Search Results - "Shimamura, Kenji"

The Pace of Neurogenesis Is Regulated by the Transient Retention of the Apical Endfeet of Differentiating Cells by Hatakeyama, Jun, Shimamura, Kenji

“…The development of the mammalian cerebral cortex involves a variety of temporally organized events such as successive waves of neuronal production and the…”
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Thalamocortical axons control the cytoarchitecture of neocortical layers by area-specific supply of VGF by Sato, Haruka, Hatakeyama, Jun, Iwasato, Takuji, Araki, Kimi, Yamamoto, Nobuhiko, Shimamura, Kenji

“…Neuronal abundance and thickness of each cortical layer are specific to each area, but how this fundamental feature arises during development remains poorly…”
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Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates by Hatakeyama, Jun, Wakamatsu, Yoshio, Nagafuchi, Akira, Kageyama, Ryoichiro, Shigemoto, Ryuichi, Shimamura, Kenji

“…The development of the vertebrate brain requires an exquisite balance between proliferation and differentiation of neural progenitors. Notch signaling plays a…”
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Formation of dorsal–ventral axis of the pallium derived from mouse embryonic stem cells by Nasu, Makoto, Shimamura, Kenji, Esumi, Shigeyuki, Tamamaki, Nobuaki

“…The telencephalon is one of the most-elaborated tissues. A broad variety of cell types is produced by spatiotemporally regulated mechanisms and is involved, in…”
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VCAM1-α4β1 integrin interaction mediates interstitial tissue reconstruction in 3-D re-aggregate culture of dissociated prepubertal mouse testicular cells by Abe, Kazuko, Kon, Shigeyuki, Kameyama, Hiroki, Zhang, JiDong, Morohashi, Ken-ichirou, Shimamura, Kenji, Abe, Shin-ichi

“…Roles of interstitial tissue in morphogenesis of testicular structures remain less well understood. To analyze the roles of CD34 + cells in the reconstruction…”
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Sequential pattern of sublayer formation in the paleocortex and neocortex by Nasu, Makoto, Shimamura, Kenji, Esumi, Shigeyuki, Tamamaki, Nobuaki

“…The piriform cortex (paleocortex) is the olfactory cortex or the primary cortex for the sense of smell. It receives the olfactory input from the mitral and…”
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Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria by Nagahara, Noriyuki, Nagano, Masatoshi, Ito, Takaaki, Shimamura, Kenji, Akimoto, Toshio, Suzuki, Hidenori

“…Human mercaptolactate-cysteine disulfiduria (MCDU) was first recognized and reported in 1968. Most cases of MCDU are associated with mental retardation, while…”
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Developing guinea pig brain as a model for cortical folding by Hatakeyama, Jun, Sato, Haruka, Shimamura, Kenji

“…The cerebral cortex in mammals, the neocortex specifically, is highly diverse among species with respect to its size and morphology, likely reflecting the…”
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Thalamus-derived molecules promote survival and dendritic growth of developing cortical neurons by Sato, Haruka, Fukutani, Yuma, Yamamoto, Yuji, Tatara, Eiichi, Takemoto, Makoto, Shimamura, Kenji, Yamamoto, Nobuhiko

“…The mammalian neocortex is composed of various types of neurons that reflect its laminar and area structures. It has been suggested that not only intrinsic but…”
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Dysfunction of the proteoglycan Tsukushi causes hydrocephalus through altered neurogenesis in the subventricular zone in mice by Ito, Naofumi, Riyadh, M Asrafuzzaman, Ahmad, Shah Adil Ishtiyaq, Hattori, Satoko, Kanemura, Yonehiro, Kiyonari, Hiroshi, Abe, Takaya, Furuta, Yasuhide, Shinmyo, Yohei, Kaneko, Naoko, Hirota, Yuki, Lupo, Giuseppe, Hatakeyama, Jun, Abdulhaleem M, Felemban Athary, Anam, Mohammad Badrul, Yamaguchi, Masahiro, Takeo, Toru, Takebayashi, Hirohide, Takebayashi, Minoru, Oike, Yuichi, Nakagata, Naomi, Shimamura, Kenji, Holtzman, Michael J, Takahashi, Yoshiko, Guillemot, Francois, Miyakawa, Tsuyoshi, Sawamoto, Kazunobu, Ohta, Kunimasa

“…The lateral ventricle (LV) is flanked by the subventricular zone (SVZ), a neural stem cell (NSC) niche rich in extrinsic growth factors regulating NSC…”
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Roles of CD34+ cells and ALK5 signaling in the reconstruction of seminiferous tubule-like structures in 3-D re-aggregate culture of dissociated cells from neonatal mouse testes by Abe, Shin-Ichi, Abe, Kazuko, Zhang, Jidong, Harada, Tomoaki, Mizumoto, Go, Oshikawa, Hiroki, Akiyama, Haruhiko, Shimamura, Kenji

“…Tissue reconstruction in vitro can provide, if successful, a refined and simple system to analyze the underlying mechanisms that drive the morphogenesis and…”
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Two-Phase Lineage Specification of Telencephalon Progenitors Generated From Mouse Embryonic Stem Cells by Nasu, Makoto, Esumi, Shigeyuki, Hatakeyama, Jun, Tamamaki, Nobuaki, Shimamura, Kenji

“…Proper brain development requires precisely controlled phases of stem cell proliferation, lineage specification, differentiation, and migration. Lineage…”
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Tsukushi proteoglycan maintains RNA splicing and developmental signaling network in GFAP-expressing subventricular zone neural stem/progenitor cells by Istiaq, Arif, Umemoto, Terumasa, Ito, Naofumi, Suda, Toshio, Shimamura, Kenji, Ohta, Kunimasa

“…Tsukushi (TSK) proteoglycan dysfunction leads to hydrocephalus, a condition defined by excessive fluid collection in the ventricles and lateral ventricular…”
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Pallial and subpallial derivatives in the embryonic chick and mouse telencephalon, traced by the expression of the genes Dlx-2, Emx-1, Nkx-2.1, Pax-6, and Tbr-1 by Puelles, Luis, Kuwana, Ellen, Puelles, Eduardo, Bulfone, Alessandro, Shimamura, Kenji, Keleher, Jerry, Smiga, Susan, Rubenstein, John L.R.

“…Pallial and subpallial morphological subdivisions of the developing chicken telencephalon were examined by means of gene markers, compared with their…”
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The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina by Ha, Taejeong, Moon, Kyeong Hwan, Dai, Le, Hatakeyama, Jun, Yoon, Keejung, Park, Hee-Sae, Kong, Young-Yoon, Shimamura, Kenji, Kim, Jin Woo

“…Notch signaling in neural progenitor cell is triggered by ligands expressed in adjacent cells. To identify the sources of active Notch ligands in the mouse…”
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Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development by Lagutin, Oleg V, Zhu, Changqi C, Kobayashi, Daisuke, Topczewski, Jacek, Shimamura, Kenji, Puelles, Luis, Russell, Helen R C, McKinnon, Peter J, Solnica-Krezel, Lilianna, Oliver, Guillermo

“…In vertebrate embryos, formation of anterior neural structures requires suppression of Wnt signals emanating from the paraxial mesoderm and midbrain territory…”
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Development of the prethalamus is crucial for thalamocortical projection formation and is regulated by Olig2 by Ono, Katsuhiko, Clavairoly, Adrien, Nomura, Tadashi, Gotoh, Hitoshi, Uno, Aoi, Armant, Olivier, Takebayashi, Hirohide, Zhang, Qi, Shimamura, Kenji, Itohara, Shigeyoshi, Parras, Carlos M, Ikenaka, Kazuhiro

“…Thalamocortical axons (TCAs) pass through the prethalamus in the first step of their neural circuit formation. Although it has been supposed that the…”
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Combinatorial Roles of Olig2 and Neurogenin2 in the Coordinated Induction of Pan-Neuronal and Subtype-Specific Properties of Motoneurons by Mizuguchi, Rumiko, Sugimori, Michiya, Takebayashi, Hirohide, Kosako, Hidetaka, Nagao, Motoshi, Yoshida, Shosei, Nabeshima, Yo-ichi, Shimamura, Kenji, Nakafuku, Masato

“…Distinct classes of neurons are generated at defined times and positions during development of the nervous system. It remains elusive how specification of…”
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Inductive interactions direct early regionalization of the mouse forebrain by Shimamura, K, Rubenstein, J L

“…The cellular and molecular mechanisms that regulate regional specification of the forebrain are largely unknown. We studied the expression of transcription…”
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Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice by Acebedo, Alvin R., Suzuki, Kentaro, Hino, Shinjiro, Alcantara, Mellissa C., Sato, Yuki, Haga, Hisashi, Matsumoto, Ken-ichi, Nakao, Mitsuyoshi, Shimamura, Kenji, Takeo, Toru, Nakagata, Naomi, Miyagawa, Shinichi, Nishinakamura, Ryuichi, Adelstein, Robert S., Yamada, Gen

“…The morphogenesis of mammalian embryonic external genitalia (eExG) shows dynamic differences between males and females. In genotypic males, eExG are…”
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