Search Results - "Shimasaki, Ayu"

Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect by Ikeda, Masashi, Takahashi, Atsushi, Kamatani, Yoichiro, Momozawa, Yukihide, Saito, Takeo, Kondo, Kenji, Shimasaki, Ayu, Kawase, Kohei, Sakusabe, Takaya, Iwayama, Yoshimi, Toyota, Tomoko, Wakuda, Tomoyasu, Kikuchi, Mitsuru, Kanahara, Nobuhisa, Yamamori, Hidenaga, Yasuda, Yuka, Watanabe, Yuichiro, Hoya, Satoshi, Aleksic, Branko, Kushima, Itaru, Arai, Heii, Takaki, Manabu, Hattori, Kotaro, Kunugi, Hiroshi, Okahisa, Yuko, Ohnuma, Tohru, Ozaki, Norio, Someya, Toshiyuki, Hashimoto, Ryota, Yoshikawa, Takeo, Kubo, Michiaki, Iwata, Nakao

“…Genome-wide association studies (GWASs) have identified >100 susceptibility loci for schizophrenia (SCZ) and demonstrated that SCZ is a polygenic disorder…”
Get full text

Shared genetic components between metabolic syndrome and schizophrenia: Genetic correlation using multipopulation data sets by Aoki, Rei, Saito, Takeo, Ninomiya, Kohei, Shimasaki, Ayu, Ashizawa, Takuma, Ito, Kenta, Ikeda, Masashi, Iwata, Nakao

“…Aim The genetic relationship between schizophrenia (SCZ) and other nonpsychiatric disorders remains largely unknown. We examined the shared genetic components…”
Get full text

Cost effectiveness of pharmacogenetic-guided clozapine administration based on risk of HLA variants in Japan and the UK by Ninomiya, Kohei, Saito, Takeo, Okochi, Tomo, Taniguchi, Satoru, Shimasaki, Ayu, Aoki, Rei, Hata, Takeo, Mushiroda, Taisei, Kanazawa, Tetsufumi, Ikeda, Masashi, Iwata, Nakao

“…Pharmacogenetics/pharmacogenomics have enabled the detection of risk of human leukocyte antigen (HLA) variants for clozapine-induced…”
Get full text

Pharmacogenomic Study of Clozapine-Induced Agranulocytosis/Granulocytopenia in a Japanese Population by Saito, Takeo, Ikeda, Masashi, Mushiroda, Taisei, Ozeki, Takeshi, Kondo, Kenji, Shimasaki, Ayu, Kawase, Kohei, Hashimoto, Shuji, Yamamori, Hidenaga, Yasuda, Yuka, Fujimoto, Michiko, Ohi, Kazutaka, Takeda, Masatoshi, Kamatani, Yoichiro, Numata, Shusuke, Ohmori, Tetsuro, Ueno, Shu-ichi, Makinodan, Manabu, Nishihata, Yosuke, Kubota, Masaharu, Kimura, Takemi, Kanahara, Nobuhisa, Hashimoto, Naoki, Fujita, Kiyoshi, Nemoto, Kiyotaka, Fukao, Taku, Suwa, Taro, Noda, Tetsuro, Yada, Yuji, Takaki, Manabu, Kida, Naoya, Otsuru, Taku, Murakami, Masaru, Takahashi, Atsushi, Kubo, Michiaki, Hashimoto, Ryota, Iwata, Nakao

“…Abstract Background Clozapine-induced agranulocytosis (CIA)/clozapine-induced granulocytopenia (CIG) (CIAG) is a life-threatening event for schizophrenic…”
Get full text

Effect of a brief cognitive behavioral program on depressive symptoms among newly licensed registered nurses: An observational study by Esaki, Kosei, Ikeda, Masashi, Okochi, Tomo, Taniguchi, Satoru, Ninomiya, Kohei, Shimasaki, Ayu, Otsuka, Yasuyo, Oda, Yoshiko, Sakusabe, Takaya, Mano, Keiko, Saito, Takeo, Iwata, Nakao

“…Depressive symptoms are a serious problem in workplaces. Hospital staff members, such as newly licensed registered nurses (NLRNs), are at particularly…”
Get full text

Polygenic risk scores in schizophrenia with clinically significant copy number variants by Taniguchi, Satoru, Ninomiya, Kohei, Kushima, Itaru, Saito, Takeo, Shimasaki, Ayu, Sakusabe, Takaya, Momozawa, Yukihide, Kubo, Michiaki, Kamatani, Yoichiro, Ozaki, Norio, Ikeda, Masashi, Iwata, Nakao

“…Aims Recent studies have revealed that the interplay between polygenic risk scores (PRS) and large copy number variants (CNV; >500kb) is essential for the…”
Get full text

A genetic variant in 12q13, a possible risk factor for bipolar disorder, is associated with depressive state, accounting for stressful life events by Shimasaki, Ayu, Kondo, Kenji, Saito, Takeo, Esaki, Kosei, Otsuka, Yasuyo, Mano, Keiko, Ikeda, Masashi, Iwata, Nakao

“…Genome-wide association studies (GWASs) have identified a number of susceptibility genes for schizophrenia (SCZ) and bipolar disorder (BD). However, the…”
Get full text

Risk factors and clinical characteristics of the depressive state induced by pegylated interferon therapy in patients with hepatitis C virus infection: A prospective study by Kawase, Kohei, Kondo, Kenji, Saito, Takeo, Shimasaki, Ayu, Takahashi, Atsushi, Kamatani, Yoichiro, Kawabe, Naoto, Hashimoto, Senju, Ikeda, Masashi, Kubo, Michiaki, Yoshioka, Kentaro, Iwata, Nakao

“…Aim Pegylated interferon (PegIFN) therapies for hepatitis C virus (HCV) infection often induce a depressive state. This study aimed to identify the risk…”
Get full text

No support for replication of the genetic variants identified by a recent mega-analysis of the treatment response to antidepressants by Hatano, Masakazu, Ikeda, Masashi, Kondo, Kenji, Saito, Takeo, Shimasaki, Ayu, Esaki, Kosei, Umene-Nakano, Wakako, Yoshimura, Reiji, Nakamura, Jun, Ozaki, Norio, Iwata, Nakao

Get full text

Genome-wide environment interaction between depressive state and stressful life events by Ikeda, Masashi, Shimasaki, Ayu, Takahashi, Atsushi, Kondo, Kenji, Saito, Takeo, Kawase, Kohei, Esaki, Kosei, Otsuka, Yasuyo, Mano, Keiko, Kubo, Michiaki, Iwata, Nakao

Get full text

M84 POLYGENIC RISK SCORES IN SCHIZOPHRENIA WITH CLINICALLY SIGNIFICANT COPY NUMBER VARIANTS by Taniguchi, Satoru, Ninomiya, Kohei, Kushima, Itaru, Okochi, Tomo, Saito, Takeo, Shimasaki, Ayu, Sakusabe, Takaya, Momozawa, Yukihide, Kubo, Michiaki, Kamatani, Yoichiro, Ozaki, Norio, Ikeda, Masashi, Iwata, Nakao

Get full text

Replication and cross-phenotype study based upon schizophrenia GWASs data in the Japanese population: Support for association of MHC region with psychosis by Saito, Takeo, Kondo, Kenji, Iwayama, Yoshimi, Shimasaki, Ayu, Aleksic, Branko, Yamada, Kazuo, Toyota, Tomoko, Hattori, Eiji, Esaki, Kosei, Ujike, Hiroshi, Inada, Toshiya, Kunugi, Hiroshi, Kato, Tadafumi, Yoshikawa, Takeo, Ozaki, Norio, Ikeda, Masashi, Iwata, Nakao

“…Recent genome‐wide association studies (GWASs) of schizophrenia (SCZ) identified several susceptibility genes and suggested shared genetic components between…”
Get full text

Rare truncating variations and risk of schizophrenia: Whole-exome sequencing in three families with affected siblings and a three-stage follow-up study in a Japanese population by Watanabe, Yuichiro, Nunokawa, Ayako, Shibuya, Masako, Ikeda, Masashi, Hishimoto, Akitoyo, Kondo, Kenji, Egawa, Jun, Kaneko, Naoshi, Muratake, Tatsuyuki, Saito, Takeo, Okazaki, Satoshi, Shimasaki, Ayu, Igeta, Hirofumi, Inoue, Emiko, Hoya, Satoshi, Sugai, Takuro, Sora, Ichiro, Iwata, Nakao, Someya, Toshiyuki

“…Abstract Rare inherited variations in multiplex families with schizophrenia are suggested to play a role in the genetic etiology of schizophrenia. To further…”
Get full text

Transethnic Replication Study to Assess the Association Between Clozapine-Induced Agranulocytosis/Granulocytopenia and Genes at 12p12.2 in a Japanese Population by Saito, Takeo, Ikeda, Masashi, Hashimoto, Ryota, Iwata, Nakao, Yamamori, Hidenaga, M.D, Ph.D, Yasuda, Yuka, M.D, PhD, Fujimoto, Michiko, M.D, PhD, Kondo, Kenji, M.D., Ph.D, Shimasaki, Ayu, M.D., Ph.D, Kawase, Kohei, M.D, Miyata, Masami, Mushiroda, Taisei, Ph.D, Ozeki, Takeshi, Ph.D, Kubo, Michiaki, M.D., Ph.D, Fujita, Kiyoshi, M.D., Ph.D, Kida, Naoya, M.D, Nakai, Minori, M.D, Otsuru, Taku, M.D, Fukuji, Yasuhide, M.D, Murakami, Masaru, M.D, Mizuno, Kentaro, M.D, Shiratsuchi, Toshiaki, M.D, Numata, Shusuke, M.D, Ph.D, Ohmori, Tetsuro, M.D., Ph.D, Ueno, Shu-ichi, M.D., Ph.D, Yada, Yuji, M.D, Tanaka, Sadakazu, M.D, Kishi, Yoshiki, M.D, Takaki, Manabu, M.D., Ph.D, Mamoto, Akiko, M.D., Ph.D, Taniguchi, Norio, M.D., Ph.D, Sawa, Yutaka, M.D, Watanabe, Haruo, M.D, Noda, Tetsuro, M.D., Ph.D, Amano, Yuuhei, M.D, Kimura, Takemi, M.D., Ph.D, Fukao, Taku, M.D, Suwa, Taro, M.D., Ph.D, Murai, Toshiya, M.D., Ph.D, Kubota, Masaharu, M.D., Ph.D, Ueda, Keishi, M.D, Tabuse, Hideaki, M.D, Kanahara, Nobuhisa, M.D., Ph.D, Kawai, Nobutoshi, M.D., Ph.D, Nemoto, Kiyotaka, M.D., Ph.D, Makinodan, Manabu, M.D., Ph.D, Nishihata, Yosuke, M.D, Hashimoto, Naoki, M.D, Ph.D, Kusumi, Ichiro, M.D., Ph.D, Fujii, Yasuo, Ph.D., M.D, Miyata, Ryoji, M.D, Hirakawa, Kyuryoku, M.D, Ozaki, Norio, M.D., Ph.D

Get full text

Genetic overlap between antipsychotic response and susceptibility to schizophrenia by Ikeda, Masashi, Yoshimura, Reiji, Hashimoto, Ryota, Kondo, Kenji, Saito, Takeo, Shimasaki, Ayu, Ohi, Kazutaka, Tochigi, Mamoru, Kawamura, Yoshiya, Nishida, Nao, Miyagawa, Taku, Sasaki, Tsukasa, Tokunaga, Katsushi, Kasai, Kiyoto, Takeda, Masatoshi, Nakamura, Jun, Ozaki, Norio, Iwata, Nakao

Get full text

A Genetic Variant in 12q13, a Possible Risk Factor for Bipolar Disorder, Is Associated with Depressive State, Accounting for Stressful Life Events: e115135 by Shimasaki, Ayu, Kondo, Kenji, Saito, Takeo, Esaki, Kosei, Otsuka, Yasuyo, Mano, Keiko, Ikeda, Masashi, Iwata, Nakao

“…Genome-wide association studies (GWASs) have identified a number of susceptibility genes for schizophrenia (SCZ) and bipolar disorder (BD). However, the…”
Get full text