Search Results - "Shimizu‐Ibuka, Akiko"
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Regulation of alanine racemase activity by carboxylates and the d‐type substrate d‐alanine
Published in The FEBS journal (01-06-2023)“…Alanine racemases (ALRs) are essential for d‐alanine (d‐Ala) production in bacteria, and many ALRs have a conserved carbamylated lysine residue in the active…”
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Human sweet taste receptor mediates acid-induced sweetness of miraculin
Published in Proceedings of the National Academy of Sciences - PNAS (04-10-2011)“…Miraculin (MCL) is a homodimeric protein isolated from the red berries of Richadella dulcifica. MCL, although flat in taste at neutral pH, has taste-modifying…”
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Effects of Peanut-Skin Procyanidin A1 on Degranulation of RBL-2H3 Cells
Published in Bioscience, biotechnology, and biochemistry (2011)“…Peanut skin contains large amounts of polyphenols having antiallergic effects. We found that a peanut-skin extract (PSE) inhibits the degranulation induced by…”
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Peanut-Skin Polyphenols, Procyanidin A1 and Epicatechin-(4 β→6)-epicatechin-(2 β→O→7, 4 β→8)-catechin, Exert Cholesterol Micelle-Degrading Activity in Vitro
Published in Bioscience, biotechnology, and biochemistry (2013)“…We identified epicatechin-(4 β→6)-epicatechin-(2 β→O→7, 4 β→8)-catechin (EEC) in the skin of the peanut (Arachis hypogaea L.). EEC (a trimer) showed more…”
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Serum Cholesterol Reduction by Feeding a High-Cholesterol Diet Containing a Lower-Molecular-Weight Polyphenol Fraction from Peanut Skin
Published in Bioscience, biotechnology, and biochemistry (2012)“…Feeding a high-cholesterol diet with a water-soluble peanut skin polyphenol fraction to rats reduced their plasma cholesterol level, with an increase in fecal…”
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Hypocholesterolemic effect of peanut skin and its fractions: A case record of rats fed on a high-cholesterol diet
Published in Bioscience, biotechnology, and biochemistry (01-01-2009)“…Peanut skin (PS) is characterized by almost exclusively consisting of polyphenols and fiber. We fractionated PS into a water-soluble fraction (WSF) and…”
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RNA-hydrolyzing activity of metallo-β-lactamase IMP-1
Published in PloS one (30-10-2020)“…Metallo-β-lactamases (MBLs) hydrolyze a wide range of β-lactam antibiotics. While all MBLs share a common αβ/βα-fold, there are many other proteins with the…”
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Polypeptide N-acetylgalactosaminyltransferase-15 regulates adipogenesis in human SGBS cells
Published in Scientific reports (29-08-2024)“…Adipogenesis involves intricate molecular mechanisms regulated by various transcription factors and signaling pathways. In this study, we aimed to identify…”
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Structural and functional analysis of miraculin-like protein from Vitis vinifera
Published in Biochimica et biophysica acta. Proteins and proteomics (01-11-2018)“…The so-called miraculin-like proteins (MLPs) are homologous to miraculin, a homodimeric protein with taste-modifying activity that converts sourness into…”
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Insights Into the Inhibition of MOX-1 β-Lactamase by S02030, a Boronic Acid Transition State Inhibitor
Published in Frontiers in microbiology (14-12-2021)“…The rise of multidrug resistant (MDR) Gram-negative bacteria has accelerated the development of novel inhibitors of class A and C β-lactamases. Presently, the…”
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Long-Chain Fatty Acids Elicit a Bitterness-Masking Effect on Quinine and Other Nitrogenous Bitter Substances by Formation of Insoluble Binary Complexes
Published in Journal of agricultural and food chemistry (30-09-2015)“…We have previously found that fatty acids can mask the bitterness of certain nitrogenous substances through direct molecular interactions. Using isothermal…”
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Identification of key neoculin residues responsible for the binding and activation of the sweet taste receptor
Published in Scientific reports (11-08-2015)“…Neoculin (NCL) is a heterodimeric protein isolated from the edible fruit of Curculigo latifolia . It exerts a taste-modifying activity by converting sourness…”
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Identification and modulation of the key amino acid residue responsible for the pH sensitivity of neoculin, a taste-modifying protein
Published in PloS one (29-04-2011)“…Neoculin occurring in the tropical fruit of Curculigo latifolia is currently the only protein that possesses both a sweet taste and a taste-modifying activity…”
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Roles of Residues Cys69, Asn104, Phe160, Gly232, Ser237, and Asp240 in Extended-Spectrum β-Lactamase Toho-1
Published in Antimicrobial Agents and Chemotherapy (01-01-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Crystal Structure of Pyruvate Kinase from Geobacillus stearothermophilus
Published in Journal of biochemistry (Tokyo) (01-09-2008)“…The pyruvate kinase (PK) from a moderate thermophile, Geobacillus stearothermophilus, is an allosteric enzyme activated by AMP and ribose 5-phosphate but not…”
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Extracellular Production of Neoculin, a Sweet-Tasting Heterodimeric Protein with Taste-Modifying Activity, by Aspergillus oryzae
Published in Applied and Environmental Microbiology (01-05-2006)“…Neoculin (NCL), a protein with sweetness approximately 500-fold that of sugar, can be utilized as a nonglycemic sweetener. It also has taste-modifying activity…”
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Microbial production of sensory-active miraculin
Published in Biochemical and biophysical research communications (24-08-2007)“…Miraculin (MCL), a tropical fruit protein, is unique in that it has taste-modifying activity to convert sourness to sweetness, though flat in taste at neutral…”
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Novel Angiotensin I-Converting Enzyme Inhibitory Peptides Found in a Thermolysin-Treated Elastin with Antihypertensive Activity
Published in Bioscience, biotechnology, and biochemistry (2012)“…Angiotensin I-converting enzyme (ACE) inhibitory activity was generated from elastin and collagen by hydrolyzing with thermolysin. The IC 50 value of 531.6…”
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Bulky high-mannose-type N-glycan blocks the taste-modifying activity of miraculin
Published in Biochimica et biophysica acta (01-09-2010)“…Miraculin (MCL) is a taste-modifying protein that converts sourness into sweetness. The molecular mechanism underlying the taste-modifying action of MCL is…”
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Kinetic Properties of Four Plasmid-Mediated AmpC β-Lactamases
Published in Antimicrobial Agents and Chemotherapy (01-10-2005)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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