Search Results - "Shimura, Mari"
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Identification of viral protein R of human immunodeficiency virus-1 (HIV) and interleukin-6 as risk factors for malignancies in HIV-infected individuals: A cohort study
Published in PloS one (01-01-2024)“…Despite effective antiretroviral therapy, patients with human immunodeficiency virus type-1 (HIV) suffer from a high frequency of malignancies, but related…”
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Heterochromatin links to centromeric protection by recruiting shugoshin
Published in Nature (11-09-2008)“…The centromere of a chromosome is composed mainly of two domains, a kinetochore assembling core centromere and peri-centromeric heterochromatin regions. The…”
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Chromatin compaction protects genomic DNA from radiation damage
Published in PloS one (09-10-2013)“…Genomic DNA is organized three-dimensionally in the nucleus, and is thought to form compact chromatin domains. Although chromatin compaction is known to be…”
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Cu and Zn isotope ratio variations in plasma for survival prediction in hematological malignancy cases
Published in Scientific reports (02-10-2020)“…We have examined potential changes in the isotopic compositions of Fe, Cu and Zn (using multi-collector inductively coupled plasma-mass spectrometry) and the…”
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5
Soft X-ray ptychography system using a Wolter mirror for achromatic illumination optics
Published in Optics express (18-07-2022)“…A soft X-ray ptychography system using a Wolter mirror for the illumination optics has been developed. By taking advantage of the achromaticity of the optics,…”
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Ultracompact mirror device for forming 20-nm achromatic soft-X-ray focus toward multimodal and multicolor nanoanalyses
Published in Nature communications (07-02-2024)“…Nanoscale soft-X-ray microscopy is a powerful analysis tool in biological, chemical, and physical sciences. To enhance its probe sensitivity and leverage…”
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Publisher Correction: Ultracompact mirror device for forming 20-nm achromatic soft-X-ray focus toward multimodal and multicolor nanoanalyses
Published in Nature communications (14-03-2024)Get full text
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8
Zinc and iron dynamics in human islet amyloid polypeptide-induced diabetes mouse model
Published in Scientific reports (15-03-2023)“…Metal homeostasis is tightly regulated in cells and organisms, and its disturbance is frequently observed in some diseases such as neurodegenerative diseases…”
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Formation Mechanism and Toxicological Significance of Biogenic Mercury Selenide Nanoparticles in Human Hepatoma HepG2 Cells
Published in Chemical research in toxicology (20-12-2021)“…It is widely recognized that the toxicity of mercury (Hg) is attenuated by the simultaneous administration of selenium (Se) compounds in various organisms. In…”
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10
Identification of a cell-penetrating peptide applicable to a protein-based transcription activator-like effector expression system for cell engineering
Published in Biomaterials (01-08-2018)“…Cellular reprogramming is a promising technology in regenerative medicine, but most studies have been performed by using expression vectors. For future…”
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Transforming growth factor-β1 induces cholesterol synthesis by increasing HMG-CoA reductase mRNA expression in keratinocytes
Published in Bioscience, biotechnology, and biochemistry (02-07-2016)“…In this study, we investigated the effect of TGF-β1 on cholesterol synthesis in human keratinocytes. TGF-β1 increased the level of cholesterol and the mRNA…”
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Imaging of intracellular fatty acids by scanning X‐ray fluorescence microscopy
Published in The FASEB journal (01-12-2016)“…ABSTRACT Fatty acids are taken up by cells and incorporated into complex lipids such as neutral lipids and glycerophospholipids. Glycerophospholipids are major…”
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Occupational exposure of platinum-based anti-cancer drugs: five-year monitoring of hair and environmental samples in a single hospital
Published in Journal of occupational medicine and toxicology (London, England) (29-09-2020)“…Occupational exposure to chemotherapeutic agents in hospitals is a critical issue. Here, we focused on occupational exposure to platinum-based anti-cancer…”
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HIV-1 Vpr induces TLR4/MyD88-mediated IL-6 production and reactivates viral production from latency
Published in Journal of leukocyte biology (01-06-2010)“…A TLR4/MyD88 pathway was activated via oxidized phosphatidylcholine caused by Vpr of HIV‐1. Vpr, a HIV‐1 accessory protein, was believed to be present in the…”
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Chromatin folding and DNA replication inhibition mediated by a highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex
Published in Scientific reports (20-04-2016)“…Chromatin DNA must be read out for various cellular functions and copied for the next cell division. These processes are targets of many anticancer agents…”
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Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation
Published in The Journal of cell biology (05-09-2011)“…Although pericentromeric heterochromatin is essential for chromosome segregation, its role in humans remains controversial. Dissecting the function of…”
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Transcription factors interfering with dedifferentiation induce cell type-specific transcriptional profiles
Published in Proceedings of the National Academy of Sciences - PNAS (16-04-2013)“…Transcription factors (TFs) are able to regulate differentiation-related processes, including dedifferentiation and direct conversion, through the regulation…”
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Telomere Visualization in Tissue Sections using Pyrrole–Imidazole Polyamide Probes
Published in Scientific reports (06-07-2016)“…Pyrrole–Imidazole (PI) polyamides bind to specific DNA sequences in the minor groove with high affinity. Specific DNA labeling by PI polyamides does not…”
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Differential Anti-APOBEC3G Activity of HIV-1 Vif Proteins Derived from Different Subtypes
Published in The Journal of biological chemistry (12-11-2010)“…Antiretroviral cytidine deaminase APOBEC3G, which is abundantly expressed in peripheral blood lymphocytes and macrophages, strongly protects these cells…”
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DNA methylation profiling can classify HIV-associated lymphomas
Published in AIDS (London) (20-02-2014)“…BACKGROUND:HIV-positive patients have a 60-fold to 200-fold increased incidence of non-Hodgkin lymphomas, including Burkitt lymphoma, diffuse large B-cell…”
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