Search Results - "Shiiba, Ken‐ichi"
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Infiltration of CD40-positive tumor-associated macrophages indicates a favorable prognosis in colorectal cancer patients
Published in Hepato-gastroenterology (01-01-2013)“…Recently the role of tumor-associated macrophages (TAMs) on immunity has been variously discussed. We studied a series of cell surface antigens in TAMs in…”
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2
DUSP13B/TMDP inhibits stress-activated MAPKs and suppresses AP-1-dependent gene expression
Published in Molecular and cellular biochemistry (01-06-2011)“…The dual-specificity phosphatase (DUSP) 13 gene encodes two atypical DUSPs, DUSP13B/TMDP and DUSP13A/MDSP using alternative exons. DUSP13B protein is most…”
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3
Cancer-associated splicing variants of the CDCA1 and MSMB genes expressed in cancer cell lines and surgically resected gastric cancer tissues
Published in Surgery (2009)“…Background Alternative splicing is a molecular mechanism by which different combinations of exons can be alternatively spliced to produce different mRNA…”
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4
Introduction of antisense CD44s cDNA down‐regulates expression of overall CD44 isoforms and inhibits tumor growth and metastasis in highly metastatic colon carcinoma cells
Published in International journal of cancer (01-01-2001)“…We created antisense CD44 transfectants using LS174T, a colon adenocarcinoma cell line and assessed the effects of overall CD44 down‐regulation on colorectal…”
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5
Differing expression of MMPs‐1 and ‐9 and urokinase receptor between diffuse‐ and intestinal‐type gastric carcinoma
Published in International journal of cancer (19-02-1999)“…Gastric cancer is classified into intestinal and diffuse types, which exhibit different biological behavior. Urokinase‐type plasminogen activator (uPA), its…”
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6
Expression of thymidine phosphorylase by macrophages in colorectal cancer tissues
Published in World journal of gastroenterology : WJG (15-02-2004)“…AIM:To detect the thymidine phosphorylase (dThdPase) expression in human colorectal cancer tissues and cells.METHODS:Forty specimens resected from patients…”
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Novel function of MKP-5/DUSP10, a phosphatase of stress-activated kinases, on ERK-dependent gene expression, and upregulation of its gene expression in colon carcinomas
Published in Oncology reports (01-09-2012)“…Mitogen-activated protein kinase phosphatase 5 (MKP-5)/DUSP10 acts as a phosphatase of stress-activated kinases (JNK and p38), but its activity towards ERK has…”
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8
Effect of ileo-jejunal transposition on ileal longitudinal smooth muscle contractility in vitro in rats
Published in Journal of gastrointestinal surgery (01-12-2004)“…The aim of the present paper was to study the effects of ileo-jejunal transposition (IJT) on ileal contractile activity in vitro in rats. Male Sprague-Dawley…”
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9
Infiltration of CD14-positive macrophages at the invasive front indicates a favorable prognosis in colorectal cancer patients with lymph node metastasis
Published in Hepato-gastroenterology (01-03-2011)“…To clarify the distribution of CD14+ macrophages in colorectal cancer using flow cytometry and immunohistochemistry, and to elucidate the roles of CD14+…”
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10
Successful treatment of intraoperative heart failure caused by ampulla cardiomyopathy by intra-aortic balloon pumping and percutaneous cardiopulmonary support: report of a case
Published in Surgery today (Tokyo, Japan) (01-10-2005)“…An 82-year-old woman underwent total gastrectomy for advanced gastric cancer with invasion to the lower esophagus. Her blood pressure dropped alarmingly during…”
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Outcomes after Pylorus‐preserving Gastrectomy for Early Gastric Cancer: A Prospective Multicenter Trial
Published in World journal of surgery (01-09-2004)“…The aim of the present study was to compare in a prospective, multicenter trial the results early and late after pylorus‐preserving gastrectomy (PPG) versus…”
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12
Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay
Published in Cancer research (Chicago, Ill.) (15-06-2000)“…The tumor suppressor gene PTEN is frequently mutated in diverse human cancers and in autosomal dominant cancer predisposition disorders. Recent studies have…”
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13
Interleukin-12 administration is more effective for preventing metastasis than for inhibiting primary established tumors in a murine model of spontaneous hepatic metastasis
Published in Surgery today (Tokyo, Japan) (01-01-2002)“…The effect of interleukin-12 (IL-12) on tumor growth at the primary site and its therapeutic efficacy against metastasis were examined using a model of…”
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14
Comparison of False Negative Rates among Breast Cancer Screening Modalities with or without Mammography: Miyagi Trial
Published in Japanese Journal of Cancer Research (01-05-1995)“…False negative rates were compared in two screening modalities, physical examination with or without mammography, in an intervention study for women aged over…”
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New reconstructive procedure after intestinal resection for Crohn's disease: Modified side-to-side isoperistaltic anastomosis with double Heineke-Mikulicz procedure
Published in Diseases of the colon & rectum (01-06-2004)“…Although side-to-side isoperistaltic anastomosis is a useful strictureplasty technique when long segments of intestinal stenosis complicate Crohn's disease,…”
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Improved Detection Rate of Early Breast Cancer in Mass Screening Combined with Mammography
Published in Japanese Journal of Cancer Research (01-07-1993)“…A cohort study to compare mass screening with and without mammography was conducted in Miyagi Prefecture, Japan in order to establish whether the effectiveness…”
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17
CD44H Participates in the Intrahepatic Growth of Murine Colon 26 Adenocarcinoma Cells
Published in Cancer science (01-11-1998)“…The purpose of this study was to determine if CD44, a metastasis‐associated cell adhesion molecule, is involved in the hepatic colonization by murine colon 26…”
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Enhanced expression of lipocortin-1 as a new immunosuppressive protein in cancer patients and its influence on reduced in vitro peripheral blood lymphocyte response to mitogens
Published in Surgery today (Tokyo, Japan) (1997)“…To clarify the mechanism of immunosuppression in cancer-bearing hosts, the expression of lipocortin-1 (LC1), a new immunosuppressant, and its effects on the in…”
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Effect of steroid therapy for late dumping syndrome after total gastrectomy: Report of a case
Published in Digestive diseases and sciences (01-05-2004)Get full text
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Evidence for existence of oligoclonal tumor-infiltrating lymphocytes and predominant production of T helper 1/T cytotoxic 1 type cytokines in gastric and colorectal tumors
Published in International journal of oncology (01-07-2004)“…Tumor-infiltrating lymphocytes (TIL) play a central role in cellular immunity against tumor. We have revealed the characteristics of TILs in terms of T-cell…”
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