Search Results - "Shimamura, Sanae"
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Ectopic RASGRP2 (CalDAG-GEFI) expression in rheumatoid synovium contributes to the development of destructive arthritis
Published in Annals of the rheumatic diseases (01-12-2018)“…Rheumatoid arthritis (RA) is an autoimmune polyarthritis, in which fibroblast-like synoviocytes (FLS) play a key role in cartilage and bone destruction through…”
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Three Cases of Intravascular Large B-Cell Lymphoma Detected in a Biopsy of Skin Lesions
Published in Dermatology (Basel) (01-01-2016)“…Intravascular large B-cell lymphoma (IVL) is a rare subtype of extranodal malignant lymphoma. The proliferation of neoplastic B cells within small blood…”
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Saddle nose with sarcoidosis: "A great imitator" of relapsing polychondritis
Published in Modern rheumatology (02-11-2018)“…Sarcoidosis is a systemic granulomatous disease that can affect any organ including the nose. Nasal crusting and congestion are common nasal symptoms of…”
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Interferon-inducible Mx1 protein is highly expressed in renal tissues from treatment-naïve lupus nephritis, but not in those under immunosuppressive treatment
Published in Modern rheumatology (04-07-2018)“…Objectives: The aim of this study was to clarify the consequences of Mx1, one of the IFN-inducible proteins, in the peripheral blood as well as in renal…”
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Clinical significance of plasma presepsin levels in patients with systemic lupus erythematosus
Published in Modern rheumatology (03-09-2018)“…Objectives: Presepsin (PSEP: soluble CD14 subtype) is produced from bacteria-stimulated monocytes or neutrophils, thus recognized as a biomarker of sepsis…”
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Surveillance for the use of mycophenolate mofetil for adult patients with lupus nephritis in Japan
Published in Modern rheumatology (01-01-2015)“…Objectives. Mycophenolate mofetil (MMF) is used as one of the standard induction/maintenance protocols for lupus nephritis (LN). However, MMF has not been…”
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A national survey on current use of mycophenolate mofetil for childhood-onset systemic lupus erythematosus in Japan
Published in Modern rheumatology (01-01-2015)“…Purpose. To conduct a national survey of systemic lupus erythematosus (SLE) patients treated with mycophenolate mofetil (MMF). Based on current information on…”
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MicroRNA-9 ameliorates destructive arthritis through down-regulation of NF-κB1-RANKL pathway in fibroblast-like synoviocytes
Published in Clinical immunology (Orlando, Fla.) (01-03-2020)“…We investigated the effect of miR-9 on fibroblast-like synoviocytes (FLS) from RA patients and animal arthritis model. The binding of miR-9 to NF-κB1 3’UTR was…”
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Post-steroid neuropsychiatric manifestations are significantly more frequent in SLE compared with other systemic autoimmune diseases and predict better prognosis compared with de novo neuropsychiatric SLE
Published in Autoimmunity reviews (01-08-2016)“…Abstract In patients with systemic lupus erythematosus (SLE), neuropsychiatric (NP) symptoms sometimes occur after administration of corticosteroids, making…”
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Prognosis and progress in immunotherapies for organ involvements in systemic autoimmune diseases
Published in Nihon Rinshō Menʾeki Gakkai kaishi (2016)“…Treatment of organ involvements accompanied by systemic autoimmune diseases is still challenging for clinicians, reminding the existence of unmet needs. Among…”
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Modulation by polyamines of DNA-dependent DNA polymerase activity from human serum
Published in International journal of biochemistry (1990)“…1. Spermine, spermidine and putrescine activated DNA-dependent DNA polymerase from human sera by 47-125% at the concentrations of 0.2, 3 and 30 mM,…”
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