Search Results - "Shimoya, Kazuto"

Characterization of immortalized ovarian epithelial cells with BRCA1/2 mutation by Komatsu, Hiroaki, Okawa, Masayo, Kazuki, Yasuhiro, Kazuki, Kanako, Hichiwa, Genki, Shimoya, Kazuto, Sato, Shinya, Taniguchi, Fuminori, Oshimura, Mitsuo, Harada, Tasuku

“…We aimed to elucidate the mechanism underlying carcinogenesis by comparing normal and BRCA1/2- mutated ovarian epithelial cells established via Sendai…”
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Characterization of human anti-EpCAM antibodies for developing an antibody–drug conjugate by Satofuka, Hiroyuki, Wang, Yayan, Yamazaki, Kyotaro, Hamamichi, Shusei, Fukuhara, Takeshi, Rafique, Abdur, Osako, Nana, Kanazawa, Iori, Endo, Takeshi, Miyake, Naomi, Honma, Kazuhisa, Nagashima, Yuichi, Hichiwa, Genki, Shimoya, Kazuto, Abe, Satoshi, Moriwaki, Takashi, Murakami, Yasufumi, Gao, Xu, Kugoh, Hiroyuki, Oshimura, Mitsuo, Ito, Yuji, Kazuki, Yasuhiro

“…We previously generated fully human antibody-producing TC-mAb mice for obtaining potential therapeutic monoclonal antibodies (mAbs). In this study, we…”
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Mice carrying the full-length human immunoglobulin loci produce antigen-specific human antibodies with the lambda light chain by Shimoya, Kazuto, Moriwaki, Takashi, Kazuki, Kanako, Okada, Akane, Baba, Shigenori, Masuda, Yuana, Abe, Satoshi, Kazuki, Yasuhiro

“…The development of antibody drugs through animal immunization typically requires the humanization of host antibodies to address concerns about immunogenicity…”
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