Search Results - "Shim, Hyun Joo"

Suaeda glauca Attenuates Liver Fibrosis in Mice by Inhibiting TGFβ1-Smad2/3 Signaling in Hepatic Stellate Cells by Hong, You-Jung, Kim, Gil-Hwan, Park, Yongdo, Jo, Hye-Jin, Nam, Min-Woo, Kim, Dong-Gu, Cho, Hwangeui, Shim, Hyun-Joo, Jin, Jong-Sik, Rho, Hyunsoo, Han, Chang-Yeob

“…Chronic liver injury due to various hepatotoxic stimuli commonly leads to fibrosis, which is a crucial factor contributing to liver disease-related mortality…”
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Involvement of progranulin in the enhancement of hippocampal neurogenesis by voluntary exercise by Asakura, Rei, Matsuwaki, Takashi, Shim, Joo-Hyun, Yamanouchi, Keitaro, Nishihara, Masugi

“…We have previously suggested that progranulin mediates the stimulatory effects of estrogen on adult neurogenesis in the hippocampus. Neurogenesis in mature…”
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Comparative metabolism of aschantin in human and animal hepatocytes by Lee, Min Seo, Shim, Hyun Joo, Cho, Yong-Yeon, Lee, Joo Young, Kang, Han Chang, Song, Im-Sook, Lee, Hye Suk

“…Aschantin, a tetrahydrofurofuran lignan with a 1,3-benzodioxole group derived from Flos Magnoliae , exhibits antioxidant, anti-inflammatory, cytotoxic, and…”
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Osmolarity at early culture stage affects development and expression of apoptosis related genes (bax-α and bcl-xl) in pre-implantation porcine NT embryos by Hwang, In-Sun, Park, Mi-Rung, Moon, Hyo-Jin, Shim, Joo-Hyun, Kim, Dong-Hoon, Yang, Byoung-Chul, Ko, Yeoung-Gyu, Yang, Boh-Suk, Cheong, Hee-Tae, Im, Gi-Sun

“…This study examined whether high osmolarity of culture medium at the early culture stage affects development and expression of apoptosis related genes (Bax‐α…”
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Application of a Dowex-50WX8 chromatographic process to the preparative-scale separation of galactose, levulinic acid, and 5-hydroxymethylfurfural in acid hydrolysate of agarose by Valentin, Elizabeth, Nam, Hee-Geun, Kim, Pung-Ho, Joo, Hyun Woo, Shim, Hyun Joo, Chang, Yong Keun, Mun, Sungyong

“…•Three useful compounds from agarose hydrolysis were separated by chromatography.•The adsorbent used in the proposed chromatographic process was…”
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Profiling Cannabinoid Contents and Expression Levels of Corresponding Biosynthetic Genes in Commercial Cannabis ( Cannabis sativa L.) Cultivars by Kim, Ae Lim, Yun, Young Jae, Choi, Hyong Woo, Hong, Chang-Hee, Shim, Hyun Joo, Lee, Jeong Hwan, Kim, Young-Cheon

“…( L.) is widely cultivated and studied for its psychoactive and medicinal properties. As the major cannabinoids are present in acidic forms in plants,…”
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Transport of a new erectogenic udenafil in Caco-2 cells by Ji, Hye Young, Shim, Hyun Joo, Yoo, Moohi, Park, Eun-Seok, Lee, Hye Suk

“…P-glycoprotein, an ATP-dependent efflux pump, is a membrane transporter that influences the absorption and excretion of drugs. There is a striking overlap…”
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Modeling of ammonium lactate recovery and impurity removal from simulated fermentation broth by nanofiltration by Kim, Jae Hyung, Na, Jeong-Geol, Shim, Hyun Joo, Chang, Yong Keun

“…► A mechanistic nanofiltration (NF) model has been developed. ► It is for the simulation of NF process for lactate recovery from fermentation broth. ► It can…”
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Forward Bending in Supine Test: Diagnostic Accuracy for Acute Vertebral Fragility Fracture by Jung, Chan-Woo, Lee, Jeongik, Ham, Dae-Woong, Kang, Hyun, Chang, Dong-Gune, Kim, Youngbae B, Ahn, Young-Joon, Shim, Joo Hyun, Song, Kwang-Sup

“…Despite its high incidence rate, vertebral fragility fracture (VFF) is frequently underdiagnosed due to the absence of marked symptoms. This study evaluated…”
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In Vitro Metabolic Pathways of the New Anti-Diabetic Drug Evogliptin in Human Liver Preparations by Jeong, Hyeon-Uk, Kim, Ju-Hyun, Lee, Dae Young, Shim, Hyun Joo, Lee, Hye Suk

“…Evogliptin ((R)-4-((R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-3-(tert-butoxymethyl)-piperazin-2-one), is a new dipeptidyl peptidase IV inhibitor used for…”
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Corydaline inhibits multiple cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in human liver microsomes by Ji, Hye Young, Liu, Kwang Hyeon, Lee, Hyeri, Im, Sae Rom, Shim, Hyun Joo, Son, Miwon, Lee, Hye Suk

“…Corydaline is a bioactive alkaloid with various antiacetylcholinesterase, antiallergic, and antinociceptive activities found in the medicinal herb Corydalis…”
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Bioanalytical validation for the determination of evogliptin and its metabolites m7/m8 in human plasma by liquid chromatography-tandem mass spectrometry by Cho, Kyunghee, Joung, Sun Koung, La, Sookie, Lee, Dae Young, Shim, Hyun Joo, Song, Ji Su, Lee, Hee Joo

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Transport of a New Erectogenic Udenafil in Caco-2 Cells by Ji, Hye-Young, Shim, Hyun-Joo, Yoo, Moo-Hi, Park, Eun-Seok, Lee, Hye-Suk

“…P-glycoprotein, an ATP-dependent efflux pump, is a membrane transporter that influences the absorption and excretion of drugs. There is a striking overlap…”
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In vitro metabolism of corydaline in human liver microsomes and hepatocytes using liquid chromatography-ion trap mass spectrometry by Ji, Hye Young, Lee, Hyeri, Kim, Jeong-Han, Kim, Ki Hyun, Lee, Kang Ro, Shim, Hyun Joo, Son, Miwon, Lee, Hye Suk

“…Corydaline is a pharmacologically active isoquinoline alkaloid isolated from Corydalis tubers. It exhibits the antiacetylcholinesterase, antiallergic,…”
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Candidate Molecule for Premature Ejaculation, DA-8031: In Vivo and In Vitro Characterization of DA-8031 by Jeon, Hyung-Jun, Kim, Hae-Sun, Lee, Chan-Ho, Lee, Young-Gun, Choi, Seol-Min, Sohn, Yong-Sung, Shin, Chang-Yong, Kim, Junghoon, Shim, Hyun-Joo, Kang, Kyung-Koo, Ahn, Byoung-Ok, Kim, Soon-Hoe

“…Objectives To evaluate the efficacy of DA-8031 against premature ejaculation, we performed in vitro and in vivo pharmacologic studies. Methods We used a…”
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Ship part nesting by pattern recognition and group arrangement by Lee, Cheol-Soo, Heo, Eun-Young, Shim, Joo-Hyun, Chen, F. Frank, Kim, Dong-Won

“…The automatic nesting for a computer-aided manufacturing (CAM) system in shipbuilding industry requires more constraints than in other fields such as…”
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Squamous Cell Carcinoma and Multiple Bowen's Disease in a Patient with a History of Consumption of Traditional Chinese Herbal Balls by Seok, Joon, Park, Kui Young, Li, Kapsok, Kim, Beom Joon, Shim, Joo Hyun, Seo, Seong Jun, Kim, Myeung Nam, Hong, Chang Kwun

“…Arsenic has been classified as a class I human carcinogen, meaning that there is sufficient evidence of carcinogenicity to humans. Arsenic, however, remains a…”
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Effect of DA-8159, a Selective Phosphodiesterase Type 5 Inhibitor, on Electroretinogram and Retinal Histology in Rabbits by 조호균, Kang Kyung Koo, Ahn Gook Jun, Shim Hyun Joo, Kim Won Bae

“…DA-8159, a selective inhibitor of phosphodiesterase type 5, was developed as a new drug for erectile dysfunction. The effect of DA-8159 on the…”
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Quantification of a novel PPARγ partial agonist (S)-2-ethoxy-3-(4-{3-methyl-5-[4-(3-methyl-isoxazol-5-yl)-phenyl]thiophen-2-ylmethoxy}-phenyl)-propionic acid (PAM-1616) in rat plasma using liquid chromatography-tandem mass spectrometry by Chae, Hye Won, Jung, Haehum, Kim, Eun Jung, Shim, Hyun Joo, Lim, Joong In, Ji, Hye Young, Lee, Hye Suk

“…( S )-2-ethoxy-3-(4-{3-methyl-5-[4-(3-methyl-isoxazol-5-yl)-phenyl]thiophen-2-ylmethoxy}-phenyl)-propionic acid (PAM-1616) is a novel peroxisome…”
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Liquid chromatography-tandem mass spectrometry of a new PPARα/γ dual agonist PAR-5359 in rat plasma by Kim, Dong Kyun, Park, Eun Jeong, Jeong, Ji Hyun, Jeon, Sun Ho, Kim, Eun Jung, Shim, Hyun Joo, Lim, Joong In, Lee, Hye Suk

“…PAR-5359, 3-(4-{2-[4-(4-Chloro-phenyl)-3,6-dihydro-2H-pyridin-1-yl]-ethoxy}-phenyl)-2-ethoxypropionic acid, is a well-balanced PPARα/γ dual agonist with the…”
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