Search Results - "Shimizu, Takuto"

Sulfasalazine, an inhibitor of the cystine-glutamate antiporter, reduces DNA damage repair and enhances radiosensitivity in murine B16F10 melanoma by Nagane, Masaki, Kanai, Eiichi, Shibata, Yuki, Shimizu, Takuto, Yoshioka, Chie, Maruo, Takuya, Yamashita, Tadashi

“…The sodium-independent cystine-glutamate antiporter plays an important role in extracellular cystine uptake. It comprises the transmembrane protein, xCT and…”
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Nuclear Envelope and Nuclear Pore Complexes in Neurodegenerative Diseases—New Perspectives for Therapeutic Interventions by Hachiya, Naomi, Sochocka, Marta, Brzecka, Anna, Shimizu, Takuto, Gąsiorowski, Kazimierz, Szczechowiak, Katarzyna, Leszek, Jerzy

“…Transport of proteins, transcription factors, and other signaling molecules between the nucleus and cytoplasm is necessary for signal transduction. The study…”
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Probiotics enhances anti‐tumor immune response induced by gemcitabine plus cisplatin chemotherapy for urothelial cancer by Miyake, Makito, Oda, Yuki, Owari, Takuya, Iida, Kota, Ohnishi, Sayuri, Fujii, Tomomi, Nishimura, Nobutaka, Miyamoto, Tatsuki, Shimizu, Takuto, Ohnishi, Kenta, Hori, Shunta, Morizawa, Yosuke, Gotoh, Daisuke, Nakai, Yasushi, Torimoto, Kazumasa, Tanaka, Nobumichi, Fujimoto, Kiyohide

“…Chemotherapy drugs, such as gemcitabine and cisplatin (GC), are frequently administered to patients with advanced urothelial carcinoma, however the influence…”
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The Japanese health care system-based cost-effectiveness of photodynamic diagnosis-assisted transurethral resection of bladder tumor for non-muscle invasive bladder cancer by Nishimura, Nobutaka, Miyake, Makito, Miyamoto, Tatsuki, Tomizawa, Mitsuru, Shimizu, Takuto, Morizawa, Yosuke, Hori, Shunta, Gotoh, Daisuke, Nakai, Yasushi, Torimoto, Kazumasa, Tanaka, Nobumichi, Fujimoto, Kiyohide

“…Abstract Background Photodynamic diagnosis-assisted transurethral resection of bladder tumor reduces the risk of intravesical recurrence compared with…”
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Volatile Anesthetic Sevoflurane Precursor 1,1,1,3,3,3-Hexafluoro-2-Propanol (HFIP) Exerts an Anti-Prion Activity in Prion-Infected Culture Cells by Shimizu, Takuto, Nogami, Emiko, Ito, Yuka, Morikawa, Kazuo, Nagane, Masaki, Yamashita, Tadashi, Ogawa, Tsuyoshi, Kametani, Fuyuki, Yagi, Hisashi, Hachiya, Naomi

“…Prion disease is a neurodegenerative disorder with progressive neurologic symptoms and accelerated cognitive decline. The causative protein of prion disease is…”
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Supplementary granulocyte macrophage colony‐stimulating factor to chemotherapy and programmed death‐ligand 1 blockade decreases local recurrence after surgery in bladder cancer by Miyake, Makito, Hori, Shunta, Ohnishi, Sayuri, Toritsuka, Michihiro, Fujii, Tomomi, Shimizu, Takuto, Owari, Takuya, Morizawa, Yosuke, Gotoh, Daisuke, Itami, Yoshitaka, Nakai, Yasushi, Anai, Satoshi, Torimoto, Kazumasa, Tanaka, Nobumichi, Fujimoto, Kiyohide

“…Despite advances and refinements in surgery and perioperative chemotherapy, there are still unmet medical needs with respect to radical cystectomy for…”
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Chemotherapy with gemcitabine and cisplatin downregulates tumor expression level of nectin‐4 in a syngeneic model of murine MBT2 urothelial cancer cell line and C3H mice by Miyake, Makito, Oda, Yuki, Nishimura, Nobutaka, Shimizu, Takuto, Fujii, Tomomi, Fujimoto, Kiyohide

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Endothelial ganglioside GM3 regulates angiogenesis in solid tumors by Suzuki, Mira, Nagane, Masaki, Kato, Kazuhiro, Yamauchi, Akinori, Shimizu, Takuto, Yamashita, Hiroko, Aihara, Naoyuki, Kamiie, Junichi, Kawashima, Nagako, Naito, Shokichi, Yamashita, Tadashi

“…Cancer cells require oxygen and nutrients for growth, making angiogenesis one of the essential components of tumor growth. Gangliosides, constituting membrane…”
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Longitudinal assessment of health-related quality of life in Japanese patients with advanced urothelial carcinoma receiving immune check point inhibitors by Miyake, Makito, Nishimura, Nobutaka, Oda, Yuki, Miyamoto, Tatsuki, Iida, Kota, Tomizawa, Mitsuru, Shimizu, Takuto, Owari, Takuya, Ohnishi, Kenta, Hori, Shunta, Morizawa, Yosuke, Gotoh, Daisuke, Nakai, Yasushi, Torimoto, Kazumasa, Fujii, Tomomi, Tanaka, Nobumichi, Fujimoto, Kiyohide

“…Real-world data on health-related quality of life (HRQoL) in advanced urothelial carcinoma (aUC) receiving immune checkpoint inhibitors (ICIs) are limited…”
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Ganglioside GM3 deficiency enhances mast cell sensitivity by Komuro, Mariko, Mizugaki, Hinano, Nagane, Masaki, Morimoto, Misako, Fukuyama, Tomoki, Ogihara, Kikumi, Naya, Yuko, Yokomori, Emi, Kaneshima, Kimika, Kawakami, Yasushi, Kamiie, Junichi, Shibata, Yuki, Suzuki, Mira, Shimizu, Takuto, Kawashima, Nagako, Okamoto, Mariko, Ikeda, Teruo, Yamashita, Tadashi

“…Mast cells are a significant source of cytokines and chemokines that play a role in pathological processes. Gangliosides, which are complex lipids with a sugar…”
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Switch-maintenance avelumab immunotherapy following first-line chemotherapy for patients with advanced, unresectable or metastatic urothelial carcinoma: the first Japanese real-world evidence from a multicenter study by Miyake, Makito, Shimizu, Takuto, Oda, Yuki, Tachibana, Akira, Ohmori, Chihiro, Itami, Yoshitaka, Kiba, Keisuke, Tomioka, Atsushi, Yamamoto, Hiroaki, Ohnishi, Kenta, Nishimura, Nobutaka, Hori, Shunta, Morizawa, Yosuke, Gotoh, Daisuke, Nakai, Yasushi, Torimoto, Kazumasa, Fujii, Tomomi, Tanaka, Nobumichi, Fujimoto, Kiyohide

“…Abstract Objective To develop the first Japanese real-world evidence of switch-maintenance avelumab in advanced, unresectable or metastatic urothelial…”
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Clinical significance of bladder deformity for intravesical recurrence after Bacillus Calmette–Guérin treatment by Shimizu, Takuto, Hori, Shunta, Iemura, Yusuke, Tomioka, Atushi, Miyake, Makito, Fujimoto, Kiyohide

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Clinical practice of UroVysion® urine test in patients with bladder carcinoma in situ treated with intravesical Bacillus Calmette–Guerin by Miyake, Makito, Hori, Shunta, Fujii, Tomomi, Nishimura, Nobutaka, Oda, Yuki, Miyamoto, Tatsuki, Tomizawa, Mitsuru, Shimizu, Takuto, Ohnishi, Kenta, Morizawa, Yosuke, Gotoh, Daisuke, Nakai, Yasushi, Torimoto, Kazumasa, Tanaka, Nobumichi, Fujimoto, Kiyohide

“…Abstract In January 2019, the use of the UroVysion® urine test for surveillance of non-muscle invasive bladder cancer with carcinoma in situ (CIS) was approved…”
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Tumor expression of Nectin-1–4 and its clinical implication in muscle invasive bladder cancer: An intra-patient variability of Nectin-4 expression by Miyake, Makito, Miyamoto, Tatsuki, Shimizu, Takuto, Ohnishi, Sayuri, Fujii, Tomomi, Nishimura, Nobutaka, Oda, Yuki, Morizawa, Yosuke, Hori, Shunta, Gotoh, Daisuke, Nakai, Yasushi, Torimoto, Kazumasa, Tanaka, Nobumichi, Fujimoto, Kiyohide

“…There is limited evidence regarding the tumor expression of nectins and their clinical implications in muscle invasive bladder cancer. Herein, we evaluated…”
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Efficacy of pembrolizumab rechallenge for metastatic urothelial carcinoma by Nishimura, Nobutaka, Miyake, Makito, Shimizu, Takuto, Tachibana, Akira, Tanaka, Nobumichi, Fujimoto, Kiyohide

“…Introduction Before the approval of enfortumab vedotin, no standard treatment was available as the salvage treatment for patients with metastatic urothelial…”
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Clinical significance of limited and extended pelvic lymph node dissection during robot‐assisted radical prostatectomy for patients with localized prostate cancer: A retrospective, propensity score matching analysis by Hori, Shunta, Nakai, Yasushi, Tachibana, Akira, Omori, Chihiro, Nishimura, Nobutaka, Inoue, Kuniaki, Tomizawa, Mitsuru, Shimizu, Takuto, Morizawa, Yosuke, Gotoh, Daisuke, Miyake, Makito, Torimoto, Kazumasa, Yoneda, Tatsuo, Fujimoto, Kiyohide, Tanaka, Nobumichi

“…Objectives We investigated the diagnostic and therapeutic benefits of limited or extended pelvic lymph node dissection during a robot‐assisted radical…”
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Clinical Impact of Sarcopenia and Inflammatory/Nutritional Markers in Patients with Unresectable Metastatic Urothelial Carcinoma Treated with Pembrolizumab by Shimizu, Takuto, Miyake, Makito, Hori, Shunta, Ichikawa, Kazuki, Omori, Chihiro, Iemura, Yusuke, Owari, Takuya, Itami, Yoshitaka, Nakai, Yasushi, Anai, Satoshi, Tomioka, Atsushi, Tanaka, Nobumichi, Fujimoto, Kiyohide

“…Sarcopenia is a muscle loss syndrome known as a risk factor of various carcinomas. The impact of sarcopenia and sarcopenia-related inflammatory/nutritional…”
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Trends in risk classification at diagnosis and choice of primary therapy for prostate cancer: An analysis of 10 839 patients from the Nara Urological Research and Treatment Group registry between 2004 and 2015 by Nakai, Yasushi, Tanaka, Nobumichi, Fujii, Tomomi, Miyake, Makito, Anai, Satoshi, Hori, Shunta, Shimizu, Takuto, Onishi, Mikiko, Ichikawa, Kazuki, Onishi, Kenta, Fujimoto, Kiyohide

“…Objective To evaluate trends in risk classification at diagnosis and choice of primary therapy in patients diagnosed with prostate cancer. Methods This…”
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Photodynamic Therapeutic Effect during 5-Aminolevulinic Acid-Mediated Photodynamic Diagnosis-Assisted Transurethral Resection of Bladder Tumors by Nishimura, Nobutaka, Miyake, Makito, Onishi, Sayuri, Fujii, Tomomi, Miyamoto, Tatsuki, Tomizawa, Mitsuru, Shimizu, Takuto, Morizawa, Yosuke, Hori, Shunta, Gotoh, Daisuke, Nakai, Yasushi, Torimoto, Kazumasa, Tanaka, Nobumichi, Fujimoto, Kiyohide

“…Photodynamic diagnosis-assisted transurethral resection of bladder tumors (PDD-TURBT) enhances detection of elusive lesions compared to standard white…”
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Routine Surveillance of Upper Urinary Tract Imaging for Diagnosing Upper Urinary Tract Urothelial Cancer Recurrence in Patients with Nonmuscle Invasive Bladder Cancer by Nishimura, Nobutaka, Miyake, Makito, Miyamoto, Tatsuki, Shimizu, Takuto, Fujii, Tomomi, Morizawa, Yosuke, Hori, Shunta, Gotoh, Daisuke, Nakai, Yasushi, Torimoto, Kazumasa, Tanaka, Nobumichi, Fujimoto, Kiyohide

“…Background. Although routine surveillance imaging to examine upper urinary tract urothelial cancer recurrence during follow-up of nonmuscle invasive bladder…”
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