Search Results - "Shih, William M."
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Virus-Inspired Membrane Encapsulation of DNA Nanostructures To Achieve In Vivo Stability
Published in ACS nano (27-05-2014)“…DNA nanotechnology enables engineering of molecular-scale devices with exquisite control over geometry and site-specific functionalization. This capability…”
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Three-Dimensional Structures Self-Assembled from DNA Bricks
Published in Science (American Association for the Advancement of Science) (30-11-2012)“…We describe a simple and robust method to construct complex three-dimensional (3D) structures by using short synthetic DNA strands that we call "DNA bricks."…”
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3
Self-assembly of size-controlled liposomes on DNA nanotemplates
Published in Nature chemistry (01-05-2016)“…Artificial lipid-bilayer membranes are valuable tools for the study of membrane structure and dynamics. For applications such as the study of vesicular…”
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4
Addressing the Instability of DNA Nanostructures in Tissue Culture
Published in ACS nano (23-09-2014)“…DNA nanotechnology is an advanced technique that could contribute diagnostic, therapeutic, and biomedical research devices to nanomedicine. Although such…”
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5
Programming Self-Assembly of DNA Origami Honeycomb Two-Dimensional Lattices and Plasmonic Metamaterials
Published in Journal of the American Chemical Society (22-06-2016)“…Scaffolded DNA origami has proven to be a versatile method for generating functional nanostructures with prescribed sub-100 nm shapes. Programming DNA-origami…”
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6
Oligolysine-based coating protects DNA nanostructures from low-salt denaturation and nuclease degradation
Published in Nature communications (31-05-2017)“…DNA nanostructures have evoked great interest as potential therapeutics and diagnostics due to ease and robustness of programming their shapes, site-specific…”
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7
Modulation of the Cellular Uptake of DNA Origami through Control over Mass and Shape
Published in Nano letters (13-06-2018)“…Designer nanoparticles with controlled shapes and sizes are increasingly popular vehicles for therapeutic delivery due to their enhanced cell-delivery…”
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Prescribed nanoparticle cluster architectures and low-dimensional arrays built using octahedral DNA origami frames
Published in Nature nanotechnology (01-07-2015)“…Three-dimensional mesoscale clusters that are formed from nanoparticles spatially arranged in pre-determined positions can be thought of as mesoscale analogues…”
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Selective Nascent Polymer Catch‐and‐Release Enables Scalable Isolation of Multi‐Kilobase Single‐Stranded DNA
Published in Angewandte Chemie International Edition (15-01-2018)“…Scalable methods currently are lacking for isolation of long ssDNA, an important material for numerous biotechnological applications. Conventional biomolecule…”
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Using DNA to program the self-assembly of colloidal nanoparticles and microparticles
Published in Nature reviews. Materials (01-03-2016)“…DNA is not just the stuff of our genetic code; it is also a means to design self-assembling materials. Grafting DNA onto nano- and microparticles can, in…”
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11
Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching
Published in Nature (London) (04-08-2011)“…Mitochondrial proton transport The transport of small molecules across the inner mitochondrial membrane is catalysed by a large family of membrane proteins…”
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Multi-micron crisscross structures grown from DNA-origami slats
Published in Nature nanotechnology (01-03-2023)“…Living systems achieve robust self-assembly across a wide range of length scales. In the synthetic realm, nanofabrication strategies such as DNA origami have…”
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13
Regulation at a distance of biomolecular interactions using a DNA origami nanoactuator
Published in Nature communications (18-03-2016)“…The creation of nanometre-sized structures that exhibit controllable motions and functions is a critical step towards building nanomachines. Recent…”
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14
Precise pitch-scaling of carbon nanotube arrays within three-dimensional DNA nanotrenches
Published in Science (American Association for the Advancement of Science) (22-05-2020)“…Precise fabrication of semiconducting carbon nanotubes (CNTs) into densely aligned evenly spaced arrays is required for ultrascaled technology nodes. We report…”
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15
Self-assembly of three-dimensional prestressed tensegrity structures from DNA
Published in Nature nanotechnology (01-07-2010)“…Tensegrity, or tensional integrity, is a property of a structure indicating a reliance on a balance between components that are either in pure compression or…”
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16
Robust nucleation control via crisscross polymerization of highly coordinated DNA slats
Published in Nature communications (19-03-2021)“…Natural biomolecular assemblies such as actin filaments or microtubules can exhibit all-or-nothing polymerization in a kinetically controlled fashion. The…”
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17
DNA-nanotube-induced alignment of membrane proteins for NMR structure determination
Published in Proceedings of the National Academy of Sciences - PNAS (17-04-2007)“…Membrane proteins are encoded by 20-35% of genes but represent <1% of known protein structures to date. Thus, improved methods for membrane-protein structure…”
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Membrane-Assisted Growth of DNA Origami Nanostructure Arrays
Published in ACS nano (28-04-2015)“…Biological membranes fulfill many important tasks within living organisms. In addition to separating cellular volumes, membranes confine the space available to…”
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Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA
Published in Nature chemistry (01-10-2012)“…The identification and differentiation of a large number of distinct molecular species with high temporal and spatial resolution is a major challenge in…”
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20
Single-molecule super-resolution imaging of chromosomes and in situ haplotype visualization using Oligopaint FISH probes
Published in Nature communications (12-05-2015)“…Fluorescence in situ hybridization (FISH) is a powerful single-cell technique for studying nuclear structure and organization. Here we report two advances in…”
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