Search Results - "Shill, Holly A."

Cueing Paradigms to Improve Gait and Posture in Parkinson's Disease: A Narrative Review by Muthukrishnan, Niveditha, Abbas, James J, Shill, Holly A, Krishnamurthi, Narayanan

“…Progressive gait dysfunction is one of the primary motor symptoms in people with Parkinson's disease (PD). It is generally expressed as reduced step length and…”
Get full text

REM sleep behavior disorder and neuropathology in Parkinson's disease by Postuma, Ronald B., Adler, Charles H., Dugger, Brittany N., Hentz, Joseph G., Shill, Holly A., Driver-Dunckley, Erika, Sabbagh, Marwan N., Jacobson, Sandra A., Belden, Christine M., Sue, Lucia I., Serrano, Geidy, Beach, Thomas G.

“…Introduction Rapid eye movement (REM) sleep behavior disorder (RBD) in Parkinson's disease (PD) is associated with differences in clinical phenotype, including…”
Get full text

Alpha-Synuclein Pathology and Axonal Degeneration of the Peripheral Motor Nerves Innervating Pharyngeal Muscles in Parkinson Disease by Mu, Liancai, Sobotka, Stanislaw, Chen, Jingming, Su, Hungxi, Sanders, Ira, Adler, Charles H, Shill, Holly A, Caviness, John N, Samanta, Johan E, Beach, Thomas G

“…ABSTRACTParkinson disease (PD) is a neurodegenerative disease primarily characterized by cardinal motor manifestations and CNS pathology. Current drug…”
Get full text

Concomitant pathologies among a spectrum of parkinsonian disorders by Dugger, Brittany N, Adler, Charles H, Shill, Holly A, Caviness, John, Jacobson, Sandra, Driver-Dunckley, Erika, Beach, Thomas G

“…Abstract Introduction Many clinicopathological studies do not specify the presence of other pathologies located within the brain, so disease heterogeneity may…”
Get full text

Unified Staging System for Lewy Body Disorders: Clinicopathologic Correlations and Comparison to Braak Staging by Adler, Charles H, Beach, Thomas G, Zhang, Nan, Shill, Holly A, Driver-Dunckley, Erika, Caviness, John N, Mehta, Shyamal H, Sabbagh, Marwan N, Serrano, Geidy E, Sue, Lucia I, Belden, Christine M, Powell, Jessica, Jacobson, Sandra A, Zamrini, Edward, Shprecher, David, Davis, Kathryn J, Dugger, Brittany N, Hentz, Joseph G

“…Abstract This study was designed to correlate clinical findings with the extent of pathologic a-synuclein (aSyn) in the brain using the Unified Staging System…”
Get full text

Effect of olfactory bulb pathology on olfactory function in normal aging by Tremblay, Cécilia, Serrano, Geidy E., Intorcia, Anthony J., Sue, Lucia I., Wilson, Jeffrey R., Adler, Charles H., Shill, Holly A., Driver‐Dunckley, Erika, Mehta, Shyamal H., Beach, Thomas G.

“…Decline of olfactory function is frequently observed in aging and is an early symptom of neurodegenerative diseases. As the olfactory bulb (OB) is one of the…”
Get full text

Simplified conversion method for unified Parkinson's disease rating scale motor examinations by Hentz, Joseph G., Mehta, Shyamal H., Shill, Holly A., Driver-Dunckley, Erika, Beach, Thomas G., Adler, Charles H.

“…ABSTRACT Background We evaluated a simplified method for converting Unified Parkinson's Disease Rating Scale Part III Motor Examination total scores (UPDRS…”
Get full text

Parkinson Disease Affects Peripheral Sensory Nerves in the Pharynx by Mu, Liancai, Sobotka, Stanislaw, Chen, Jingming, Su, Hungxi, Sanders, Ira, Nyirenda, Themba, Adler, Charles H, Shill, Holly A, Caviness, John N, Samanta, Johan E, Sue, Lucia I, Beach, Thomas G

“…ABSTRACTDysphagia is very common in patients with Parkinson disease (PD) and often leads to aspiration pneumonia, the most common cause of death in PD. Current…”
Get full text

Defining mild cognitive impairment in Parkinson's disease by Caviness, John N., Driver-Dunckley, Erika, Connor, Donald J., Sabbagh, Marwan N., Hentz, Joseph G., Noble, Brie, Evidente, Virgilio Gerald H., Shill, Holly A., Adler, Charles H.

“…Our purpose was to characterize a state of mild cognitive impairment (MCI) in Parkinson's disease (PD) (PD‐MCI) that would be analogous to the MCI that is…”
Get full text

RNA sequencing of olfactory bulb in Parkinson's disease reveals gene alterations associated with olfactory dysfunction by Tremblay, Cécilia, Aslam, Sidra, Walker, Jessica E., Lorenzini, Ileana, Intorcia, Anthony J., Arce, Richard A., Choudhury, Parichita, Adler, Charles H., Shill, Holly A., Driver-Dunckley, Erika, Mehta, Shyamal, Piras, Ignazio S., Belden, Christine M., Atri, Alireza, Beach, Thomas G., Serrano, Geidy E.

“…The olfactory bulb is involved early in the pathophysiology of Parkinson's disease (PD), which is consistent with the early onset of olfactory dysfunction…”
Get full text

Disease progression modelling reveals heterogeneity in trajectories of Lewy-type α-synuclein pathology by Mastenbroek, Sophie E., Vogel, Jacob W., Collij, Lyduine E., Serrano, Geidy E., Tremblay, Cécilia, Young, Alexandra L., Arce, Richard A., Shill, Holly A., Driver-Dunckley, Erika D., Mehta, Shyamal H., Belden, Christine M., Atri, Alireza, Choudhury, Parichita, Barkhof, Frederik, Adler, Charles H., Ossenkoppele, Rik, Beach, Thomas G., Hansson, Oskar

“…Lewy body (LB) diseases, characterized by the aggregation of misfolded α-synuclein proteins, exhibit notable clinical heterogeneity. This may be due to…”
Get full text

Submandibular Gland Biopsy for the Diagnosis of Parkinson Disease by Beach, Thomas G, Adler, Charles H, Dugger, Brittany N, Serrano, Geidy, Hidalgo, Jose, Henry-Watson, Jonette, Shill, Holly A, Sue, Lucia I, Sabbagh, Marwan N, Akiyama, Haruhiko

“…ABSTRACTThe clinical diagnosis of Parkinson disease (PD) is incorrect in 30% or more of subjects particularly at the time of symptom onset. Because Lewy-type…”
Get full text

Gender Differences in Alzheimer Disease: Brain Atrophy, Histopathology Burden, and Cognition by Filon, Jessica R., Intorcia, Anthony J., Sue, Lucia I., Vazquez Arreola, Elsa, Wilson, Jeffrey, Davis, Kathryn J., Sabbagh, Marwan N., Belden, Christine M., Caselli, Richard J., Adler, Charles H., Woodruff, Bryan K., Rapscak, Steven Z., Ahern, Geoffrey L., Burke, Anna D., Jacobson, Sandra, Shill, Holly A., Driver-Dunckley, Erika, Chen, Kewei, Reiman, Eric M., Beach, Thomas G., Serrano, Geidy E.

“…Multiple studies suggest that females are affected by Alzheimer disease (AD) more severely and more frequently than males. Other studies have failed to confirm…”
Get full text

Faster cognitive decline in dementia due to Alzheimer disease with clinically undiagnosed Lewy body disease by Malek-Ahmadi, Michael, Beach, Thomas G, Zamrini, Edward, Adler, Charles H, Sabbagh, Marwan N, Shill, Holly A, Jacobson, Sandra A, Belden, Christine M, Caselli, Richard J, Woodruff, Brian K, Rapscak, Steven Z, Ahern, Geoffrey L, Shi, Jiong, Caviness, John N, Driver-Dunckley, Erika, Mehta, Shyamal H, Shprecher, David R, Spann, Bryan M, Tariot, Pierre, Davis, Kathryn J, Long, Kathy E, Nicholson, Lisa R, Intorcia, Anthony, Glass, Michael J, Walker, Jessica E, Callan, Michael, Curry, Jasmine, Cutler, Brett, Oliver, Javon, Arce, Richard, Walker, Douglas G, Lue, Lih-Fen, Serrano, Geidy E, Sue, Lucia I, Chen, Kewei, Reiman, Eric M

“…Neuropathology has demonstrated a high rate of comorbid pathology in dementia due to Alzheimer's disease (ADD). The most common major comorbidity is Lewy body…”
Get full text

Clinicopathological Outcomes of Prospectively Followed Normal Elderly Brain Bank Volunteers by Dugger, Brittany N., Hentz, Joseph G., Adler, Charles H., Sabbagh, Marwan N., Shill, Holly A., Jacobson, Sandra, Caviness, John N., Belden, Christine, Driver-Dunckley, Erika, Davis, Kathryn J., Sue, Lucia I., Beach, Thomas G.

“…ABSTRACTExisting reports on the frequencies of neurodegenerative diseases are typically based on clinical diagnoses. We sought to determine these frequencies…”
Get full text

Pharmacotherapies for the Treatment of Progressive Supranuclear Palsy: A Narrative Review by Dunning, Elise E., Decourt, Boris, Zawia, Nasser H., Shill, Holly A., Sabbagh, Marwan N.

“…Progressive supranuclear palsy (PSP) is a neurodegenerative disorder resulting from the deposition of misfolded and neurotoxic forms of tau protein in specific…”
Get full text

Olfactory dysfunction in incidental Lewy body disease and Parkinson's disease by Driver-Dunckley, Erika, Adler, Charles H, Hentz, Joseph G, Dugger, Brittany N, Shill, Holly A, Caviness, John N, Sabbagh, Marwan N, Beach, Thomas G

“…Abstract Background Olfactory dysfunction in Parkinson's disease (PD) is well-established and may represent one of the earliest signs of the disease. Objective…”
Get full text

Lewy body pathology in Alzheimer's disease: A clinicopathological prospective study by Savica, Rodolfo, Beach, Thomas G., Hentz, Joseph G., Sabbagh, Marwan N., Serrano, Geidy E., Sue, Lucia I., Dugger, Brittany N., Shill, Holly A., Driver‐Dunckley, Erika, Caviness, John N., Mehta, Shyamal H., Jacobson, Sandra A., Belden, Christine M., Davis, Kathryn J., Zamrini, Edward, Shprecher, David R., Adler, Charles H.

“…Objective Identify clinical features predictive of Lewy body pathology in Alzheimer's disease (AD) patients in an ongoing longitudinal clinicopathologic study…”
Get full text

Incidental Lewy body disease: Clinical comparison to a control cohort by Adler, Charles H., Connor, Donald J., Hentz, Joseph G., Sabbagh, Marwan N., Caviness, John N., Shill, Holly A., Noble, Brie, Beach, Thomas G.

“…Limited clinical information has been published on cases pathologically diagnosed with incidental Lewy body disease (ILBD). Standardized, longitudinal movement…”
Get full text

Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment by Dugger, Brittany N, Davis, Kathryn, Malek-Ahmadi, Michael, Hentz, Joseph G, Sandhu, Shawn, Beach, Thomas G, Adler, Charles H, Caselli, Richard J, Johnson, Travis A, Serrano, Geidy E, Shill, Holly A, Belden, Christine, Driver-Dunckley, Erika, Caviness, John N, Sue, Lucia I, Jacobson, Sandra, Powell, Jessica, Sabbagh, Marwan N

“…Although there are studies investigating the pathologic origins of mild cognitive impairment (MCI), they have revolved around comparisons to normal elderly…”
Get full text