Search Results - "Shimizu, Shiho"

Openable artificial intestinal tract device integrated with a permeable filter for evaluating drug permeation through cells by Konishi, Satoshi, Ishibashi, Shingo, Shimizu, Shiho, Watanabe, Keita, Abdalkader, Rodi, Fujita, Takuya

“…Organs-on-chips using cultured cells have been developed and applied for evaluating in vitro biological phenomena. We previously reported an openable…”
Get full text

Daily administration of Sake Lees (Sake Kasu) reduced psychophysical stress-induced hyperalgesia and Fos responses in the lumbar spinal dorsal horn evoked by noxious stimulation to the hindpaw in the rats by Shimizu, Shiho, Nakatani, Yosuke, Kakihara, Yoshito, Taiyoji, Mayumi, Saeki, Makio, Takagi, Ritsuo, Yamamura, Kensuke, Okamoto, Keiichiro

“…We tested whether Sake Lees (SL) had inhibitory effects on hyperalgesia in the hindpaw under psychophysical stress conditions. Male rats were subjected to…”
Get full text

Genomic analysis of a Streptomyces tsukubaensis mutant with reduced FR900525 production isolated by selection for S-(2-aminoethyl) l-cysteine resistance by Shimizu, Shiho, Futase, Ayako, Yokoyama, Tatsuya, Honda, Hiroyuki

“…FK506 (tacrolimus), a macrolide compound with immunosuppressant activity, has been shown to be of clinical importance and has been manufactured industrially…”
Get full text

Japanese Rice Wine can reduce psychophysical stress-induced depression-like behaviors and Fos expression in the trigeminal subnucleus caudalis evoked by masseter muscle injury in the rats by Nakatani, Yosuke, Kakihara, Yoshito, Shimizu, Shiho, Kurose, Masayuki, Sato, Tsutomu, Kaneoke, Mitsuoki, Saeki, Makio, Takagi, Ritsuo, Yamamura, Kensuke, Okamoto, Keiichiro

“…We determined if Japanese Rice Wine (Sake) had inhibitory effects on stress-induced enhancement of masseter muscle (MM) nociception in the rats. Male rats were…”
Get full text

Inhibitory effects of fluoxetine, an antidepressant drug, on masseter muscle nociception at the trigeminal subnucleus caudalis and upper cervical spinal cord regions in a rat model of psychophysical stress by Nakatani, Yosuke, Kurose, Masayuki, Shimizu, Shiho, Hasegawa, Mana, Ikeda, Nobuyuki, Yamamura, Kensuke, Takagi, Ritsuo, Okamoto, Keiichiro

“…This study aimed to determine whether psychophysical stress conditionings had facilitatory effects on masseter muscle nociception in the central nervous system…”
Get full text

Modulatory effects of repeated psychophysical stress on masseter muscle nociception in the nucleus raphe magnus of rats by Shimizu, Shiho, Nakatani, Yosuke, Kurose, Masayuki, Imbe, Hiroki, Ikeda, Nobuyuki, Takagi, Ritsuo, Yamamura, Kensuke, Okamoto, Keiichiro

“…Psychophysical stress can cause neural changes that increase nociception in the orofacial region, particularly the masseter muscle (MM). The nucleus raphe…”
Get full text

Pilot-scale whole-cell biocatalysis for the hydroxylation of cyclosporine derivative, FR901459, at higher concentrations by Lentzea sp. 7887 using soybean flour as a novel substrate dispersant by Yabutani, Tetsuya, Shimizu, Shiho, Nakano, Hideo

“…Pilot-scale hydroxylation of FR901459, an immunosuppressive cyclosporine derivative, was performed using resting cells of a Gram-positive bacteria Lentzea sp…”
Get full text

Reduction of FR900525 using an S-(2-aminoethyl) l-cysteine-resistant mutant by Shimizu, Shiho, Futase, Ayako, Yokoyama, Tatsuya, Ueda, Satoshi, Honda, Hiroyuki

“…FK506 (tacrolimus), a macrolide compound with immunosuppressant activity, has been proven to have clinical importance and has been manufactured industrially…”
Get full text

Openable Double‐Microtube Structure Driven by Pneumatic Balloon Actuator Arrays for Tubular Organ‐on‐a‐Chip by Shimizu, Shiho, Nishizaki, Keiichiro, Konishi, Satoshi

“…Microfluidic platforms have revolutionized research in biomedical engineering, enabling efficient and controlled experimentation. Here, we present a novel…”
Get full text

Improvement of FR901379 production by mutant selection and medium optimization by Kanda, Munekazu, Tsuboi, Masaru, Sakamoto, Kazutoshi, Shimizu, Shiho, Yamashita, Michio, Honda, Hiroyuki

“…FR901379 (WF11899A) is a novel echinocandin type of lipopeptide antibiotic produced by Coleophoma empetri F-11899. Micafungin (FK463) is derived from the…”
Get full text

Strain improvement of Lentzea sp. 7887 for higher yield per unit volume on hydroxylation of cyclosporine derivative FR901459 by Yabutani, Tetsuya, Tsujimoto, Mami, Ohira, Shunsuke, Shimizu, Shiho, Nakano, Hideo

“…A Gram-positive bacterium Lentzea sp. 7887 hydroxylates a cyclosporine derivative FR901459 into AS1837812 (9-hydroxide), which is an important intermediate of…”
Get full text

Rapid Evaluation of the Bioremediation of Fuel Oil in Soil by Gas Chromatography-Laser Ionization Time-of-Flight Mass Spectrometry by Miyagawa, Tomomi, Shimizu, Shiho, Miura, Asa, Fukuyama, Atsuko, Uchimura, Tomohiro

“…Gas chromatography-laser ionization time-of-flight mass spectrometry (GC-LI-TOFMS) was applied to the analysis of fuel oil in soil and soil treated by…”
Get full text

Modulatory effects of repeated psychophysical stress on masseter muscle nociception in the nucleus raphe magnus of rats by Shimizu, Shiho, Nakatani, Yosuke, Kurose, Masayuki, Imbe, Hiroki, Ikeda, Nobuyuki, Takagi, Ritsuo, Yamamura, Kensuke, Okamoto, Keiichiro

“…Psychophysical stress can cause neural changes that increase nociception in the orofacial region, particularly the masseter muscle (MM). The nucleus raphe…”
Get full text

Openable Double-Microtube Structure Driven by Pneumatic Balloon Actuator Arrays for Tubular Organ-on-a-Chip by Shimizu, Shiho, Nishizaki, Keiichiro, Konishi, Satoshi

“…Microfluidic platforms have revolutionized research in biomedical engineering, enabling efficient and controlled experimentation. Here, we present a novel…”
Get full text

Strain selection and scale-up fermentation for FR901379 acylase production by Streptomyces sp. no. 6907 by Ueda, Satoshi, Kinoshita, Masayoshi, Tanaka, Fumihiro, Tsuboi, Masaru, Shimizu, Shiho, Oohata, Nobutaka, Hino, Motohiro, Yamada, Masato, Isogai, Yasuhiro, Hashimoto, Seiji

“…Micafungin (FK463) is a widely used treatment for life-threatening, deep-seated fungal infections. It is an echinocandin-like lipopeptide derived from the…”
Get full text