Search Results - "Shimojo, Yosuke"

Probiotic Lactobacillus paracasei A221 improves the functionality and bioavailability of kaempferol-glucoside in kale by its glucosidase activity by Shimojo, Yosuke, Ozawa, Yusuke, Toda, Toshihiko, Igami, Kentaro, Shimizu, Takahiko

“…The interplay between food components and gut microbiota has been considered an important factor affecting the functionality of health-promoting foods. In this…”
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Hepatoprotective effect of fermented ginseng and its major constituent compound K in a rat model of paracetamol (acetaminophen)-induced liver injury by Igami, Kentaro, Shimojo, Yosuke, Ito, Hisatomi, Miyazaki, Toshitsugu, Kashiwada, Yoshiki

“…Objectives This work aimed at evaluating the effect of fermented ginseng (FG) and fermented red ginseng (FRG) against rat liver injury caused by paracetamol…”
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Effect of rosmarinic acid in motor dysfunction and life span in a mouse model of familial amyotrophic lateral sclerosis by Shimojo, Yosuke, Kosaka, Kunio, Noda, Yoshihiro, Shimizu, Takahiko, Shirasawa, Takuji

“…Amyotrophic lateral sclerosis (ALS) is a late‐onset progressive neurodegenerative disease affecting motor neurons. About 2% of patients with the disease are…”
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Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells by Kosaka, Kunio, Mimura, Junsei, Itoh, Ken, Satoh, Takumi, Shimojo, Yosuke, Kitajima, Chieko, Maruyama, Atsushi, Yamamoto, Masayuki, Shirasawa, Takuji

“…Neurotrophins such as NGF promote neuronal survival and differentiation via the cell surface TrkA neurotrophin receptor. Compounds with neurotrophic actions…”
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Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners by Satoh, Takumi, Izumi, Masanori, Inukai, Yuki, Tsutsumi, Yasutaka, Nakayama, Naoto, Kosaka, Kunio, Shimojo, Yosuke, Kitajima, Chieko, Itoh, Ken, Yokoi, Toshio, Shirasawa, Takuji

“…In a previous study, we found that carnosic acid (CA) protected cortical neurons by activating the Keap1/Nrf2 pathway, which activation was initiated by…”
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Fermented Ginseng Contains an Agonist of Peroxisome Proliferator Activated Receptors α and γ by Igami, Kentaro, Shimojo, Yosuke, Ito, Hisatomi, Miyazaki, Toshitsugu, Nakano, Fusako, Kashiwada, Yoshiki

“…Peroxisome proliferator activated receptor (PPAR) is a nuclear receptor that is one of the transcription factors regulating lipid and glucose metabolism…”
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Regulation of caspase-6 and FLIP by the AMPK family member ARK5 by Suzuki, Atsushi, Kusakai, Gen-Ichi, Kishimoto, Atsuhiro, Shimojo, Yosuke, Miyamoto, Sińichi, Ogura, Tsutomu, Ochiai, Atsushi, Esumi, Hiroyasu

“…Colorectal cancer cells are unique in that they escape Fas-mediated cell death in the presence of Fas ligand, and we recently reported that AMP-activated…”
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Involvement of Transforming Growth Factor-β1 Signaling in Hypoxia-induced Tolerance to Glucose Starvation by Suzuki, Atsushi, Kusakai, Gen-ichi, Shimojo, Yosuke, Chen, Jian, Ogura, Tsutomu, Kobayashi, Masanobu, Esumi, Hiroyasu

“…Because survival and growth of human hepatoma cells are maintained by nutrient, especially glucose, glucose starvation induces acute cell death. The cell death…”
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Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1 by Satoh, Takumi, Kosaka, Kunio, Itoh, Ken, Kobayashi, Akira, Yamamoto, Masayuki, Shimojo, Yosuke, Kitajima, Chieko, Cui, Jiankun, Kamins, Joshua, Okamoto, Shu-ichi, Izumi, Masanori, Shirasawa, Takuji, Lipton, Stuart A

“…Electrophilic compounds are a newly recognized class of redox-active neuroprotective compounds with electron deficient, electrophilic carbon centers that react…”
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Effect of Ganoderma lucidum extract on adipocyte differentiation and adiponectin gene expression in the murine pre-adipocyte cell line, 3T3-L1 by Shimojo, Yosuke, Kosaka, Kunio, Shirasawa, Takuji

“…Ganoderma lucidum (G. lucidum), a traditional Chinese medicine, has been used for the treatment of various diseases including cancer and atherosclerosis. In…”
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IGF-1 phosphorylates AMPK-α subunit in ATM-dependent and LKB1-independent manner by Suzuki, Atsushi, Kusakai, Gen-ichi, Kishimoto, Atsuhiro, Shimojo, Yosuke, Ogura, Tsutomu, Lavin, Martin F., Esumi, Hiroyasu

“…Serine/threonine protein kinase AMP-activated protein kinase (AMPK) is a key metabolic stress-responsive factor that promotes the adaptation of cells to their…”
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Involvement of transforming growth factor-beta 1 signaling in hypoxia-induced tolerance to glucose starvation by Suzuki, Atsushi, Kusakai, Gen-ichi, Shimojo, Yosuke, Chen, Jian, Ogura, Tsutomu, Kobayashi, Masanobu, Esumi, Hiroyasu

“…Because survival and growth of human hepatoma cells are maintained by nutrient, especially glucose, glucose starvation induces acute cell death. The cell death…”
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Camosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid-and catechol hydroxyl moieties-dependent manners by SATOH, Takumi, IZUMI, Masanori, SHIRASAWA, Takuji, INUKAI, Yuki, TSUTSUMI, Yasutaka, NAKAYAMA, Naoto, KOSAKA, Kunio, SHIMOJO, Yosuke, KITAJIMA, Chieko, ITOH, Ken, YOKOI, Toshio

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Involvement of Transforming Growth Factor-β1 Signaling in Hypoxia-induced Tolerance to Glucose Starvation by Atsushi Suzuki, Gen-ichi Kusakai, Yosuke Shimojo, Jian Chen, Tsutomu Ogura, Masanobu Kobayashi, Hiroyasu Esumi

“…Because survival and growth of human hepatoma cells are maintained by nutrient, especially glucose, glucose starvation induces acute cell death. The cell death…”
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Regulation of caspase-6 and FLIP by the AMPK family member ARKS by SUZUKI, Atsushi, KUSAKAI, Gen-Ichi, KISHIMOTO, Atsuhiro, SHIMOJO, Yosuke, MIYAMOTO, Sinichi, OGURA, Tsutomu, OCHIAI, Atsushi, ESUMI, Hiroyasu

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