Search Results - "Shin, Hyeon Jun"

4670‐PPI OLEDoS pixel circuit design for wide data voltage range in a 5 V 0.13 μm CMOS process by Shin, Hyeon‐Jun, Kim, Yong‐Duck, Choi, Byong‐Deok

“…OLEDoS displays hold great promise for AR/VR applications, but the ultra‐high pixel density required for microdisplays, exceeding several thousand PPI,…”
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Etoposide induced cytotoxicity mediated by ROS and ERK in human kidney proximal tubule cells by Shin, Hyeon-Jun, Kwon, Hyuk-Kwon, Lee, Jae-Hyeok, Anwar, Muhammad Ayaz, Choi, Sangdun

“…Etoposide (ETO) is a commonly used chemotherapeutic drug that inhibits topoisomerase II activity, thereby leading to genotoxicity and cytotoxicity. However,…”
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Doxorubicin induces cytotoxicity through upregulation of pERK-dependent ATF3 by Park, Eun-Jung, Kwon, Hyuk-Kwon, Choi, Yong-Min, Shin, Hyeon-Jun, Choi, Sangdun

“…Although doxorubicin is commonly used in the treatment of many cancer types, its use in chemotherapy has been limited, largely because of its severe side…”
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Toll‐like receptor 2 antagonists identified through virtual screening and experimental validation by Durai, Prasannavenkatesh, Shin, Hyeon‐Jun, Achek, Asma, Kwon, Hyuk‐Kwon, Govindaraj, Rajiv Gandhi, Panneerselvam, Suresh, Yesudhas, Dhanusha, Choi, Jiwon, No, Kyoung Tai, Choi, Sangdun

“…Toll‐like receptor 2 (TLR2) antagonists are key therapeutic targets because they inhibit several inflammatory diseases caused by surplus TLR2 activation. In…”
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A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice by Kwon, Hyuk-Kwon, Patra, Mahesh Chandra, Shin, Hyeon-Jun, Gui, Xiangai, Achek, Asma, Panneerselvam, Suresh, Kim, Dong-Jin, Song, Suk-Jong, Hong, Riwon, Kim, Kyoung Soo, Kim, Yang Gyun, Lee, Francis Y., Hahm, Dae-Hyun, Lee, Sang Ho, Choi, Sangdun

“…Toll-like receptors (TLRs) recognize pathogen/damage-associated molecular patterns and initiate inflammatory signaling cascades. Occasionally, overexpression…”
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Structural and functional analysis of cell adhesion and nuclear envelope nano-topography in cell death by Kwon, Hyuk-Kwon, Lee, Jae-Hyeok, Shin, Hyeon-Jun, Kim, Jae-Ho, Choi, Sangdun

“…The cell death mechanisms of necrosis and apoptosis generate biochemical and morphological changes in different manners. However, the changes that occur in…”
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A Novel Small-Molecule Inhibitor of Endosomal TLRs Reduces Inflammation and Alleviates Autoimmune Disease Symptoms in Murine Models by Patra, Mahesh Chandra, Achek, Asma, Kim, Gi-Young, Panneerselvam, Suresh, Shin, Hyeon-Jun, Baek, Wook-Yong, Lee, Wang Hee, Sung, June, Jeong, Uisuk, Cho, Eun-Young, Kim, Wook, Kim, Eunha, Suh, Chang-Hee, Choi, Sangdun

“…Toll-like receptors (TLRs) play a fundamental role in the inflammatory response against invading pathogens. However, the dysregulation of TLR-signaling…”
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71‐2: Distinguished Paper: 4,670‐PPI OLEDoS Pixel Circuit Design for Wide Data Voltage Range in a 5V 0.13μm CMOS Process by Shin, Hyeon-Jun, Kim, Yong-Duck, Kim, San, Choi, Byong-Deok

“…OLEDoS displays hold great promise for AR/VR applications, but the ultra‐high pixel density required for microdisplays, exceeding several thousand PPI,…”
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Doxorubicin-induced necrosis is mediated by poly-(ADP-ribose) polymerase 1 (PARP1) but is independent of p53 by Shin, Hyeon-Jun, Kwon, Hyuk-Kwon, Lee, Jae-Hyeok, Gui, Xiangai, Achek, Asma, Kim, Jae-Ho, Choi, Sangdun

“…Necrosis, unregulated cell death, is characterized by plasma membrane rupture as well as nuclear and cellular swelling. However, it has recently been reported…”
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TLR4/MD2 specific peptides stalled in vivo LPS-induced immune exacerbation by Park, Seolhee, Shin, Hyeon-Jun, Shah, Masaud, Cho, Hey-Young, Anwar, Muhammad Ayaz, Achek, Asma, Kwon, Hyuk-Kwon, Lee, Byugsung, Yoo, Tae Hyeon, Choi, Sangdun

“…Abstract Negative regulation of Toll-like receptor-4 (TLR4) is anticipated to control the pathogen-induced exaggerated immune response. However, effective TLR4…”
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Linear and Rationally Designed Stapled Peptides Abrogate TLR4 Pathway and Relieve Inflammatory Symptoms in Rheumatoid Arthritis Rat Model by Achek, Asma, Shah, Masaud, Seo, Ji Young, Kwon, Hyuk-Kwon, Gui, Xiangai, Shin, Hyeon-Jun, Cho, Eun-Young, Lee, Byeong Sung, Kim, Dong-Jin, Lee, Sang Ho, Yoo, Tae Hyeon, Kim, Moon Suk, Choi, Sangdun

“…A mounting evidence exists for the despicable role of the aberrant immune response in the pathogenesis of rheumatoid arthritis (RA), where toll-like receptor 4…”
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Activating transcription factor 3 represses inflammatory responses by binding to the p65 subunit of NF-κB by Kwon, Ji-Woong, Kwon, Hyuk-Kwon, Shin, Hyeon-Jun, Choi, Yong-Min, Anwar, Muhammad Ayaz, Choi, Sangdun

“…Activating transcription factor 3 (ATF3) is induced by inflammatory responses, cell death, cytokines and oxidative stress conditions. ATF3 is a negative…”
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Distinct Roles of Type I and Type III Interferons during a Native Murine β Coronavirus Lung Infection by Sharma, Lokesh, Peng, Xiaohua, Qing, Hua, Hilliard, Brandon K, Kim, Jooyoung, Swaminathan, Anush, Tian, Justin, Israni-Winger, Kavita, Zhang, Cuiling, Habet, Victoria, Wang, Lin, Gupta, Gayatri, Tian, Xuefei, Ma, Yina, Shin, Hyeon-Jun, Kim, Sang-Hun, Kang, Min-Jong, Ishibe, Shuta, Young, Lawrence H, Kotenko, Sergei, Compton, Susan, Wilen, Craig B, Wang, Andrew, Dela Cruz, Charles S

“…Coronaviruses are a major health care threat to humankind. Currently, the host factors that contribute to limit disease severity in healthy young patients are…”
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Mitochondrial antiviral signaling protein is crucial for the development of pulmonary fibrosis by Kim, Sang-Hun, Lee, Jung Yeon, Yoon, Chang Min, Shin, Hyeon Jun, Lee, Sei Won, Rosas, Ivan, Herzog, Erica, Dela Cruz, Charles S, Kaminski, Naftali, Kang, Min-Jong

“…Danger signals, or damage-associated molecular patterns (DAMPs), instigate mitochondrial innate immune responses wherein mitochondrial antiviral signaling…”
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Quasi-Stem Cells Derived from Human Somatic Cells by Chemically Modified Carbon Nanotubes by Lee, Jae-Hyeok, Kwon, Hyuck-Kwon, Shin, Hyeon-Jun, Nam, Gwang-Hyeon, Kim, Jae-Ho, Choi, Sangdun

“…Surface modification of micro- and nanotopography was employed to alter the surface properties of scaffolds for controlling cell attachment, proliferation, and…”
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Transcriptome analysis of Haemaphysalis flava female using Illumina HiSeq 4000 sequencing: de novo assembly, functional annotation and discovery of SSR markers by Sang, Min Kyu, Patnaik, Hongray Howrelia, Park, Jie Eun, Song, Dae Kwon, Jeong, Jun Yang, Hong, Chan Eui, Kim, Yong Tae, Shin, Hyeon Jun, Ziwei, Liu, Hwang, Hee Ju, Park, So Young, Kang, Se Won, Park, Seung-Hwan, Cha, Sung-Jae, Ko, Jung Ho, Shin, E. Hyun, Park, Hong Seog, Jo, Yong Hun, Han, Yeon Soo, Patnaik, Bharat Bhusan, Lee, Yong Seok

“…Abstract Background Ticks are ectoparasites capable of directly damaging their hosts and transmitting vector-borne diseases. The ixodid tick Haemaphysalis…”
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Chitinase 3-like-1 is a therapeutic target that mediates the effects of aging in COVID-19 by Kamle, Suchitra, Ma, Bing, He, Chuan Hua, Akosman, Bedia, Zhou, Yang, Lee, Chang-Min, El-Deiry, Wafik S, Huntington, Kelsey, Liang, Olin, Machan, Jason T, Kang, Min-Jong, Shin, Hyeon Jun, Mizoguchi, Emiko, Lee, Chun Geun, Elias, Jack A

“…COVID-19 is caused by SARS-CoV-2 (SC2) and is more prevalent and severe in elderly and patients with comorbid diseases (CM). Because chitinase 3-like-1…”
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Etoposide Induces Necrosis Through p53-Mediated Antiapoptosis in Human Kidney Proximal Tubule Cells by Kwon, Hyuk-Kwon, Shin, Hyeon-Jun, Lee, Jae-Hyeok, Park, Seol-Hee, Kwon, Min-Cheol, Panneerselvam, Suresh, Lee, Chan Gyu, Kim, Sang Geon, Kim, Jae-Ho, Choi, Sangdun

“…The p53 protein is an important transcription factor that modulates signaling pathways for both cell death and survival. Its antiapoptotic mechanisms that…”
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Transcriptome sequencing of the endangered land snail Karaftohelix adamsi from the Island Ulleung: De novo assembly, annotation, valuation of fitness genes and SSR markers by Park, Jie Eun, Patnaik, Bharat Bhusan, Sang, Min Kyu, Song, Dae Kwon, Jeong, Jun Yang, Hong, Chan Eui, Kim, Yong Tae, Shin, Hyeon Jun, Ziwei, Liu, Patnaik, Hongray Howrelia, Hwang, Hee Ju, Park, So Young, Kang, Se Won, Ko, Jung Ho, Lee, Jun Sang, Park, Hong Seog, Jo, Yong Hun, Han, Yeon Soo, Lee, Yong Seok

“…Background The Bradybaenidae snail Karaftohelix adamsi is endemic to Korea, with the species tracked from Island Ulleung in North Gyeongsang Province of South…”
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A review of the endangered mollusks transcriptome under the threatened species initiative of Korea by Patnaik, Hongray Howrelia, Sang, Min Kyu, Park, Jie Eun, Song, Dae Kwon, Jeong, Jun Yang, Hong, Chan Eui, Kim, Yong Tae, Shin, Hyeon Jun, Ziwei, Liu, Hwang, Hee Ju, Park, So Young, Kang, Se Won, Ko, Jung Ho, Lee, Jun Sang, Park, Hong Seog, Jo, Yong Hun, Han, Yeon Soo, Patnaik, Bharat Bhusan, Lee, Yong Seok

“…Transcriptome studies for conservation of endangered mollusks is a proactive approach towards managing threats and uncertainties facing these species in…”
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