zhengjia, Garcia, Gabriela, MacBeath, Gavin, Shin, Dong M, Khuri, Fadlo R, Ma, Jun, Chen, Zhuo G, Saba, Nabil F

“…The EGFR monoclonal antibody cetuximab is the only approved targeted agent for treating head and neck squamous cell carcinoma (HNSCC). Yet resistance to…”
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C-di-GMP with influenza vaccine showed enhanced and shifted immune responses in microneedle vaccination in the skin by Shin, Ju-Hyung, Lee, Ji-Ho, Jeong, Seong Dong, Noh, Jin-Yong, Lee, Hyo Won, Song, Chang-Seon, Kim, Yeu-Chun

“…A microneedle is a biomedical device which consists of multiple micron scale needles. It is widely used in various fields to deliver drugs and vaccines to the…”
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Detection of numerical aberrations of chromosomes 7 and 9 in cytologic specimens of pleural malignant mesothelioma by Shin, Hyung Ju C., Shin, Dong M., Tarco, Emily, Sneige, Nour

“…BACKGROUND Accurate diagnosis of malignant mesothelioma (MM) in effusion fluid specimens can be challenging. Previous cytogenetic studies demonstrated that…”
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Chemoprevention of Head and Neck Cancer with Celecoxib and Erlotinib: Results of a Phase Ib and Pharmacokinetic Study by SABA, Nabil F, HURWITZ, Selwyn J, GRIST, William, CHEN, Amy Y, MOORE, Charles E, OWONIKOKO, Taofeek K, RAMALINGAM, Suresh, BEITLER, Jonathan J, NANNAPANENI, Sreenivas, SHIN, Hyung Ju C, GRANDIS, Jennifer R, KHURI, Fadlo R, KONO, Scott A, ZHUO GEORGIA CHEN, SHIN, Dong M, YANG, Chung S, YANG ZHAO, ZHENGJIA CHEN, SICA, Gabe, MÜLLER, Susan, MORENO-WILLIAMS, Rachel, LEWIS, Melinda

“…Epidermal growth factor receptor (EGFR) and COX-2 inhibitors synergistically inhibit head and neck squamous cell carcinoma tumorigenesis in preclinical…”
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Endoscopic ultrasound-guided fine-needle aspiration in 179 cases: the M. D. Anderson Cancer Center experience by Shin, Hyung Ju C, Lahoti, Sandeep, Sneige, Nour

“…Recently, endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has emerged as a diagnostic adjunct for small pancreatic lesions and abdominal and…”
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A dual-targeting antibody against EGFR-VEGF for lung and head and neck cancer treatment by Zhang, Hongzheng, Yun, Sujin, Batuwangala, Thil D., Steward, Michael, Holmes, Steve D., Pan, Lin, Tighiouart, Mourad, Shin, Hyung Ju C., Koenig, Lydia, Park, Wungki, Rycroft, Daniel, Nannapaneni, Sreenivas, Wang, Yuxiang, Chen, Zhuo (Georgia), Shin, Dong M.

“…An antibody simultaneously targeting epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF), two major tumor growth‐driving…”
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