Search Results - "Shih, Angela R"
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Updates on spread through air spaces (STAS) in lung cancer
Published in Histopathology (01-08-2020)“…Air space invasion of tumours, particularly spread through air spaces (STAS), is a relatively recent concept that has been identified as a novel mechanism of…”
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Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma
Published in Cancer cell (13-08-2018)“…Hürthle cell carcinoma of the thyroid (HCC) is a form of thyroid cancer recalcitrant to radioiodine therapy that exhibits an accumulation of mitochondria. We…”
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Clinicopathologic characteristics of poorly differentiated chordoma
Published in Modern pathology (01-08-2018)“…Chordoma is a rare malignant tumor of bone with high morbidity and mortality. Recently, aggressive pediatric poorly differentiated chordoma with SMARCB1 loss…”
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4
Early loss of mitochondrial complex I and rewiring of glutathione metabolism in renal oncocytoma
Published in Proceedings of the National Academy of Sciences - PNAS (03-07-2018)“…Renal oncocytomas are benign tumors characterized by a marked accumulation of mitochondria. We report a combined exome, transcriptome, and metabolome analysis…”
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5
The soft palate is an important site of adaptation for transmissible influenza viruses
Published in Nature (London) (01-10-2015)“…Efficient airborne transmission of influenza viruses between humans is associated with use of α2,6-linked sialic acids, not α2,3-linked sialic acids; however,…”
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6
Molecular characteristics of poorly differentiated chordoma
Published in Genes chromosomes & cancer (01-11-2019)“…Pediatric poorly differentiated chordoma is a subtype of chordoma with a much more aggressive clinical course and has been characterized by loss of SMARCB1…”
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Problems in the reproducibility of classification of small lung adenocarcinoma: an international interobserver study
Published in Histopathology (01-11-2019)“…Aims The 2015 WHO classification for lung adenocarcinoma (ACA) provides criteria for adenocarcinoma in situ (AIS), minimally invasive adenocarcinoma (MIA) and…”
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Immunohistochemistry for histone H3G34W and H3K36M is highly specific for giant cell tumor of bone and chondroblastoma, respectively, in FNA and core needle biopsy
Published in Cancer cytopathology (01-08-2018)“…BACKGROUND Diagnosing giant cell‐rich bone tumors can be challenging on limited biopsies. H3 histone family member 3A (H3F3A) (G34W/V/R/L) mutations are…”
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Practical application and validation of the 2018 ATS/ERS/JRS/ALAT and Fleischner Society guidelines for the diagnosis of idiopathic pulmonary fibrosis
Published in Respiratory research (26-04-2021)“…Accurate diagnosis of idiopathic pulmonary fibrosis (IPF) is essential to inform prognosis and treatment. In 2018, the ATS/ERS/JRS/ALAT and Fleischner Society…”
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10
A targetable ‘rogue’ neutrophil-subset, [CD11b+DEspR+] immunotype, is associated with severity and mortality in acute respiratory distress syndrome (ARDS) and COVID-19-ARDS
Published in Scientific reports (04-04-2022)“…Neutrophil-mediated secondary tissue injury underlies acute respiratory distress syndrome (ARDS) and progression to multi-organ-failure (MOF) and death,…”
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COVID-19: gastrointestinal and hepatobiliary manifestations
Published in Human pathology (01-02-2023)“…SARS-CoV-2 is the viral agent of COVID-19, a pandemic that surfaced in 2019. Although predominantly a respiratory ailment, patients with COVID-19 can have…”
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Case 3-2022: A 14-Year-Old Boy with Fever, Joint Pain, and Abdominal Cramping
Published in The New England journal of medicine (27-01-2022)“…A 14-year-old boy was admitted with fatigue, fever, joint pain, abdominal cramping, and diarrhea. He had been well until 2 weeks earlier, when fatigue and…”
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Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection
Published in Nature communications (09-12-2020)“…The relationship of SARS-CoV-2 pulmonary infection and severity of disease is not fully understood. Here we show analysis of autopsy specimens from 24 patients…”
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Nonconventional dysplasia in patients with inflammatory bowel disease and colorectal carcinoma: a multicenter clinicopathologic study
Published in Modern pathology (01-05-2020)“…Several types of nonconventional dysplasia have been recently described in inflammatory bowel disease (IBD). However, strict morphologic criteria are lacking,…”
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Lung Histopathology in Coronavirus Disease 2019 as Compared With Severe Acute Respiratory Sydrome and H1N1 Influenza: A Systematic Review
Published in Chest (01-01-2021)“…Patients with severe coronavirus disease 2019 (COVID-19) have respiratory failure with hypoxemia and acute bilateral pulmonary infiltrates, consistent with…”
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Cytomegalovirus Hepatitis in Allograft Livers May Show Histologic Features of Acute Cellular Rejection
Published in Archives of pathology & laboratory medicine (1976) (01-06-2023)“…Cytomegalovirus (CMV) hepatitis in allograft livers is an important infectious complication, with histology that historically has been described to overlap…”
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Case 35-2024: A Newborn with Hypoxemia and a Lung Opacity
Published in The New England journal of medicine (14-11-2024)“…A full-term infant was admitted to the neonatal intensive care unit for hypoxemic respiratory failure. During the third week, a chest radiograph showed a…”
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Persistent Cholestatic Injury and Secondary Sclerosing Cholangitis in COVID-19 Patients
Published in Archives of pathology & laboratory medicine (1976) (01-10-2022)“…Coronavirus disease 2019 (COVID-19) has been associated with liver injury, and a small subset of patients recovering from severe disease have shown persistent…”
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Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity
Published in Developmental cell (26-03-2018)“…We show that the loss or gain of transcription factor programs that govern embryonic cell-fate specification is associated with a form of tumor plasticity…”
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Trimethoprim-Sulfamethoxazole-associated Fulminant Respiratory Failure in Children and Young Adults
Published in American journal of respiratory and critical care medicine (01-04-2021)Get full text
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