Search Results - "Shilovskiy, Igor"

Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer by Dmitrieva-Posocco, Oxana, Dzutsev, Amiran, Posocco, David F., Hou, Vivianty, Yuan, Wuxing, Thovarai, Vishal, Mufazalov, Ilgiz A., Gunzer, Matthias, Shilovskiy, Igor P., Khaitov, Musa R., Trinchieri, Giorgio, Waisman, Ari, Grivennikov, Sergei I.

“…Chronic inflammation drives the progression of colorectal cancer (CRC). Increased expression of interleukin (IL)-17A is associated with poor prognosis, and…”
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Past, present, and future of allergen immunotherapy vaccines by Dorofeeva, Yulia, Shilovskiy, Igor, Tulaeva, Inna, Focke‐Tejkl, Margarete, Flicker, Sabine, Kudlay, Dmitriy, Khaitov, Musa, Karsonova, Antonina, Riabova, Ksenja, Karaulov, Alexander, Khanferyan, Roman, Pickl, Winfried F., Wekerle, Thomas, Valenta, Rudolf

“…Allergen‐specific immunotherapy (AIT) is an allergen‐specific form of treatment for patients suffering from immunoglobulin E (IgE)‐associated allergy; the most…”
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Antiviral Therapy of COVID-19 by Gudima, Georgii, Kofiadi, Ilya, Shilovskiy, Igor, Kudlay, Dmitry, Khaitov, Musa

“…Since the beginning of the COVID-19 pandemic, the scientific community has focused on prophylactic vaccine development. In parallel, the experience of the…”
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Cell-Penetrating Peptides as Vehicles for Delivery of Therapeutic Nucleic Acids. Mechanisms and Application in Medicine by Timotievich, Ekaterina D., Shilovskiy, Igor P., Khaitov, Musa R.

“…Currently, nucleic acid therapeutics are actively developed for the treatment and prophylactic of metabolic disorders and oncological, inflammatory, and…”
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Role of STAT3 Transcription Factor in Pathogenesis of Bronchial Asthma by Nikolskii, Aleksandr A., Shilovskiy, Igor P., Barvinskaia, Ekaterina D., Korneev, Artem V., Sundukova, Maria S., Khaitov, Musa R.

“…Bronchial asthma is a heterogeneous chronic inflammatory disease of airways. The studies of molecular and cellular mechanisms of bronchial asthma have…”
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Role and Molecular Mechanisms of Alternative Splicing of Th2-Cytokines IL-4 and IL-5 in Atopic Bronchial Asthma by Shilovskiy, Igor P., Kovchina, Valeriya I., Timotievich, Ekaterina D., Nikolskii, Alexander A., Khaitov, Musa R.

“…Bronchial asthma (BA) is a heterogeneous chronic inflammatory disease of the respiratory tract. Allergic (atopic) asthma is the most common (up to 80% of…”
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Murine model of steroid-resistant neutrophilic bronchial asthma as an attempt to simulate human pathology by Shilovskiy Igor, P., Nikolskii Aleksandr, A., Kovchina Valeriya, I., Vishniakova Lyudmila, I., Yumashev Kirill, V., Barvinskaia Ekaterina, D., Kaganova Mariya, M., Korneev Artem, V., Turenko Vladislav, N., Brylina Vera, E., Petukhova Olga, A., Kudlay Dmitry, A., Khaitov Musa, R.

“…Bronchial asthma (BA) is a heterogeneous chronic inflammatory disease of the airways. The majority of patients with mild to moderate BA develop Th2-biased…”
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Molecular and Cellular Mechanisms of Respiratory Syncytial Viral Infection: Using Murine Models to Understand Human Pathology by Shilovskiy, Igor P., Yumashev, Kirill V., Nikolsky, Alexandr A., Vishnyakova, Liudmila I., Khaitov, Musa R.

“…Respiratory syncytial virus (RSV) causes severe pathology of the lower respiratory tract in infants, immunocompromised people, and elderly. Despite decades of…”
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Clearing of Foreign Episomal DNA from Human Cells by CRISPRa-Mediated Activation of Cytidine Deaminases by Brezgin, Sergey, Kostyusheva, Anastasiya, Ponomareva, Natalia, Volia, Viktoriia, Goptar, Irina, Nikiforova, Anastasiya, Shilovskiy, Igor, Smirnov, Valery, Kostyushev, Dmitry, Chulanov, Vladimir

“…Restriction of foreign DNA is a fundamental defense mechanism required for maintaining genomic stability and proper function of mammalian cells. APOBEC…”
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From Allergen Molecules to Molecular Immunotherapy of Nut Allergy: A Hard Nut to Crack by Fuhrmann, Verena, Huang, Huey-Jy, Akarsu, Aysegul, Shilovskiy, Igor, Elisyutina, Olga, Khaitov, Musa, van Hage, Marianne, Linhart, Birgit, Focke-Tejkl, Margarete, Valenta, Rudolf, Sekerel, Bulent Enis

“…Peanuts and tree nuts are two of the most common elicitors of immunoglobulin E (IgE)-mediated food allergy. Nut allergy is frequently associated with systemic…”
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A novel peptide dendrimer LTP efficiently facilitates transfection of mammalian cells by Kozhikhova, Ksenia V, Andreev, Sergey M, Shilovskiy, Igor P, Timofeeva, Anastasiia V, Gaisina, Alina R, Shatilov, Artem A, Turetskiy, Evgeny A, Andreev, Igor M, Smirnov, Valeriy V, Dvornikov, Anton S, Khaitov, Musa R

“…One of the urgent problems of gene therapy is the search for effective transfection methods. Synthetic cationic peptides (CPs) are considered to be one of the…”
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Genotoxicity of cationic lipopeptide nanoparticles by Zhanataev, Aliy K., Anisina, Elena A., Kulakova, Alla V., Shilovskiy, Igor P., Lisitsyn, Artem A., Koloskova, Olesya O., Khaitov, Musa R., Durnev, Andrey D.

“…•Cationic lipopeptide nanoparticles caused DNA damage in liver, lung and kidney of mice.•Genotoxicity was confirmed in vitro on human blood cells.•No increase…”
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Small interfering RNAs targeted to interleukin-4 and respiratory syncytial virus reduce airway inflammation in a mouse model of virus-induced asthma exacerbation by Khaitov, Musa R, Shilovskiy, Igor P, Nikonova, Aleksandra A, Shershakova, Nadezda N, Kamyshnikov, Oleg Y, Babakhin, Alexander A, Zverev, Vitaly V, Johnston, Sebastian L, Khaitov, Rakhim M

“…Asthma exacerbations are caused primarily by viral infections. Antisense and small interfering RNA (siRNA) technologies have gained attention as potential…”
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Protective Allele for Multiple Sclerosis HLA-DRB101:01 Provides Kinetic Discrimination of Myelin and Exogenous Antigenic Peptides by Mamedov, Azad, Vorobyeva, Nadezhda, Filimonova, Ioanna, Zakharova, Maria, Kiselev, Ivan, Bashinskaya, Vitalina, Baulina, Natalia, Boyko, Alexey, Favorov, Alexander, Kulakova, Olga, Ziganshin, Rustam, Smirnov, Ivan, Poroshina, Alina, Shilovskiy, Igor, Khaitov, Musa, Sykulev, Yuri, Favorova, Olga, Vlassov, Valentin, Gabibov, Alexander, Belogurov, Jr, Alexey

“…Risk of the development of multiple sclerosis (MS) is known to be increased in individuals bearing distinct class II human leukocyte antigen (HLA) variants,…”
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Linear and dendrimeric antiviral peptides: design, chemical synthesis and activity against human respiratory syncytial virus by Kozhikhova, Ksenia V, Shilovskiy, Igor P, Shatilov, Artem A, Timofeeva, Anastasiia V, Turetskiy, Evgeny A, Vishniakova, Liudmila I, Nikolskii, Aleksandr A, Barvinskaya, Ekaterina D, Karthikeyan, Subramani, Smirnov, Valeriy V, Kudlay, Dmitriy A, Andreev, Sergey M, Khaitov, Musa R

“…Respiratory syncytial virus (RSV) is one of the most common viral pathogens. It is especially dangerous for newborns and young children. In some cases it could…”
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Identification of a novel splice variant for mouse and human interleukin-5 by Shilovskiy, Igor, Andreev, Sergei, Mazurov, Dmitriy, Barvinskaia, Ekaterina, Bolotova, Svetlana, Nikolskii, Alexander, Sergeev, Ilya, Maerle, Artem, Kudlay, Dmitrii, Khaitov, Musa

“…Expression of interleukins and their receptors is often regulated by alternative splicing. Alternative isoform of IL-5 receptor α-chain is well studied;…”
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Silencing of SARS‐CoV‐2 with modified siRNA‐peptide dendrimer formulation by Khaitov, Musa, Nikonova, Alexandra, Shilovskiy, Igor, Kozhikhova, Ksenia, Kofiadi, Ilya, Vishnyakova, Lyudmila, Nikolskii, Alexander, Gattinger, Pia, Kovchina, Valeria, Barvinskaia, Ekaterina, Yumashev, Kirill, Smirnov, Valeriy, Maerle, Artem, Kozlov, Ivan, Shatilov, Artem, Timofeeva, Anastasiia, Andreev, Sergey, Koloskova, Olesya, Kuznetsova, Nadezhda, Vasina, Daria, Nikiforova, Maria, Rybalkin, Sergei, Sergeev, Ilya, Trofimov, Dmitriy, Martynov, Alexander, Berzin, Igor, Gushchin, Vladimir, Kovalchuk, Aleksey, Borisevich, Sergei, Valenta, Rudolf, Khaitov, Rakhim, Skvortsova, Veronica

“…Background First vaccines for prevention of Coronavirus disease 2019 (COVID‐19) are becoming available but there is a huge and unmet need for specific forms of…”
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IgE‐reactivity profiles to allergen molecules in Russian children with and without symptoms of allergy revealed by micro‐array analysis by Elisyutina, Olga, Lupinek, Christian, Fedenko, Elena, Litovkina, Alla, Smolnikov, Evgenii, Ilina, Nataliya, Kudlay, Dmitry, Shilovskiy, Igor, Valenta, Rudolf, Khaitov, Musa, Santos, Alexandra

“…Background The analysis of longitudinal birth cohorts with micro‐arrayed allergen molecules has provided interesting information about the evolution of IgE…”
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Natural human Bet v 1‐specific IgG antibodies recognize non‐conformational epitopes whereas IgE reacts with conformational epitopes by Brazhnikov, Georgii, Smolnikov, Evgenii, Litovkina, Alla, Jiang, Tianchi, Shatilov, Artem, Tulaeva, Inna, Tulaev, Mikhail, Karaulov, Alexander, Poroshina, Alina, Zhernov, Yury, Focke‐Tejkl, Margarete, Weber, Milena, Akinfenwa, Oluwatoyin, Elisyutina, Olga, Andreev, Sergey, Shilovskiy, Igor, Shershakova, Nadezhda, Smirnov, Valeriy, Fedenko, Elena, Lepeshkova, Tatiana Sergeevna, Beltyukov, Evgeny Cronidovich, Naumova, Veronika Victorovna, Kundi, Michael, Khaitov, Musa, Wiedermann, Ursula, Valenta, Rudolf, Campana, Raffaela

“…Background The nature of epitopes on Bet v 1 recognized by natural IgG antibodies of birch pollen allergic patients and birch pollen‐exposed but non‐sensitized…”
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Anti‐inflammatory effect of siRNAs targeted il‐4 and il‐13 in a mouse model of allergic rhinitis by Shilovskiy, Igor, Nikonova, Alexandra, Barvinskaia, Ekaterina, Kaganova, Mariya, Nikolskii, Aleksandr, Vishnyakova, Lyudmila, Kovchina, Valeriia, Yumashev, Kirill, Korneev, Artem, Petukhova, Olga, Kudlay, Dmitry, Smirnov, Valeriy, Andreev, Sergey, Kozhikhova, Ksenia, Shatilov, Artem, Shatilova, Anastasiia, Maerle, Artem, Sergeev, Ilya, Trofimov, Dmitry, Khaitov, Musa

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