Search Results - "Shilkova, Olga"
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Effects of Mini-Spidroin Repeat Region on the Mechanical Properties of Artificial Spider Silk Fibers
Published in ACS omega (15-10-2024)“…Spiders can produce up to seven different types of silk, each with unique mechanical properties that stem from variations in the repetitive regions of spider…”
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2
Flow Cytometry of Mouse and Human Adipocytes for the Analysis of Browning and Cellular Heterogeneity
Published in Cell reports (Cambridge) (04-09-2018)“…Adipocytes, once considered simple lipid-storing cells, are rapidly emerging as complex cells with many biologically diverse functions. A powerful…”
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3
Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform
Published in Nature communications (15-08-2022)“…Recombinant spider silk proteins (spidroins) have multiple potential applications in development of novel biomaterials, but their multimodal and…”
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4
FNDC4 acts as an anti-inflammatory factor on macrophages and improves colitis in mice
Published in Nature communications (12-04-2016)“…FNDC4 is a secreted factor sharing high homology with the exercise-associated myokine irisin (FNDC5). Here we report that Fndc4 is robustly upregulated in…”
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5
P-TEFb, the super elongation complex and mediator regulate a subset of non-paused genes during early Drosophila embryo development
Published in PLoS genetics (01-02-2015)“…Positive Transcription Elongation Factor b (P-TEFb) is a kinase consisting of Cdk9 and Cyclin T that releases RNA Polymerase II (Pol II) into active…”
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6
Tyrosine residues mediate supercontraction in biomimetic spider silk
Published in Communications materials (12-04-2021)“…Water and humidity severely affect the material properties of spider major ampullate silk, causing the fiber to become plasticized, contract, swell and undergo…”
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Engineered Spider Silk Proteins for Biomimetic Spinning of Fibers with Toughness Equal to Dragline Silks
Published in Advanced functional materials (01-06-2022)“…Spider silk is the toughest fiber found in nature, and bulk production of artificial spider silk that matches its mechanical properties remains elusive…”
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8
Liquid–Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain
Published in Nano letters (28-06-2023)“…Many protein condensates can convert to fibrillar aggregates, but the underlying mechanisms are unclear. Liquid–liquid phase separation (LLPS) of spider silk…”
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9
Tuneable Recombinant Spider Silk Protein Hydrogels for Drug Release and 3D Cell Culture
Published in Advanced functional materials (28-08-2024)“…Hydrogels are useful drug release systems and tissue engineering scaffolds. However, synthetic hydrogels often require harsh gelation conditions and can…”
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Engineered Spider Silk Proteins for Biomimetic Spinning of Fibers with Toughness Equal to Dragline Silks (Adv. Funct. Mater. 23/2022)
Published in Advanced functional materials (01-06-2022)“…Engineered Spider Silk Protein In article number 2200986, Anna Rising and co‐workers present the impressive strength of spider silk fibers conferred by…”
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11
Separation of transcriptional repressor and activator functions in Drosophila HDAC3
Published in Development (Cambridge) (01-08-2023)“…The histone deacetylase HDAC3 is associated with the NCoR/SMRT co-repressor complex, and its canonical function is in transcriptional repression, but it can…”
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12
Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue
Published in Nature communications (20-05-2021)“…The proper functional interaction between different tissues represents a key component in systemic metabolic control. Indeed, disruption of endocrine…”
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13
P-TEFb, the Super Elongation Complex and Mediator Regulate a Subset of Non-paused Genes during Early Drosophila Embryo Development: e1004971
Published in PLoS genetics (01-02-2015)“…Positive Transcription Elongation Factor b (P-TEFb) is a kinase consisting of Cdk9 and Cyclin T that releases RNA Polymerase II (Pol II) into active…”
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