Search Results - "Shim, Wang‐Seob"

Development of a Rapid LC-MS/MS Method for Simultaneous Quantification of Donepezil and Tadalafil in Rat Plasma: Its Application in a Pharmacokinetic Interaction Study after Oral Administration in Rats by Yoon, Jiyoung, Choi, Doowon, Shim, Wang-Seob, Choi, Sanghee, Choi, Yeo Jin, Paik, Soo-Heui, Lee, Kyung-Tae

“…This study aimed to establish a simple and sensitive analytical method to simultaneously quantify donepezil (DPZ) and tadalafil (TAD) in rat plasma using…”
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A Pharmacokinetic Study of Ephedrine and Pseudoephedrine after Oral Administration of Ojeok-San by Validated LC-MS/MS Method in Human Plasma by Lee, Sooyoung, Shim, Wang-Seob, Yoo, Heejo, Choi, Sanghee, Yoon, Jiyoung, Lee, Kwang-Young, Chung, Eun-Kyoung, Lee, Byung-Cheol, Yim, Sung-Vin, Kim, Bo-Hyung, Lee, Kyung-Tae

“…A sensitive and reproducible liquid chromatography-tandem mass spectrometry (LC-MS/MS) system was developed and fully validated for the simultaneous…”
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A Validated Chiral LC-MS/MS Method for the Enantioselective Determination of (S)-(+)- and (R)-(-)-Ibuprofen in Dog Plasma: Its Application to a Pharmacokinetic Study by Choi, Sanghee, Shim, Wang-Seob, Yoon, Jiyoung, Choi, Doowon, Lee, Jinseong, Paik, Soo-Heui, Chung, Eun-Kyoung, Lee, Kyung-Tae

“…The purpose of this study was to develop a method for simultaneously separating ibuprofen enantiomers using electrospray ionization (ESI) liquid chromatography…”
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Development and Validation of an LC-MS/MS Assay to Quantitate 2',4',6'-Trihydroxyacetophenone in Rat and Dog Plasma and its Application to a Pharmacokinetic Study by Yoo, Hee Jo, Hwang, Se-Jung, Lee, Jeong-Hun, Shim, Wang-Seob, Choi, Yun-Woong, Cho, Sang Min, Chung, Eun Kyoung, Park, Jun-Bom, Lee, Kyung-Tae

“…In the present study, a simple, rapid, and reliable bioanalytical method was developed using liquid chromatography with tandem-mass spectrometry (LC-MS/MS) to…”
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Ginsenoside Absorption Rate and Extent Enhancement of Black Ginseng (CJ EnerG) over Red Ginseng in Healthy Adults by Yoo, Saebyul, Park, Bom-I, Kim, Do-Hyun, Lee, Sooyoung, Lee, Seung-Hoon, Shim, Wang-Seob, Seo, Yong Ki, Kang, Kimoon, Lee, Kyung-Tae, Yim, Sung-Vin, Soung, Do Yu, Kim, Bo-Hyung

“…Red ginseng (RG) and black ginseng (BG, CJ EnerG) were prepared from fresh ginseng using one and nine cycles of steaming and drying, respectively. This process…”
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Quantitation of plasma and biliary cefpiramide concentrations in human samples using high‐performance liquid chromatography by Yoon, Jimin, Kwack, Won Gun, Shim, Wang‐Seob, Lee, Jun Kyu, Jang, Dong Kee, Gu, Namyi, Cho, Ji‐Yoon, Lee, Kyung‐Tae, Chung, Eun Kyoung

“…Cefpiramide is frequently used to treat biliary infections. However, no bioanalytical method has been validated to quantitate cefpiramide in human samples,…”
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Method Development and Validation for the Simultaneous Quantitation of Pentoxifylline, Its Pharmacologically Active Metabolites, and Donepezil Using LC-MS/MS in Rat Plasma: Its Application to a Pharmacokinetic Study by Choi, Sanghee, Shim, Wang-Seob, Yoon, Jiyoung, Choi, Doowon, Song, Eunseo, Choi, Yeo Jin, Paik, Soo-Heui, Lee, Kyung-Tae

“…This study developed a simple, rapid, reproducible, and analytical method using liquid chromatography and electrospray ionization (ESI) with tandem mass…”
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Pharmacokinetics and bioequivalence of two fenofibrate choline formulations in healthy subjects under fed and fasted condition by Park, Ji-Min, Chae, Soo-In, Noh, Young Su, Lee, Seung-Jun, Shim, Wang-Seob, Yoon, Ji-Min, Hwang, Se Jung, Lee, Kyung-Tae, Chung, Eun Kyoung

“…The objective of this study was to evaluate the pharmacokinetics and bioequivalence of two formulations (the original capsule ("reference") and the new tablet…”
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Enhanced Absorption Study of Ginsenoside Compound K (20-O-β-(D-Glucopyranosyl)-20(S)-protopanaxadiol) after Oral Administration of Fermented Red Ginseng Extract (HYFRG™) in Healthy Korean Volunteers and Rats by Yim, Sung-Vin, Chung, Eun-Kyoung, Lee, Kyung-Tae, Huh, Chul-Sung, Sim, Jae-Hun, Ahn, Young-Tae, Shim, Jae-Joong, Lee, Myoung-Hee, Lee, Dong-Eun, Ryu, Ju-Hee, Choi, Il-Dong, Shim, Wang-Seob

“…To evaluate the pharmacokinetics of compound K after oral administration of HYFRG and RG in humans, an open-label, randomized, single-dose, fasting, and…”
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Pharmacokinetic and bioequivalence study comparing a fimasartan/rosuvastatin fixed-dose combination with the concomitant administration of fimasartan and rosuvastatin in healthy subjects by Kang, Woo Youl, Seong, Sook Jin, Ohk, Boram, Gwon, Mi-Ri, Kim, Bo Kyung, Cho, Seungil, Shim, Wang-Seob, Lee, Kyung-Tae, Kim, Eun Hee, Yang, Dong Heon, Lee, Hae Won, Yoon, Young-Ran

“…A new fixed-dose combination (FDC) formulation of 120 mg fimasartan and 20 mg rosuvastatin was developed to increase therapeutic convenience and improve…”
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Development of a Simple and Validated LC-MS/MS Method for Quantitative Determination of Ketotifen in Beagle Dog Plasma and Its Application to Bioequivalence Study of Ketotifen Syrup Dosage Form by Song, Eunseo, Shim, Wang-Seob, Choi, Doowon, Song, Yuna, Jo, Hyeong Geun, Lee, Soobok, Jung, Suk Han, Choi, Yeo Jin, Lee, Kyung-Tae

“…A highly accurate, precise, and simple liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for ketotifen (KTF) estimation from Beagle dog plasma…”
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Quantification of metronidazole in human bile fluid and plasma by liquid chromatography-tandem mass spectrometry by Yoon, Jimin, Kang, Sung Wook, Shim, Wang-Seob, Lee, Jun Kyu, Jang, Dong Kee, Gu, Namyi, Kim, Sae Kyul, Lee, Kyung-Tae, Chung, Eun Kyoung

“…•An LC-MS/MS method was developed for metronidazole in human samples.•Our newly developed method quantified metronidazole in plasma and bile samples.•The…”
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Development and Validation of an Improved HPLC-MS/MS Method for Quantifying Total and Unbound Lenalidomide in Human Plasma by Lee, Suhyun, Yang, Seungwon, Shim, Wang-Seob, Song, Eunseo, Han, Seunghoon, Park, Sung-Soo, Choi, Suein, Joo, Sung Hwan, Park, Seok Jun, Shin, Beomjin, Kim, Donghyun, Kim, Hyeonsu, Jung, Yujung, Lee, Kyung-Tae, Chung, Eun Kyoung

“…This study aimed to develop a fully validated HPLC-MS/MS method for quantifying total and unbound lenalidomide concentrations in human plasma. Unbound…”
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Development and Validation of Simple LC-MS-MS Assay for the Quantitative Determination of Ticagrelor in Human Plasma: its Application to a Bioequivalence Study by Chae, Soo-In, Yoo, Hee Jo, Lee, Su-Yeon, Chung, Eun Kyoung, Shim, Wang-Seob, Lee, Kyung-Tae

“…Abstract A sensitive, rapid, reproducible and reliable high-performance liquid chromatography-electrospray ionization tandem mass spectrometric method has been…”
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Pharmacokinetic Comparison of Ginsenosides between Fermented and Non-Fermented Red Ginseng in Healthy Volunteers by Shin, Myeong-Bae, Kim, Sung-Ah, Lee, Sooyoung, Shim, Wang-Seob, Lee, Kyung-Tae, Lee, Seung-Kwon, Yim, Sung-Vin, Kim, Bo-Hyung

“…Fermentation of red ginseng (RG) produces fermented red ginseng (FRG), thereby increasing the relative amount of downstream ginsenosides, including compound Y…”
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Bioequivalence assessment of Fumatifen® tablet to Zaditen® tablet (ketotifen fumarate 1 mg) by liquid chromatography tandem mass spectrometry by Nam, Kyung-Don, Tak, Sung-Kwon, Park, Ji-Sun, Cho, Min-Ho, Yim, Sung-Vin, Shim, Wang-Seob, Cho, Hyun-Suk, Park, Mi-Sun, Lee, Kyung-Tae

“…A sensitive and specific liquid chromatographic method coupled with tandem mass spectrometry was developed and validated for the analysis of ketotifen. After…”
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Development of simple and rapid LC–MS/MS method for determination of celecoxib in human plasma and its application to bioequivalence study by Park, Mi-Sun, Shim, Wang-Seob, Yim, Sung-Vin, Lee, Kyung-Tae

“…► Simple and rapid method to determine celecoxib in human plasma with a total running time of 2min for each sample. ► Validated for specificity, LLOQ,…”
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A Pharmacokinetic Drug Interaction Between Fimasartan and Linagliptin in Healthy Volunteers by Kang, Woo Youl, Lee, Hae Won, Gwon, Mi-Ri, Cho, Seungil, Shim, Wang-Seob, Lee, Kyung-Tae, Yang, Dong Heon, Seong, Sook Jin, Yoon, Young-Ran

“…Fimasartan, an angiotensin II type 1 receptor blocker, and linagliptin, a dipeptidyl-peptidase-4 inhibitor, are frequently coadministered to treat patients…”
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Development and validation of an LC-MS/MS method for the determination of pelubiprofen and its active metabolite, trans-alcohol, in human plasma and its application to pharmacokinetic study by Ryu, Ju-Hee, Park, Ji-Sun, Jo, Min-ho, Kim, Joo-Il, Shim, Wang-Seob, Kim, Bo-Hyung, Yim, Sung-Vin, Hong, Jongki, Lee, Kyung-Tae

“…•We have developed LC-MS/MS method to analyze pelubiprofen and its active metabolite (trans-OH) in human plasma.•This method is selective, reproducible, and…”
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Development of liquid chromatography tandem mass spectrometry method for determination of spironolactone in human plasma: application to a bioequivalence study of Daewon Spiracton tablet® (spironolactone 50 mg) by Lee, Jeong-Hun, An, Tae-Gil, Kim, Su Jung, Shim, Wang-Seob, Lee, Kyung-Tae

“…A sensitive LC–MS/MS method was developed and fully validated for the determination of spironolactone in human plasma using spironolactone-d 6 as an internal…”
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