Search Results - "Shih-Houng Young"

Cardiovascular Effects of Pulmonary Exposure to Single-Wall Carbon Nanotubes by Zheng Li, Hulderman, Tracy, Salmen, Rebecca, Rebecca Chapman, Leonard, Stephen S., Shih-Houng Young, Anna Shvedova, Luster, Michael I., Simeonova, Petia P.

“…Background: Engineered nanosized materials, such as single-wall carbon nanotubes (SWCNT), are emerging as technologically important in different industries…”
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Interactive effects of cerium oxide and diesel exhaust nanoparticles on inducing pulmonary fibrosis by Ma, Jane Y.C., Young, Shih-Houng, Mercer, Robert R., Barger, Mark, Schwegler-Berry, Diane, Ma, Joseph K., Castranova, Vincent

“…Cerium compounds have been used as a fuel-borne catalyst to lower the generation of diesel exhaust particles (DEPs), but are emitted as cerium oxide…”
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Factoring-in agglomeration of carbon nanotubes and nanofibers for better prediction of their toxicity versus asbestos by Murray, Ashley R, Kisin, Elena R, Tkach, Alexey V, Yanamala, Naveena, Mercer, Robert, Young, Shih-Houng, Fadeel, Bengt, Kagan, Valerian E, Shvedova, Anna A

“…Carbon nanotubes (CNT) and carbon nanofibers (CNF) are allotropes of carbon featuring fibrous morphology. The dimensions and high aspect ratio of CNT and CNF…”
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Direct Effects of Carbon Nanotubes on Dendritic Cells Induce Immune Suppression Upon Pulmonary Exposure by Tkach, Alexey V, Shurin, Galina V, Shurin, Michael R, Kisin, Elena R, Murray, Ashley R, Young, Shih-Houng, Star, Alexander, Fadeel, Bengt, Kagan, Valerian E, Shvedova, Anna A

“…Pharyngeal aspiration of single-walled carbon nanotubes (SWCNTs) caused inflammation, pulmonary damage, and an altered cytokine network in the lung. Local…”
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Titanium Dioxide (TiO2) Nanoparticles Induce JB6 Cell Apoptosis Through Activation of the Caspase-8/Bid and Mitochondrial Pathways by Zhao, Jinshun, Bowman, Linda, Zhang, Xingdong, Vallyathan, Val, Young, Shih-Houng, Castranova, Vincent, Ding, Min

“…Titanium dioxide (TiO 2 ), a commercially important material, is used in a wide variety of products. Although TiO 2 is generally regarded as nontoxic, the…”
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Molecular mechanisms of pulmonary response progression in crystalline silica exposed rats by Sellamuthu, Rajendran, Umbright, Christina, Roberts, Jenny R., Young, Shih-Houng, Richardson, Diana, McKinney, Walter, Chen, Bean T., Li, Shengqiao, Kashon, Michael, Joseph, Pius

“…An understanding of the mechanisms underlying diseases is critical for their prevention. Excessive exposure to crystalline silica is a risk factor for…”
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Blood Gene Expression Profiling Detects Silica Exposure and Toxicity by Sellamuthu, Rajendran, Umbright, Christina, Roberts, Jenny R., Chapman, Rebecca, Young, Shih-Houng, Richardson, Diana, Leonard, Howard, McKinney, Walter, Chen, Bean, Frazer, David, Li, Shengqiao, Kashon, Michael, Joseph, Pius

“…Blood gene expression profiling was investigated as a minimally invasive surrogate approach to detect silica exposure and resulting pulmonary toxicity. Rats…”
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Identification of Systemic Markers from A Pulmonary Carbon Nanotube Exposure by Erdely, Aaron, Liston, Angie, Salmen-Muniz, Rebecca, Hulderman, Tracy, Young, Shih-Houng, Zeidler-Erdely, Patti C., Castranova, Vincent, Simeonova, Petia P.

“…Objective: Interest exists for early monitoring of worker exposure to engineered nanomaterials. Here, we highlight quantitative systemic markers of early…”
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Performance evaluation of cytometric bead assays for the measurement of lung cytokines in two rodent models by Young, Shih-Houng, Antonini, James M., Roberts, Jenny R., Erdely, Aaron D., Zeidler-Erdely, Patti C.

“…There is a growing demand for a cost-effective, efficient, and high-throughput method for measuring cytokines. Currently, many studies are using flow…”
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Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fume by Zeidler-Erdely, Patti C, Kashon, Michael L, Battelli, Lori A, Young, Shih-Houng, Erdely, Aaron, Roberts, Jenny R, Reynolds, Steven H, Antonini, James M

“…Welding fume has been categorized as "possibly carcinogenic" to humans. Our objectives were to characterize the lung response to carcinogenic and…”
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Multiwalled Carbon Nanotubes Induce a Fibrogenic Response by Stimulating Reactive Oxygen Species Production, Activating NF-κB Signaling, and Promoting Fibroblast-to-Myofibroblast Transformation by He, Xiaoqing, Young, Shih-Houng, Schwegler-Berry, Diane, Chisholm, William P, Fernback, Joseph E, Ma, Qiang

“…Carbon nanotubes (CNTs) are novel materials with unique electronic and mechanical properties. The extremely small size, fiberlike shape, large surface area,…”
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Adjuvant effect of zymosan after pulmonary treatment in a mouse ovalbumin allergy model by Young, Shih-Houng, Wolfarth, Michael G., Roberts, Jenny R., Kashon, Michael L., Antonini, James M.

“…ABSTRACTAn association has been observed between indoor mold contamination and lung allergy and asthma. This relationship is not fully understood. 1→3-β-Glucan…”
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A Comparison of the Pulmonary Inflammatory Potential of Different Components of Yeast Cell Wall by Young, Shih-Houng, Ostroff, Gary R., Zeidler-Erdely, Patti C., Roberts, Jenny R., Antonini, James M., Castranova, Vincent

“…1→3-β-Glucan has been associated with pulmonary inflammation induced by exposure to fungal or yeast cell wall dust. 1→3-β-Glucan is the major cell wall…”
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Genotoxicity of multi-walled carbon nanotubes at occupationally relevant doses by Siegrist, Katelyn J, Reynolds, Steven H, Kashon, Michael L, Lowry, David T, Dong, Chenbo, Hubbs, Ann F, Young, Shih-Houng, Salisbury, Jeffrey L, Porter, Dale W, Benkovic, Stanley A, McCawley, Michael, Keane, Michael J, Mastovich, John T, Bunker, Kristin L, Cena, Lorenzo G, Sparrow, Mark C, Sturgeon, Jacqueline L, Dinu, Cerasela Zoica, Sargent, Linda M

“…Carbon nanotubes are commercially-important products of nanotechnology; however, their low density and small size makes carbon nanotube respiratory exposures…”
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Lung toxicity and biodistribution of Cd/Se-ZnS quantum dots with different surface functional groups after pulmonary exposure in rats by Roberts, Jenny R, Antonini, James M, Porter, Dale W, Chapman, Rebecca S, Scabilloni, James F, Young, Shih-Houng, Schwegler-Berry, Diane, Castranova, Vincent, Mercer, Robert R

“…The potential use of quantum dots (QD) in biomedical applications, as well as in other systems that take advantage of their unique physiochemical properties,…”
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Pulmonary toxicity and global gene expression changes in response to sub-chronic inhalation exposure to crystalline silica in rats by Umbright, Christina, Sellamuthu, Rajendran, Roberts, Jenny R., Young, Shih-Houng, Richardson, Diana, Schwegler-Berry, Diane, McKinney, Walter, Chen, Bean, Gu, Ja Kook, Kashon, Michael, Joseph, Pius

“…Exposure to crystalline silica results in serious adverse health effects, most notably, silicosis. An understanding of the mechanism(s) underlying…”
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Sodium hydroxide-induced conformational change in schizophyllan detected by the fluorescence dye, aniline blue by Young, Shih-Houng, Jacobs, Robert R

“…Molecular conformation is considered to be an important factor in determining the biological activity of glucans; however, a simple method to detect the…”
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Oxidative Stress and Dermal Toxicity of Iron Oxide Nanoparticles In Vitro by Murray, Ashley R., Kisin, Elena, Inman, Alfred, Young, Shih-Houng, Muhammed, Mamoun, Burks, Terrance, Uheida, Abdusalam, Tkach, Alexey, Waltz, Micah, Castranova, Vincent, Fadeel, Bengt, Kagan, Valerian E., Riviere, Jim E., Monteiro-Riviere, Nancy, Shvedova, Anna A.

“…A number of commercially available metal/metal oxide nanoparticles (NPs) such as superparamagnetic iron oxide (SPION) are utilized by the medical field for a…”
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Comparison of cell counting methods in rodent pulmonary toxicity studies: automated and manual protocols and considerations for experimental design by Zeidler-Erdely, Patti C., Antonini, James M., Meighan, Terence G., Young, Shih-Houng, Eye, Tracy J., Hammer, Mary Ann, Erdely, Aaron

“…Pulmonary toxicity studies often use bronchoalveolar lavage (BAL) to investigate potential adverse lung responses to a particulate exposure. The BAL cellular…”
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Oxidative stress and reduced responsiveness of challenged circulating leukocytes following pulmonary instillation of metal-rich particulate matter in rats by Erdely, Aaron, Antonini, James M, Young, Shih-Houng, Kashon, Michael L, Gu, Ja K, Hulderman, Tracy, Salmen, Rebecca, Meighan, Terence, Roberts, Jenny R, Zeidler-Erdely, Patti C

“…Welding fume is an exposure that consists of a mixture of metal-rich particulate matter with gases (ozone, carbon monoxide) and/or vapors (VOCs). Data suggests…”
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