Search Results - "Shimazoe, Takao"

Dimethyl Fumarate Attenuates Oxaliplatin-Induced Peripheral Neuropathy without Affecting the Anti-tumor Activity of Oxaliplatin in Rodents by Miyagi, Anna, Kawashiri, Takehiro, Shimizu, Shiori, Shigematsu, Nao, Kobayashi, Daisuke, Shimazoe, Takao

“…Oxaliplatin has been used as a first choice for colorectal, gastric and pancreatic cancer, but it induces peripheral neuropathies. Dimethyl fumarate (DMF) is…”
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Anti-tumor Activities of 3-Hydroxy-3-methylglutaryl Coenzyme A (HMG-CoA) Reductase Inhibitors and Bisphosphonates in Pancreatic Cell Lines Which Show Poor Responses to Gemcitabine by Kawashiri, Takehiro, Tokunaga, Ayumi, Kobayashi, Daisuke, Shimazoe, Takao

“…Few therapeutic options exist for gemcitabine-resistant pancreatic cancer. In this study, we investigated the anti-cancer effects of 3-hydroxy-3-methylglutaryl…”
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Analgesic Effects of Sokeikakketsuto on Chemotherapy-Induced Mechanical Allodynia and Cold Hyperalgesia in Rats by Nakamura, Hiroko, Kawashiri, Takehiro, Kobayashi, Daisuke, Uchida, Mayako, Egashira, Nobuaki, Shimazoe, Takao

“…The anticancer agents including oxaliplatin, paclitaxel, and bortezomib cause severe peripheral neuropathy. The Kampo medicine Sokeikakketsuto (SOKT) has been…”
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Donepezil ameliorates oxaliplatin-induced peripheral neuropathy via a neuroprotective effect by Kawashiri, Takehiro, Shimizu, Shiori, Shigematsu, Nao, Kobayashi, Daisuke, Shimazoe, Takao

“…Oxaliplatin induces severe peripheral neuropathy. The effect of donepezil, a drug used for treatment of Alzheimer's disease, on oxaliplatin-induced peripheral…”
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Oral administration of Cystine and Theanine ameliorates oxaliplatin-induced chronic peripheral neuropathy in rodents by Kawashiri, Takehiro, Kobayashi, Daisuke, Egashira, Nobuaki, Tsuchiya, Takashi, Shimazoe, Takao

“…Oxaliplatin frequently causes severe peripheral neuropathy as a dose-limiting toxicity. However, this toxicity lacks a strategy for prevention…”
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Use of omeprazole, the proton pump inhibitor, as a potential therapy for the capecitabine-induced hand-foot syndrome by Hiromoto, Shiori, Kawashiri, Takehiro, Yamanaka, Natsumi, Kobayashi, Daisuke, Mine, Keisuke, Inoue, Mizuki, Uchida, Mayako, Shimazoe, Takao

“…Hand-foot syndrome (HFS), also known as palmar-plantar erythrodysesthesia (PPE), is a major side effect of capecitabine. Although the pathogenesis of HFS…”
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Neuroprotective effect of alogliptin on oxaliplatin-induced peripheral neuropathy in vivo and in vitro by Shigematsu, Nao, Kawashiri, Takehiro, Kobayashi, Daisuke, Shimizu, Shiori, Mine, Keisuke, Hiromoto, Shiori, Uchida, Mayako, Egashira, Nobuaki, Shimazoe, Takao

“…Oxaliplatin is a platinum-based antineoplastic drug commonly used for treating colorectal, gastric, and pancreatic cancer. However, it frequently causes…”
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Mechanisms and Safety of Antidepressant-Like Effect of Nutmeg in Mice by Iwata, Naohiro, Kobayashi, Daisuke, Kawashiri, Takehiro, Kubota, Toshio, Kawano, Kotomi, Yamamuro, Yuki, Miyagi, Anna, Deguchi, Yuya, Chijimatsu, Takeshi, Shimazoe, Takao

“…Nutmeg, a dried seed kernel of a tall evergreen Myristicaceae tree, is widely used as a spice and herbal medicine and is known to have antidepressant-like…”
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Ameliorating effects of cystine and theanine in a cancer cachexia mouse model by Kudamatsu, Hibiki, Kawashiri, Takehiro, Mine, Keisuke, Mori, Kohei, Inoue, Mizuki, Ishida, Haruna, Uchida, Mayako, Tsuchiya, Takashi, Kobayashi, Daisuke, Shimazoe, Takao

“…Cachexia is a common cancer complication and is associated with weight loss and anorexia. In this study, we investigated the ameliorating effects of cystine…”
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Dimethyl fumarate ameliorates chemotherapy agent-induced neurotoxicity in vitro by Kawashiri, Takehiro, Miyagi, Anna, Shimizu, Shiori, Shigematsu, Nao, Kobayashi, Daisuke, Shimazoe, Takao

“…Chemotherapy agents such as oxaliplatin, cisplatin, paclitaxel, and bortezomib frequently cause severe peripheral neuropathy and there is currently no…”
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Preclinical and Clinical Evidence of Therapeutic Agents for Paclitaxel-Induced Peripheral Neuropathy by Kawashiri, Takehiro, Inoue, Mizuki, Mori, Kohei, Kobayashi, Daisuke, Mine, Keisuke, Ushio, Soichiro, Kudamatsu, Hibiki, Uchida, Mayako, Egashira, Nobuaki, Shimazoe, Takao

“…Paclitaxel is an essential drug in the chemotherapy of ovarian, non-small cell lung, breast, gastric, endometrial, and pancreatic cancers. However, it…”
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Therapeutic Agents for Oxaliplatin-Induced Peripheral Neuropathy; Experimental and Clinical Evidence by Kawashiri, Takehiro, Mine, Keisuke, Kobayashi, Daisuke, Inoue, Mizuki, Ushio, Soichiro, Uchida, Mayako, Egashira, Nobuaki, Shimazoe, Takao

“…Oxaliplatin is an essential drug in the chemotherapy of colorectal, gastric, and pancreatic cancers, but it frequently causes peripheral neuropathy as a…”
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Synergistic Antiproliferative Effects of Zoledronic Acid and Fluvastatin on Human Pancreatic Cancer Cell Lines: An in Vitro Study by Elsayed, Mahitab, Kobayashi, Daisuke, Kubota, Toshio, Matsunaga, Naoya, Murata, Ryusei, Yoshizawa, Yuko, Watanabe, Natsuki, Matsuura, Tohru, Tsurudome, Yuya, Ogino, Takashi, Ohdo, Shigehiro, Shimazoe, Takao

“…Bisphosphonates and statins are known to have antitumor activities against different types of cancer cell lines. In the present study, we investigated the…”
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Analysis of Secondary Leukemia and Myelodysplastic Syndrome After Chemotherapy for Solid Organ Tumors Using the Food and Drug Administration Adverse Event Reporting System (FAERS) by Kawashiri, Takehiro, Kobayashi, Daisuke, Uchida, Mayako, Hiromoto, Shiori, Inoue, Masashi, Ikeda, Hajime, Inoue, Mizuki, Shimazoe, Takao

“…As the prognosis of cancer patients deteriorates, secondary carcinogenesis after chemotherapy, especially secondary hematological malignancies, becomes a…”
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Omeprazole Suppresses Oxaliplatin-Induced Peripheral Neuropathy in a Rodent Model and Clinical Database by Mine, Keisuke, Kawashiri, Takehiro, Inoue, Mizuki, Kobayashi, Daisuke, Mori, Kohei, Hiromoto, Shiori, Kudamatsu, Hibiki, Uchida, Mayako, Egashira, Nobuaki, Koyanagi, Satoru, Ohdo, Shigehiro, Shimazoe, Takao

“…(1) Background: Oxaliplatin is used as first-line chemotherapy not only for colorectal cancer but also for gastric and pancreatic cancers. However, it induces…”
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Identification of prophylactic drugs for oxaliplatin-induced peripheral neuropathy using big data by Zamami, Yoshito, Niimura, Takahiro, Kawashiri, Takehiro, Goda, Mitsuhiro, Naito, Yutaro, Fukushima, Keijo, Ushio, Soichiro, Aizawa, Fuka, Hamano, Hirofumi, Okada, Naoto, Yagi, Kenta, Miyata, Koji, Takechi, Kenshi, Chuma, Masayuki, Koyama, Toshihiro, Kobayashi, Daisuke, Shimazoe, Takao, Fujino, Hiromichi, Izawa-Ishizawa, Yuki, Ishizawa, Keisuke

“…Drug repositioning is a cost-effective method to identify novel disease indications for approved drugs; it requires a shorter developmental period than…”
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Effects on Deaf Patients of Medication Education by Pharmacists by Hyoguchi, Naomi, Kobayashi, Daisuke, Kubota, Toshio, Shimazoe, Takao

“…Deaf people often experience difficulty in understanding medication information provided by pharmacists due to communication barriers. We held medication…”
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Need for Prescription Suggestions for Long-term Inpatients in the Psychiatric Ward by Shin, Kenji, Kobayashi, Daisuke, Kawashiri, Takehiro, Ushijima, Yuichi, Moritaka, Keita, Yanai, Hiroshi, Ichiki, Yuko, Murakami, Aya, Kanazawa, Yasunori, Kamimura, Hidetoshi, Shimazoe, Takao

“…Additional fees for ward pharmacists' services have been valued for hospitals in Japan. However, the calculation period for services provided to inpatients in…”
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Maternal exposure to dioxin imprints sexual immaturity of the pups through fixing the status of the reduced expression of hypothalamic gonadotropin-releasing hormone by Takeda, Tomoki, Fujii, Misaki, Hattori, Yukiko, Yamamoto, Midori, Shimazoe, Takao, Ishii, Yuji, Himeno, Masaru, Yamada, Hideyuki

“…Our previous studies have shown that treatment of pregnant rats with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD; 1 μg/kg) at gestational day (GD) 15 reduces the…”
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Medical Opioid Disposal in Fukuoka and Kumamoto Cities by Ota, Asami, Kurata, Shinnosuke, Tatsuma, Kaho, Isaka, Hinako, Higuchi, Yoshinori, Nishina, Takeshi, Haraguchi, Keiko, Takaki, Junichi, Kihara, Taro, Tanaka, Taizo, Amagata, Tomoko, Inaba, Ichiro, Kawashiri, Takehiro, Kobayashi, Daisuke, Shimazoe, Takao

“…Medical expenses are increasing year by year in Japan. However, the quantity of disposed medical opioids is not well known. In this study, we assessed disposed…”
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