Search Results - "Shillitoe, E J"

Effect of a caspase inhibitor, zVADfmk, on the inhibition of breast cancer cells by herpes simplex virus type 1 by Wood, L W, Shillitoe, E J

“…The oncolytic effects of herpes simplex virus-1 (HSV-1) are limited, possibly because of premature death of infected cells by apoptosis, which limits the…”
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Papillomaviruses as targets for cancer gene therapy by Shillitoe, E J

“…The human papillomaviruses (HPVs) are a diverse group of infectious agents, some of which are a causative agent of human cancers. Cervical cancer and oral…”
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Gene discovery in oral squamous cell carcinoma through the Head and Neck Cancer Genome Anatomy Project: confirmation by microarray analysis by Leethanakul, C, Knezevic, V, Patel, V, Amornphimoltham, P, Gillespie, J, Shillitoe, E.J, Emko, P, Park, M.H, Emmert-Buck, M.R, Strausberg, R.L, Krizman, D.B, Gutkind, J.S

“…The near completion of the human genome project and the recent development of novel, highly sensitive high-throughput techniques have now afforded the unique…”
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The high risk human papillomaviruses and oral cancer: evidence for and against a causal relationship by Sugerman, PB, Shillitoe, EJ

“…Oncogenic human papillomaviruses (HPVs) have been detected in oral squamous cell carcinoma (SCC).HPV16 is the most frequently detected HPV type in oral SCC and…”
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Clinical and pathological features of the murine AT-84 orthotopic model of oral cancer by Lou, E, Kellman, RM, Hutchison, R, Shillitoe, EJ

“…Objective:  The murine AT‐84 orthotopic model of oral cancer was assessed to find how similar it is to human oral cancer. This was done because testing of new…”
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Effect of herpes simplex virus type-1 on growth of oral cancer in an immunocompetent, orthotopic mouse model by Lou, E, Kellman, R.M, Shillitoe, E.J

“…Herpes simplex virus type-1 has been proposed as an agent for the treatment of oral cancer. Experiments were designed to test its effectiveness in an animal…”
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Strength and specificity of different gene promoters in oral cancer cells by Shillitoe, E.J, Noonan, S

“…Gene therapy of oral cancer will require expression of genes by promoters that are both powerful and relatively tumor specific. We compared the level of…”
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Induction of Apoptosis in Oral Cancer Cells by an Anti-bcl-2 Ribozyme Delivered by an Adenovirus Vector by GIBSON, S. A, PELLENZ, C, HUTCHISON, R. E, DAVEY, F. R, SHILLITOE, E. J

“…Human oral cancer cells may have any of several genetic changes, but the role of the bcl -2 oncogene is relatively unexplored. To find out if this gene plays a…”
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Gene therapy for oral cancer: recent progress in research by Shillitoe, E.J

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Effects of herpes simplex virus on human oral cancer cells, and potential use of mutant viruses in therapy of oral cancer by Shillitoe, E.J, Gilchrist, E, Pellenz, C, Murrah, V

“…The herpes simplex virus type-1 (HSV-1) might be useful in treatment of oral cancer because it is strongly cytolytic, and its natural target tissue is the…”
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Genome-wide analysis of oral cancer—early results from the Cancer Genome Anatomy Project by Shillitoe, E.J., May, M., Patel, V., Lethanakul, C., Ensley, J.F., Strausberg, R.L., Gutkind, J.S.

“…The Cancer Genome Anatomy Project (CGAP) is a large cooperative effort sponsored by the US National Institutes of Health designed to find, catalog and annotate…”
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Mutations in the long control region of human papillomavirus DNA in oral cancer cells, and their functional consequences by CHEN, Z, STORTHZ, K. A, SHILLITOE, E. J

“…Oral cancers frequently contain DNA of human papillomavirus (HPV) type 16 or 18, but the functional significance of this is unclear. A role for HPV in the…”
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Development of an oncolytic herpes simplex virus using a tumor-specific HIF-responsive promoter by Longo, S L, Griffith, C, Glass, A, Shillitoe, E J, Post, D E

“…We exploited the differential activation of hypoxia-inducible factor (HIF)-dependent gene expression in tumors versus normal tissue for the design of a…”
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Evaluation of topical gene therapy for head and neck squamous cell carcinoma in an organotypic model by EICHER, S. A, CLAYMAN, G. L, LIU, T.-J, SHILLITOE, E. J, STORTHZ, K. A, ROTH, J. A, LOTAN, R

“…The organotypic (raft) culture system has been shown to be a useful model for examining the effects of biochemical manipulations on various epithelial cell…”
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Effects of human papillomavirus type 18-specific antisense oligonucleotides on the transformed phenotype of human carcinoma cell lines by STEELE, C, COWSERT, L. M, SHILLITOE, E. J

“…DNA of human papillomavirus type 18 is present in several human cancer cell lines that were derived from oral or cervical tumors, and it is known that several…”
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Oral cancer research in the new millennium by Shillitoe, E J, Scully, C

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An oncolytic mutant of herpes simplex virus type-1 in which replication is governed by a promoter enhancer of human papillomavirus type-16 by Griffith, C, Noonan, S, Lou, E, Shillitoe, E J

“…Although herpes simplex virus type-1 (HSV-1) can be used as an oncolytic virus it has the undesirable side effect of neurotoxicity. To create a virus with…”
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Effect of different antibiotics on efficiency of transformation of bacteria by electroporation by Steele, C, Zhang, S, Shillitoe, E J

“…We noted large differences in the transformation efficiency of Escherichia coli when different methods were used for transformation. To analyze these…”
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Natural killer cell activity and head and neck cancer: a clinical assessment by Schantz, S P, Shillitoe, E J, Brown, B, Campbell, B

“…In 127 patients with squamous cell carcinoma of the upper aerodigestive system, an assessment of natural killer (NK) cell function was performed. The mean…”
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A DNA sequence editor with voice input and output by Shillitoe, E J

“…DNA sequence editors for IBM PC-compatible computers are often line-oriented, with complicated methods of entering and modifying sequences. This paper…”
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