Search Results - "Shimohigashi, Y."

Endocrine Disrupter Bisphenol A Increases In Situ Estrogen Production in the Mouse Urogenital Sinus by ARASE, Shigeki, ISHII, Kenichiro, IGARASHI, Katsuhide, AISAKI, Kenichi, YOSHIO, Yuko, MATSUSHIMA, Ayami, SHIMOHIGASHI, Yasuyuki, ARIMA, Kiminobu, KANNO, Jun, SUGIMURA, Yoshiki

“…The balance between androgens and estrogens is very important in the development of the prostate, and even small changes in estrogen levels, including those of…”
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Plan Quality and Delivery Time Comparisons Between Volumetric Modulated Arc Therapy and Intensity Modulated Radiation Therapy for Scalp Angiosarcoma: A Planning Study Using X-ray Voxel Monte Carlo Algorithm by Toya, R, Kai, Y, Saito, T, Kuraoka, A, Shimohigashi, Y, Nakaguchi, Y, Maruyama, M, Murakami, R, Yamashita, Y, Oya, N

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SU‐E‐T‐129: Angular Dependence and Its Correction of the MatriXXEvolution System for IMRT and VMAT Dose Verification by Shimohigashi, Y, Araki, F, Tominaga, H, Sakata, J

“…Purpose: The purpose of this study was to evaluate the angular dependence of the MatriXX Evolution and establish its correction method to improve the dose…”
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Distinction of the binding modes for human nuclear receptor ERR  between bisphenol A and 4-hydroxytamoxifen by Liu, X., Matsushima, A., Okada, H., Shimohigashi, Y.

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Fine spatial assembly for construction of the phenol-binding pocket to capture bisphenol A in the human nuclear receptor estrogen-related receptor by Liu, X., Matsushima, A., Nakamura, M., Costa, T., Nose, T., Shimohigashi, Y.

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Placenta Expressing the Greatest Quantity of Bisphenol A Receptor ERR  among the Human Reproductive Tissues: Predominant Expression of Type-1 ERR  Isoform by Takeda, Y., Liu, X., Sumiyoshi, M., Matsushima, A., Shimohigashi, M., Shimohigashi, Y.

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Accelerated evolution in the protein-coding regions is universal in crotalinae snake venom gland phospholipase A2 isozyme genes by Nakashima, K, Nobuhisa, I, Deshimaru, M, Nakai, M, Ogawa, T, Shimohigashi, Y, Fukumaki, Y, Hattori, M, Sakaki, Y, Hattori, S

“…The nucleotide sequences of four genes encoding Trimeresurus gramineus (green habu snake, crotalinae) venom gland phospholipase A2 (PLA2; phosphatidylcholine…”
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Hairpin loop and second kringle domain are essential sites for heparin binding and biological activity of hepatocyte growth factor by MIZUMO, K, INOUE, H, HAGIYA, M, SHIMIZU, S, NOSE, T, SHIMOHIGASHI, Y, NAKAMURA, T

“…Hepatocyte growth factor (HGF) has a strong affinity for heparin. About one fourth of HGF secreted from MRC-5 human embryonic lung fibroblast cells was found…”
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Edge-to-face CH/pi interaction between ligand Phe-phenyl and receptor aromatic group in the thrombin receptor activation by Matsushima, A, Fujita, T, Nose, T, Shimohigashi, Y

“…In the ligand/receptor interaction, the side chain phenyl group of phenylalanine (Phe) is involved in a so-called hydrophobic interaction, in which the…”
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Two-step models to predict binding affinity of chemicals to the human estrogen receptor α by three-dimensional quantitative structure-activity relationships (3D-QSARs) using receptor-ligand docking simulation by Akahori, Y., Nakai, M., Yakabe, Y., Takatsuki, M., Mizutani, M., Matsuo, M., Shimohigashi, Y.

“…Binding of chemicals to the estrogen receptor (ER) is known to be a key mode of action of endocrine disruption effects. In this study, combined quantitative…”
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Structural Evidence for Endocrine Disruptor Bisphenol A Binding to Human Nuclear Receptor ERR by Matsushima, A., Kakuta, Y., Teramoto, T., Koshiba, T., Liu, X., Okada, H., Tokunaga, T., Kawabata, S.-i., Kimura, M., Shimohigashi, Y.

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Direct Evidence Revealing Structural Elements Essential for the High Binding Ability of Bisphenol A to Human Estrogen-Related Receptor-γ by Okada, Hiroyuki, Takatoshi Tokunaga, Xiaohui Liu, Sayaka Takayanagi, Ayami Matsushima, Shimohigashi, Yasuyuki

“…BACKGROUND: Various lines of evidence have shown that bisphenol A [BPA;$HO-C_{6}H_{4};-C(CH_{3})_{2}- C_{6}H&_{4}-OH$] acts as an endocrine disruptor when…”
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EP-1956 Image quality of in-treatment 4D-CBCT obtained at various doses in VMAT for SBRT: a phantom study by Shimohigashi, Y., Doi, Y., Maruyama, M., Yotsuji, Y., Kai, Y., Toya, R.

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Applicability of Diagnostic Position PET/CT Images Using a Rigid Image Registration Technique to Delineation of Gross Tumor Volumes for Nasopharyngeal Carcinoma Radiotherapy: An Observer Study by Kai, Y., Arimura, H., Toya, R., Saito, T., Matsuyama, T., Fukugawa, Y., Shimohigashi, Y., Maruyama, M., Oya, N.

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Structural requirements of nociceptin antagonist Ac-RYYRIK-NH2 for receptor binding by Kawano, Michiaki, Okada, Kazushi, Honda, Takeshi, Nose, Takeru, Sakaguchi, Kazuyasu, Costa, Tommaso, Shimohigashi, Yasuyuki

“…Ac‐RYYRIK‐NH2 is a peptide isolated from the peptide library as an antagonist that inhibits the biological activities of nociceptin, a hyperalgesic…”
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SU-F-T-549: Validation of a Method for in Vivo 3D Dose Reconstruction for SBRT Using a New Transmission Detector by Nakaguchi, Y, Shimohigashi, Y, Onizuka, R, Ohno, T

“…Purpose: Recently, there has been increased clinical use of stereotactic body radiation therapy (SBRT). SBRT treatments will strongly benefit from in vivo…”
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SU-F-T-541: Impact of VMAT Dose Calculations with Respiratory Movements in Lung by Komatsu, K, Araki, F, Ohno, T, Shimohigashi, Y, Onizuka, R

“…Purpose: To evaluate dose impact due to respiratory movements for volumetric modulated arc therapy (VMAT) in lung, using deformation technique. Methods: The…”
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Edge-to-Face CH/"" Interaction between Ligand Phe-Phenyl and Receptor Aromatic Group in the Thrombin Receptor Activation by Matsushima, A., Fujita, T., Nose, T., Shimohigashi, Y.

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Interaction Mode of the Phe-Phenyl Group of Thrombin Receptor-Tethered Ligand SFLLRNP in Receptor Activation by Nose, Takeru, Fujita, Tsugumi, Nakajima, Masahide, Inoue, Yoshihisa, Costa, Tommaso, Shimohigashi, Yasuyuki

“…Phenylalanine at position 2 of thrombin receptor-tethered ligand peptide (SFLLRNP) is crucially important for the activation of thrombin receptor. Its…”
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SU‐E‐T‐336: Dosimetric Properties of a New Solid Water High Equivalency Phantom for High‐Energy Photon Beams by Araki, F, Ohno, T, Onitsuka, R, Shimohigashi, Y

“…Purpose: To investigate dosimetric properties in high‐energy photon beams for a Solid Water High Equivalency (SWHE, SW557) phantom (Gammex) which was newly…”
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