Search Results - "Shillingford, J M"

Signal Transducer and Activator of Transcription (Stat) 5 Controls the Proliferation and Differentiation of Mammary Alveolar Epithelium by Miyoshi, Keiko, Shillingford, Jonathan M., Smith, Gilbert H., Grimm, Sandra L., Wagner, Kay-Uwe, Oka, Takami, Rosen, Jeffrey M., Robinson, Gertraud W., Hennighausen, Lothar

“…Functional development of mammary epithelium during pregnancy depends on prolactin signaling. However, the underlying molecular and cellular events are not…”
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Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5 by Long, Weiwen, Wagner, Kay-Uwe, Lloyd, K C Kent, Binart, Nadine, Shillingford, Jonathan M, Hennighausen, Lothar, Jones, Frank E

“…The ERBB family of type 1 receptor tyrosine kinases and their ligands have crucial functions during mammopoiesis, but the signaling networks that ultimately…”
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Activation of β-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation by BIERIE, Brian, NOZAWA, Masahiro, ROBINSON, Gertraud W, HENNIGHAUSEN, Lothar, RENOU, Jean-Pierre, SHILLINGFORD, Jonathan M, MORGAN, Fanta, OKA, Takami, TAKETO, Makoto M, CARDIFF, Robert D, MIYOSHI, Keiko, WAGNER, Kay-Uwe

“…The Wnt/beta-catenin signaling pathway is critical for normal mammalian development, the specification of epidermal cells and neoplastic transformation of…”
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Activation of β-Catenin Signaling in Differentiated Mammary Secretory Cells Induces Transdifferentiation into Epidermis and Squamous Metaplasias by Miyoshi, Keiko, Shillingford, Jonathan M., Le Provost, Fabienne, Gounari, Fotini, Bronson, Roderick, von Boehmer, Harald, Taketo, Makoto M., Cardiff, Robert D., Hennighausen, Lothar, Khazaie, Khashayarsha

“…Mammary anlagen are formed in the embryo as a derivative of the epidermis, a process that is controlled by Lef-1 and therefore possibly by β-catenin. To…”
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Development of the mammary gland requires DGAT1 expression in stromal and epithelial tissues by Cases, Sylvaine, Zhou, Ping, Shillingford, Jonathan M, Wiseman, Bryony S, Fish, Jo Dee, Angle, Christina S, Hennighausen, Lothar, Werb, Zena, Farese, Jr, Robert V

“…Mammary gland development is a complex process that is dependent on interactions between the developing mammary epithelium and the surrounding stromal tissues…”
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Experimental mouse genetics – answering fundamental questions about mammary gland biology by Shillingford, Jonathan M, Hennighausen, Lothar

“…Contemporary gene-targeting techniques now make it possible to alter specific genes in the genome. As a result, a plethora of mouse models have been generated…”
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Mechanisms of phosphate transport in the lactating rat mammary gland by Shillingford, J M, Shennan, D B, Beechey, R B

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The regulation of anion transport in lactating rat mammary tissue by Shillingford, J M, Shennan, D B, Beechey, R B

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Phosphate transport via Na+ -Pi cotransport and anion exchange in lactating rat mammary tissue by Shillingford, J M, Calvert, D T, Beechey, R B, Shennan, D B

“…Inorganic orthophosphate (Pi) transport, using 32P-labelled orthophosphate as tracer, by lactating rat mammary tissue has been examined using both tissue…”
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Determination of the sequence of a mRNA from lactating sheep mammary gland that encodes a protein identical to the Na(+)-dependent glucose transporter (SGLT1) by Shillingford, J M, Wood, I S, Shennan, D B, Shirazi-Beechey, S P, Beechey, R B

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The inhibition of Na(+)-Pi cotransport and Pi self-exchange mechanisms in lactating rat mammary tissue by Shillingford, J M, Beechey, R B, Shennan, D B

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Conditional deletion of the bcl-x gene from mouse mammary epithelium results in accelerated apoptosis during involution but does not compromise cell function during lactation by Walton, K D, Wagner, K U, Rucker, 3rd, E B, Shillingford, J M, Miyoshi, K, Hennighausen, L

“…In the mammary gland Bcl-x is the most abundant cell survival factor from the Bcl-2 family. Since Bcl-x null mice die around day 12 of embryogenesis, the…”
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The mTOR Pathway Is Regulated by Polycystin-1, and Its Inhibition Reverses Renal Cystogenesis in Polycystic Kidney Disease by Shillingford, Jonathan M., Murcia, Noel S., Larson, Claire H., Low, Seng Hui, Hedgepeth, Ryan, Brown, Nicole, Flask, Chris A., Novick, Andrew C., Goldfarb, David A., Kramer-Zucker, Albrecht, Walz, Gerd, Piontek, Klaus B., Germino, Gregory G., Weimbs, Thomas

“…Autosomal-dominant polycystic kidney disease (ADPKD) is a common genetic disorder that frequently leads to renal failure. Mutations in polycystin-1 (PC1)…”
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Partnering With Stakeholders to Inform the Co-Design of a Psychosocial Intervention for Prenatally Diagnosed Congenital Heart Disease by Sood, Erica, Gramszlo, Colette, Perez Ramirez, Alejandra, Braley, Katherine, Butler, Samantha C, Davis, Jo Ann, Divanovic, Allison A, Edwards, Lindsay A, Kasparian, Nadine, Kelly, Sarah L, Neely, Trent, Ortinau, Cynthia M, Riegel, Erin, Shillingford, Amanda J, Kazak, Anne E

“…Input from diverse stakeholders is critical to the process of designing healthcare interventions. This study applied a novel mixed-methods, stakeholder-engaged…”
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50 Years Ago in T he J ournal of P ediatrics by Shillingford, Amanda J., MD, Gidding, Samuel S., MD

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Growth Asymmetry, Head Circumference, and Neurodevelopmental Outcomes in Infants with Single Ventricles by Miller, Thomas A., DO, Zak, Victor, PhD, Shrader, Peter, MA, Ravishankar, Chitra, MD, Pemberton, Victoria L., RNC, MS, Newburger, Jane W., MD, Shillingford, Amanda J., MD, Dagincourt, Nicholas, MS, Cnota, James F., MD, Lambert, Linda M., MSN, Sananes, Renee, PhD, Richmond, Marc E., MD, MS, Hsu, Daphne T., MD, Miller, Stephen G., MD, Zyblewski, Sinai C., MD, Williams, Richard V., MD

“…Objective To assess the variability in asymmetric growth and its association with neurodevelopment in infants with single ventricle (SV). Study design We…”
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Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium by Shillingford, Jonathan M, Miyoshi, Keiko, Robinson, Gertraud W, Grimm, Sandra L, Rosen, Jeffrey M, Neubauer, Hans, Pfeffer, Klaus, Hennighausen, Lothar

“…The PRL receptor (PrlR) and the signal transducer and activator of transcription 5a (Stat5a) are essential for the proliferation and differentiation of mammary…”
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Proteotyping of Mammary Tissue from Transgenic and Gene Knockout Mice with Immunohistochemical Markers: a Tool To Define Developmental Lesions by Shillingford, Jonathan M, Miyoshi, Keiko, Robinson, Gertraud W, Bierie, Brian, Cao, Yixue, Karin, Michael, Hennighausen, Lothar

“…Through the use of transgenic and gene knockout mice, several studies have identified specific genes required for the functional development of mammary…”
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The Effect of the Superior Cavopulmonary Anastomosis on Ventricular Remodeling in Infants with Single Ventricle by Margossian, Renee, MD, Zak, Victor, PhD, Shillingford, Amanda J., MD, Hlavacek, Anthony M., MD, Cnota, James F., MD, Puchalski, Michael D., MD, Levine, Jami C., MD, McCrindle, Brian W., MD MPH, Cohen, Meryl S., MD, Altmann, Karen, MD, Barker, Piers C., MD, Hsu, Daphne T., MD, Colan, Steven D., MD

“…Background Infants with single ventricular physiology have volume and pressure overload that adversely affect ventricular mechanics. The impact of superior…”
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