Search Results - "Shigemasa, K."

Expression of matrix metalloproteinases (MMP-2, MMP-9, MT1-MMP) and their inhibitors (TIMP-1, TIMP-2) in common epithelial tumors of the ovary by Sakata, K, Shigemasa, K, Nagai, N, Ohama, K

“…Matrix metalloproteinases (MMPs) are known to play an important role in cancer cell invasion by mediating the degradation of extracellular matrix proteins. The…”
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Inhibition of telomerase activity and cell proliferation by a reverse transcriptase inhibitor in gynaecological cancer cell lines by Murakami, J, Nagai, N, Shigemasa, K, Ohama, K

“…Telomerase is a ribonucleoprotein which has a RNA template to bind and extend telomere ends, so prolonging the life of tumour cells. The aim of this study was…”
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Transmembrane serine protease TADG-15 (ST14/Matriptase/MT-SP1): expression and prognostic value in ovarian cancer by TANIMOTO, H, SHIGEMASA, K, TIAN, X, GU, L, BEARD, J. B, SAWASAKI, T, O'BRIEN, T. J

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p27, cyclin E, and CDK2 expression in normal and cancerous endometrium by Oshita, T, Shigemasa, K, Nagai, N, Ohama, K

“…The objective was to investigate the immunohistochemical expression of p27, cyclin E, and CDK2 in normal and cancerous endometrium. Expression of p27 in…”
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Epitopes on CA 125 from cervical mucus and ascites fluid and characterization of six new antibodies. Third report from the ISOBM TD-1 workshop by Nustad, K, Lebedin, Y, Lloyd, K O, Shigemasa, K, de Bruijn, H W A, Jansson, B, Nilsson, O, Olsen, K H, O'Brien, T J

“…CA 125 is found in body fluids in a variety of molecular weight forms. The largest species are found in normal abdominal fluid and cervical mucus. The present…”
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Underexpression of cyclin-dependent kinase inhibitor p27 is associated with poor prognosis in serous ovarian carcinomas by Shigemasa, K, Shiroyama, Y, Sawasaki, T, Fujii, T, Nagai, N, Parmley, T H, O'Brien, T J, Ohama, K

“…Reduced expression of a cyclin-dependent kinase inhibitor, p27, has been reported to be associated with poor prognosis in several human cancers. The aim of…”
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Experience of chest wall reconstruction with newly developed material by Osawa, H, Nishii, T, Suzuki, Y, Numata, M, Shigemasa, K, Tanabe, H, Tani, K, Shiraishi, R, Katayama, K, Nakagawa, A, Jin, Y, Yoshimura, N

“…After the chest wall resection, its reconstruction is often needed. A 45-year-old male lung adenocarcinoma patient with chest wall invasion underwent upper…”
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Gene expression and immunohistochemical localization of decorin and biglycan in association with early bone formation in the developing mandible by Kamiya, Naoko, Shigemasa, Kayoko, Takagi, Minoru

“…We investigated the expression of the small proteoglycans, decorin and biglycan, which are associated with osteoblast differentiation, and how this relates to…”
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Adenovirus-mediated p16 gene transfer changes the sensitivity to taxanes and Vinca alkaloids of human ovarian cancer cells by Kawakami, Y, Hama, S, Hiura, M, Nogawa, T, Chiba, T, Yokoyama, T, Takashima, S, Tajiri, H, Eguchi, K, Nagai, N, Shigemasa, K, Ohama, K, Kurisu, K, Heike, Y

“…Deletions and point mutations of the p16 gene are detectable in more than 50% of ovarian cancer cells. In this study, we examined the effect of p16 gene…”
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Expression of the protease inhibitor antileukoprotease and the serine protease stratum corneum chymotryptic enzyme (SCCE) is coordinated in ovarian tumors by Shigemasa, K, Tanimoto, H, Underwood, L J, Parmley, T H, Arihiro, K, Ohama, K, O'Brien, T J

“…We have previously reported that the stratum corneum chymotryptic enzyme (SCCE) is overexpressed in ovarian cancers and that SCCE has potential as a useful…”
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Expression of the farnesyltransferase β-subunit gene in human ovarian carcinoma : Correlation to K-ras mutation by TANIMOTO, H, MEHTA, K. D, PARMLEY, T. H, SHIGEMASA, K, PARHAM, G. P, CLARKE, J, O'BRIEN, T. J

“…The ras signaling protein requires a posttranslational modification to localize it to the inner surface of plasma membrane. In this state it can behave as a…”
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Clinical implications of mRNA expression of KAI1 in ovarian cancer with or without metastasis by Shigemasa, K., Nagai, N., Ohama, K., Arihiro, K., Fujii, T.

“…Background. KAI1 is a potential metastasis suppressor gene for prostate cancer. Decreased expression of KAI1 mRNA has been shown to be associated with the…”
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895 Invasive human bladder tumor cells form invadopodia that is initiated by macular expression of formin-binding protein(FBP) 17 by Hayato, Y, Mihoko, S, Tohru, Y, Akiko, O, Shingo, H, Shigemasa, K, Takahiro, Y, Yasuhiro, H, Takuya, K, Noritaka, K, Hisao, S, Tomihisa, F, Shigeru, T, Chikara, O

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A case of uterine cervical cancer in which UFT was an effective preoperative treatment by Nagai, N, Oshita, T, Shigemasa, K, Ohama, K, Takehara, K, Miyaoka, S

“…We report a case in which UFT was effective as a preoperative treatment for stage II b cervical cancer. The patient was a 66-year-old female whose chief…”
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Relative expression levels of Th1 and Th2 cytokine mRNA are independent prognostic factors in patients with ovarian cancer by Kusuda, Tomoyo, Shigemasa, Kazushi, Arihiro, Koji, Fujii, Tsuneo, Nagai, Nobutaka, Ohama, Koso

“…The aim of the present study was to examine mRNA expression levels of Th1 (TNF-alpha , IFN-gamma, and IL-12p40) and Th2 (IL-6 and IL-10) cytokines for any…”
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Increased expression of IGF II mRNA-binding protein 1 mRNA is associated with an advanced clinical stage and poor prognosis in patients with ovarian cancer by Gu, Lijun, Shigemasa, Kazushi, Ohama, Koso

“…The purpose of this study was to examine the expression of IGF II mRNA-binding protein (IMP-1, -2, and -3) mRNA in epithelial ovarian tumors, and to identify…”
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Transmembrane serine protease TADG-15 (ST14 Matriptase MT-SP1): expression and prognostic value in ovarian cancer by Tanimoto, H, Shigemasa, K, Tian, X, Gu, L, Beard, J B, Sawasaki, T, O'Brien, T J

“…Tumour-associated differentially expressed gene-15 (TADG-15/ST14/matriptase/MT-SP1) is a novel member of the transmembrane serine proteases. Previous studies…”
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Skp2 Overexpression Is a Prognostic Factor in Patients with Ovarian Adenocarcinoma by Shigemasa, Kazushi, Gu, Lijun, O'Brien, Timothy J, Ohama, Koso

“…Purpose: The purpose of this study was to examine Skp2 expression in epithelial ovarian tumors and to identify the association of Skp2 expression levels with…”
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The CA 125 gene: a newly discovered extension of the glycosylated N-terminal domain doubles the size of this extracellular superstructure by O'Brien, Timothy J, Beard, John B, Underwood, Lowell J, Shigemasa, Kazushi

“…CA 125 is a well-established marker for patients diagnosed with ovarian carcinoma. It is clearly elaborated in serous cystadenocarcinomas and less likely to be…”
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The stratum corneum chymotryptic enzyme that mediates shedding and desquamation of skin cells is highly overexpressed in ovarian tumor cells by Tanimoto, Hirotoshi, Underwood, Lowell J., Shigemasa, Kazushi, Yan M.S., Yan, Clarke, John, Parmley, Tim H., O'Brien, Timothy J.

“…BACKGROUND Proteases play essential roles in the process of tumor invasion and metastasis. The serine protease stratum corneum chymotryptic enzyme (SCCE) has…”
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