Search Results - "Shih, Heather"

Aberrant Cdk5 Activation by p25 Triggers Pathological Events Leading to Neurodegeneration and Neurofibrillary Tangles by Cruz, Jonathan C., Tseng, Huang-Chun, Goldman, Joseph A., Shih, Heather, Tsai, Li-Huei

“…Cyclin-dependent kinase 5 (Cdk5) and its regulatory subunit p35 are integral players in the proper development of the mammalian central nervous system…”
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Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members by Lake, Andrew C, Sun, Ying, Li, Jian-Liang, Kim, Jae Eun, Johnson, Jeremy W, Li, Dongmei, Revett, Tracy, Shih, Heather H, Liu, Wei, Paulsen, Janet E, Gimeno, Ruth E

“…Adiponutrin and a related protein, adipocyte triglyceride lipase (ATGL; also known as Desnutrin), were recently described as adipocyte-specific proteins with…”
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An Ultra-specific Avian Antibody to Phosphorylated Tau Protein Reveals a Unique Mechanism for Phosphoepitope Recognition by Shih, Heather H., Tu, Chao, Cao, Wei, Klein, Anne, Ramsey, Renee, Fennell, Brian J., Lambert, Matthew, Ní Shúilleabháin, Deirdre, Autin, Bénédicte, Kouranova, Eugenia, Laxmanan, Sri, Braithwaite, Steven, Wu, Leeying, Ait-Zahra, Mostafa, Milici, Anthony J., Dumin, Jo Ann, LaVallie, Edward R., Arai, Maya, Corcoran, Christopher, Paulsen, Janet E., Gill, Davinder, Cunningham, Orla, Bard, Joel, Mosyak, Lydia, Finlay, William J.J.

“…Highly specific antibodies to phosphoepitopes are valuable tools to study phosphorylation in disease states, but their discovery is largely empirical, and the…”
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CRP is a novel ligand for the oxidized LDL receptor LOX-1 by Shih, Heather H, Zhang, Songwen, Cao, Wei, Hahn, Ashleigh, Wang, Juan, Paulsen, Janet E, Harnish, Douglas C

“…C-reactive protein (CRP) is a risk factor for cardiovascular events and functions to amplify vascular inflammation through promoting endothelial dysfunction…”
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Serine 732 Phosphorylation of FAK by Cdk5 Is Important for Microtubule Organization, Nuclear Movement, and Neuronal Migration by Xie, Zhigang, Sanada, Kamon, Samuels, Benjamin Adam, Shih, Heather, Tsai, Li-Huei

“…The serine/threonine kinase Cdk5 plays an essential role in neuronal positioning during corticogenesis, but the underlying mechanisms are unknown. In…”
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LOX-1-dependent transcriptional regulation in response to oxidized LDL treatment of human aortic endothelial cells by Mattaliano, Mark D, Huard, Christine, Cao, Wei, Hill, Andrew A, Zhong, Wenyan, Martinez, Robert V, Harnish, Doug C, Paulsen, Janet E, Shih, Heather H

“…Oxidized low-density lipoprotein (OxLDL) has been implicated as a proatherogenic factor with a pathological role in the induction of endothelial dysfunction…”
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Characterization of the immunoglobulin repertoire of the spiny dogfish (Squalus acanthias) by Smith, Lauren E., Crouch, Kathryn, Cao, Wei, Müller, Mischa R., Wu, Leeying, Steven, John, Lee, Michael, Liang, Musen, Flajnik, Martin F., Shih, Heather H., Barelle, Caroline J., Paulsen, Janet, Gill, Davinder S., Dooley, Helen

“…► We characterize the immunoglobulin repertoire of spiny dogfish. ► Ig isotypes and isoforms are highly conserved across the cartilaginous fish. ► Spiny…”
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Inhibition of Gluconeogenesis through Transcriptional Activation of EGR1 and DUSP4 by AMP-activated Kinase by Berasi, Stephen P., Huard, Christine, Li, Dongmei, Shih, Heather H., Sun, Ying, Zhong, Wenyan, Paulsen, Janet E., Brown, Eugene L., Gimeno, Ruth E., Martinez, Robert V.

“…Increased hepatic gluconeogenesis is an important contributor to the fasting hyperglycemia found in Type 2 diabetic patients. Low energy states activate the…”
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ROCK2 associates with lectin-like oxidized LDL receptor-1 and mediates oxidized LDL-induced IL-8 production by Mattaliano, Mark D, Wooters, Joe, Shih, Heather H, Paulsen, Janet E

“…Oxidatively modified low-density lipoprotein (OxLDL) is a contributing factor of endothelial dysfunction, an early cellular event during atherogenesis. In…”
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Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis by Clerin, Valerie, Shih, Heather H, Deng, Nanhua, Hebert, Gustave, Resmini, Christine, Shields, Kathleen M, Feldman, Jeffrey L, Winkler, Aaron, Albert, Leo, Maganti, Vasu, Wong, Anthony, Paulsen, Janet E, Keith, James C, Vlasuk, George P, Pittman, Debra D

“…Abstract Objective The present study was conducted to characterize the expression of the cysteine protease legumain in murine and human atherosclerotic…”
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Oligomerization is required for the activity of recombinant soluble LOX-1 by Cao, Wei, Calabro, Valerie, Root, Adam, Yan, Grace, Lam, Khetemenee, Olland, Stephane, Sanford, Jocelyn, Robak, Angela, Zollner, Richard, Lu, Zhijian, Ait-Zahra, Mostafa, Agostinelli, Rita, Tchistiakova, Lioudmila, Gill, Davinder, Harnish, Douglas, Paulsen, Janet, Shih, Heather H

“…LOX-1 is a scavenger receptor that functions as the primary receptor for oxidized low-density lipoprotein (OxLDL) in endothelial cells. The binding of OxLDL to…”
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SLIC-1/sorting nexin 20: A novel sorting nexin that directs subcellular distribution of PSGL-1 by Schaff, Ulrich Y, Shih, Heather H, Lorenz, Meike, Sako, Dianne, Kriz, Ron, Milarski, Kim, Bates, Brian, Tchernychev, Boris, Shaw, Gray D, Simon, Scott I

“…P-Selectin glycoprotein ligand-1 (PSGL-1) is a mucin-like glycoprotein expressed on the surface of leukocytes that serves as the major ligand for the selectin…”
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Transcriptional profiling of C2C12 myotubes in response to SHIP2 depletion and insulin stimulation by Huard, Christine, Martinez, Robert V., Ross, Cindy, Johnson, Jeremy W., Zhong, Wenyan, Hill, Andrew A., Kim, Richard, Paulsen, Janet E., Shih, Heather H.

“…Phosphoinositide lipids generated at the cell membrane are a key component of a variety of signaling pathways. Among several inositol phosphatases that…”
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Randomized Study of Rivaroxaban vs Placebo on Disease Progression and Symptoms Resolution in High-Risk Adults With Mild Coronavirus Disease 2019 by Ananworanich, Jintanat, Mogg, Robin, Dunne, Michael W, Bassyouni, Mohamed, David, Consuela Vera, Gonzalez, Erika, Rogalski-Salter, Taryn, Shih, Heather, Silverman, Jared, Medema, Jeroen, Heaton, Penny

“…Abstract Background Severe acute respiratory syndrome coronavirus 2 infection may be associated with a prothrombotic state, predisposing patients for a…”
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Regulation of Differentiation by HBP1, a Target of the Retinoblastoma Protein by Shih, Heather H., Tevosian, Sergei G., Yee, Amy S.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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HMG Box Transcriptional Repressor HBP1 Maintains a Proliferation Barrier in Differentiated Liver Tissue by Shih, Heather H., Xiu, Mei, Berasi, Stephen P., Sampson, Ellen M., Leiter, Andrew, Paulson, K. Eric, Yee, Amy S.

“…ERRATUM ( vol. 21 , p. 7535 ) Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious…”
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Activation and repression of p21WAF1/CIP1 transcription by RB binding proteins by GARTEL, A. L, GOUFMAN, E, TEVOSIAN, S. G, SHIH, H, YEE, A. S, TYNER, A. L

“…The Cdk inhibitor p21WAF1/CIP1 is a negative regulator of the cell cycle, although its expression is induced by a number of mitogens that promote cell…”
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Primary sequence determination of a monoclonal antibody against α-synuclein using a novel mass spectrometry-based approach by Sousa, Eric, Olland, Stephane, Shih, Heather H., Marquette, Kim, Martone, Robert, Lu, Zhijian, Paulsen, Janet, Gill, Davinder, He, Tao

“…Use of visualization tool to aid identification of CDR-containing peptides after A-8 modification and trypsin digestion. [Display omitted] ► A novel mass…”
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Trivalent counterion condensation on DNA measured by pulse gel electrophoresis by Li, Anzhi Z., Qi, Lai Jun, Shih, Heather H., Marx, Kenneth A.

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HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family by Tevosian, S G, Shih, H H, Mendelson, K G, Sheppard, K A, Paulson, K E, Yee, A S

“…A prominent feature of cell differentiation is the initiation and maintenance of an irreversible cell cycle arrest with the complex involvement of the…”
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