Search Results - "Shihan, Mahbubul H."

A simple method for quantitating confocal fluorescent images by Shihan, Mahbubul H., Novo, Samuel G., Le Marchand, Sylvain J., Wang, Yan, Duncan, Melinda K.

“…Western blotting (WB), enzyme-linked immunosorbent assay (ELISA) and flow cytometry (FC) have long been used to assess and quantitate relative protein…”
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AMPK stimulation inhibits YAP/TAZ signaling to ameliorate hepatic fibrosis by Shihan, Mahbubul H., Sharma, Sachin, Cable, Carson, Prathigudupu, Vijaya, Chen, Alina, Mattis, Aras N., Chen, Jennifer Y.

“…Hepatic fibrosis is driven by the activation of hepatic stellate cells (HSCs). The Hippo pathway and its effectors, YAP and TAZ, are key regulators of HSC…”
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The Immediate Early Response of Lens Epithelial Cells to Lens Injury by Novo, Samuel G, Faranda, Adam P, Shihan, Mahbubul H, Wang, Yan, Garg, Ananya, Duncan, Melinda K

“…Cataracts are treated by lens fiber cell removal followed by intraocular lens (IOL) implantation into the lens capsule. While effective, this procedure leaves…”
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αVβ8 integrin targeting to prevent posterior capsular opacification by Shihan, Mahbubul H, Novo, Samuel G, Wang, Yan, Sheppard, Dean, Atakilit, Amha, Arnold, Thomas D, Rossi, Nicole M, Faranda, Adam P, Duncan, Melinda K

“…Fibrotic posterior capsular opacification (PCO), a major complication of cataract surgery, is driven by transforming growth factor-β (TGF-β). Previously, αV…”
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Targeting acid ceramidase ameliorates fibrosis in mouse models of non-alcoholic steatohepatitis by Yu, Amy, Cable, Carson, Sharma, Sachin, Shihan, Mahbubul H., Mattis, Aras N., Mileva, Izolda, Hannun, Yusuf A., Duwaerts, Caroline C., Chen, Jennifer Y.

“…Non-alcoholic fatty liver disease (NAFLD) is a common cause of liver disease worldwide, and is characterized by the accumulation of fat in the liver…”
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Lens Epithelial Cells Initiate an Inflammatory Response Following Cataract Surgery by Jiang, Jian, Shihan, Mahbubul H, Wang, Yan, Duncan, Melinda K

“…Lens epithelial cell (LEC) conversion to myofibroblast is responsible for fibrotic cataract surgery complications including posterior capsular opacification…”
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The aging mouse lens transcriptome by Faranda, Adam P., Shihan, Mahbubul H., Wang, Yan, Duncan, Melinda K.

“…Abstract Age is a major risk factor for cataract (ARC). However, the influence of aging on the lens transcriptome is under studied. Lens epithelial (LEC) and…”
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Fibronectin has multifunctional roles in posterior capsular opacification (PCO) by Shihan, Mahbubul H., Kanwar, Mallika, Wang, Yan, Jackson, Erin E., Faranda, Adam P., Duncan, Melinda K.

“…Fibrotic posterior capsular opacification (PCO), one of the major complications of cataract surgery, occurs when lens epithelial cells (LCs) left behind post…”
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The effect of sex on the mouse lens transcriptome by Faranda, Adam P., Shihan, Mahbubul H., Wang, Yan, Duncan, Melinda K.

“…The transcriptome of mammalian tissues differs between males and females, and these differences can change across the lifespan, likely regulating known sexual…”
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Cataract surgeon viewpoints on the need for novel preventative anti-inflammatory and anti-posterior capsular opacification therapies by Shihan, Mahbubul H., Novo, Samuel G., Duncan, Melinda K.

“…Purpose: To determine cataract surgeon viewpoints on the efficacy of available therapies/preventatives for two common sequelae of cataract surgery:…”
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Spatiotemporal dynamics of canonical Wnt signaling during embryonic eye development and posterior capsular opacification (PCO) by Wang, Yichen, Mahesh, Priyha, Wang, Yan, Novo, Samuel G., Shihan, Mahbubul H., Hayward-Piatkovskyi, Brielle, Duncan, Melinda K.

“…The appropriate spatial and temporal regulation of canonical Wnt signaling is vital for eye development. However, the literature often conflicts on the…”
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The Regulation of Transforming Growth Factor Beta (TGFβ) Signaling in Posterior Capsular Opacification by Shihan, Mahbubul H

“…Posterior capsular opacification (PCO), one of the major complications of cataract surgery, occurs when lens epithelial cells (LCs) left behind post cataract…”
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