Search Results - "Shigemasa, Chiaki"

Human organic cation transporter ( and ) gene polymorphisms and therapeutic effects of metformin by Shikata, Eriko, Yamamoto, Rei, Takane, Hiroshi, Shigemasa, Chiaki, Ikeda, Tadasu, Otsubo, Kenji, Ieiri, Ichiro

“…Organic cation transporters (OCTs) are responsible for the hepatic and renal transport of metformin. In this study we analyzed variants of OCT1 and OCT2 genes…”
Get full text

A Simple Risk Score to Predict In-Hospital Death of Elderly Patients With Acute Decompensated Heart Failure: Hypoalbuminemia as an Additional Prognostic Factor by Kinugasa, Yoshiharu, Kato, Masahiko, Sugihara, Shinobu, Hirai, Masayuki, Kotani, Kazuhiko, Ishida, Katsunori, Yanagihara, Kiyotaka, Kato, Yosuke, Ogino, Kazuhide, Igawa, Osamu, Hisatome, Ichiro, Shigemasa, Chiaki

“…Background: Risk stratification for elderly patients with acute decompensated heart failure (ADHF) may help clinicians to select the appropriate therapy and…”
Get full text

Appropriate use of nasal continuous positive airway pressure decreases elevated C-reactive protein in patients with obstructive sleep apnea by Ishida, Katsunori, Kato, Masahiko, Kato, Yosuke, Yanagihara, Kiyotaka, Kinugasa, Yoshiharu, Kotani, Kazuhiko, Igawa, Osamu, Hisatome, Ichiro, Shigemasa, Chiaki, Somers, Virend K

“…C-reactive protein (CRP) is an important risk factor for cardiovascular disease. Furthermore, it has been reported that levels of CRP are increased in patients…”
Get more information

Implications of FoxP3-positive and -negative CD4+ CD25+ T cells in Graves’ ophthalmopathy by Matsuzawa, Kazuhiko, Izawa, Shoichiro, Okura, Tsuyoshi, Fujii, Shinya, Matsumoto, Kazuhisa, Shoji, Kyoko, Nakamura, Risa, Sumi, Keisuke, Fujioka, Yohei, Yoshida, Akio, Shigemasa, Chiaki, Kato, Masahiko, Yamamoto, Kazuhiro, Taniguchi, Shin-ichi

“…Graves’ ophthalmopathy (GO) is a common manifestation of Graves’ disease (GD); however, its pathogenesis is not well understood. Recently, the dysregulation of…”
Get full text

Pharmacogenetic determinants of variability in lipid-lowering response to pravastatin therapy by Takane, Hiroshi, Miyata, Masanori, Burioka, Naoto, Shigemasa, Chiaki, Shimizu, Eiji, Otsubo, Kenji, Ieiri, Ichiro

“…Pravastatin is mainly taken up from the circulation into the liver via organic anion-transporting polypeptide 1B1 (SLCO1B1 gene product). We examined the…”
Get full text

Autoantibody against WD repeat domain 1 is a novel serological biomarker for screening of thyroid neoplasia by Izawa, Shoichiro, Okamura, Tomohisa, Matsuzawa, Kazuhiko, Ohkura, Tsuyoshi, Ohkura, Hiroko, Ishiguro, Kiyosuke, Noh, Jaeduk Yoshimura, Kamijo, Keiichi, Yoshida, Akio, Shigemasa, Chiaki, Kato, Masahiko, Yamamoto, Kazuhiro, Taniguchi, Shin-ichi

“…Summary Background Thyroid nodules are common among adults, and accurate diagnosis is critical in for management decisions. Ultrasound and fine needle…”
Get full text

Addition of Losartan to Angiotensin-Converting Enzyme Inhibitors Improves Insulin Resistance in Patients With Chronic Heart Failure Treated Without β-Blockers by Ogino, Kazuhide, Kato, Masahiko, Furuse, Yoshiyuki, Kinugasa, Yoshiharu, Kaetsu, Yasuhiro, Mizuta, Einosuke, Sugihara, Shinobu, Ishida, Katsunori, Yanagihara, Kiyotaka, Hisatome, Ichiro, Shigemasa, Chiaki

“…Background: Angiotensin II and insulin resistance (IR) have clinical implications in the pathophysiology of chronic heart failure (CHF). However, it is still…”
Get full text

Usefulness of three-dimensional echocardiography in assessing right ventricular function in patients with primary pulmonary hypertension by Amaki, Makoto, Nakatani, Satoshi, Kanzaki, Hideaki, Kyotani, Shingo, Nakanishi, Norifumi, Shigemasa, Chiaki, Hisatome, Ichiro, Kitakaze, Masafumi

“…Although right ventricular (RV) function is an important determinant of morbidity and mortality in patients with primary pulmonary hypertension (PPH), there…”
Get full text

Mechanism of Iodide/Chloride Exchange by Pendrin by Yoshida, Akio, Hisatome, Ichiro, Taniguchi, Shinichi, Sasaki, Norihiro, Yamamoto, Yasutaka, Miake, Junichiro, Fukui, Hiroko, Shimizu, Hideki, Okamura, Tomohisa, Okura, Tsuyoshi, Igawa, Osamu, Shigemasa, Chiaki, Green, Eric D, Kohn, Leonard D, Suzuki, Koichi

“…We performed an electrophysiological study to investigate ion transport of pendrin and thereby understand the pathogenesis of Pendred syndrome. Using…”
Get full text

Transient Left Ventricular Apical Ballooning in a Patient With Bicuspid Aortic Valve Created a Left Ventricular Thrombus Leading to Acute Renal Infarction by Sasaki, Norihito, Kinugawa, Toru, Yamawaki, Masahiro, Furuse, Yoshiyuki, Shimoyama, Masaki, Ogino, Kazuhide, Igawa, Osamu, Hisatome, Ichiro, Shigemasa, Chiaki

“…A 44-year-old woman had tako-tsubo-like ventricular dysfunction with chest pain and ST segment elevation on the ECG. Echocardiography revealed a bicuspid…”
Get full text

Allopurinol Improves Cardiac Dysfunction After Ischemia-Reperfusion via Reduction of Oxidative Stress in Isolated Perfused Rat Hearts by Kinugasa, Yoshiharu, Ogino, Kazuhide, Furuse, Yoshiyuki, Shiomi, Tetsuya, Tsutsui, Hiroyuki, Yamamoto, Tetsuya, Igawa, Osamu, Hisatome, Ichiro, Shigemasa, Chiaki

“…It has been reported that the xanthine oxidase inhibitor, allopurinol, has a protective effect on ischemia - reperfusion injury, but the precise mechanism of…”
Get full text

Neurohumoral Profiles in Patients With Hypertrophic Cardiomyopathy: Differences to Hypertensive Left Ventricular Hypertrophy by Ogino, Kazuhide, Ogura, Kazuyoshi, Kinugawa, Toru, Osaki, Shuichi, Kato, Masahiko, Furuse, Yoshiyuki, Kinugasa, Yoshiharu, Tomikura, Yoko, Igawa, Osamu, Hisatome, Ichiro, Shigemasa, Chiaki

“…Background Patients with hypertrophic cardiomyopathy (HCM) or hypertensive heart disease (HHD) have increased concentrations of various neurohumoral factors…”
Get full text

Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca2+ channels in the embryonic heart of mice by Mizuta, Einosuke, Shirai, Manabu, Arakawa, Keita, Hidaka, Kyoko, Miake, Junichiro, Ninomiya, Haruaki, Kato, Masahiko, Shigemasa, Chiaki, Shirayoshi, Yasuaki, Hisatome, Ichiro, Morisaki, Takayuki

“…We investigated the distribution of T-type Ca2+ channel mRNAs in the mouse embryonic heart. Cav3.2, but not Cav3.1, was expressed in the E8.5 embryonic heart…”
Get full text

Status of Uric Acid Management in Hypertensive Subjects by Yamamoto, Yasutaka, Matsubara, Koichi, Igawa, Go, Kaetsu, Yasuhiro, Sugihara, Shinobu, Matsuura, Takashi, Ando, Fumihiro, Sonoyama, Kazuhiko, Hamada, Toshihiro, Ogino, Kazuhide, Igawa, Osamu, Shigemasa, Chiaki, Hisatome, Ichiro

“…Hyperuricemia in hypertensive subjects has been considered one of risk factors of cardiovascular diseases. We investigated the status of uric acid management…”
Get full text

Cretinism by Shigemasa, Chiaki

Get more information

Protective effect of edaravone against hypoxia–reoxygenation injury in rabbit cardiomyocytes by Yamawaki, Masahiro, Sasaki, Norihito, Shimoyama, Masaki, Miake, Junichiro, Ogino, Kazuhide, Igawa, Osamu, Tajima, Fumito, Shigemasa, Chiaki, Hisatome, Ichiro

“…We examined whether edaravone (Eda), a clinically available radical scavenger, directly protects cardiomyocytes from ischemia/reperfusion (I/R) injury, and…”
Get full text

Allopurinol Reduces Neointimal Hyperplasia in the Carotid Artery Ligation Model in Spontaneously Hypertensive Rats by Yamamoto, Yasutaka, Ogino, Kazuhide, Igawa, Go, Matsuura, Takashi, Kaetsu, Yasuhiro, Sugihara, Shinobu, Matsubara, Koichi, Miake, Junichiro, Hamada, Toshihiro, Yoshida, Akio, Igawa, Osamu, Yamamoto, Tetsuya, Shigemasa, Chiaki, Hisatome, Ichiro

“…Uric acid and oxidative stress promote cardiovascular diseases, including atherosclerosis and hypertension. Xanthine oxidase, through which uric acid is…”
Get full text

Plasma Levels of Uridine Correlate With Blood Pressure and Indicators of Myogenic Purine Degradation and Insulin Resistance in Hypertensive Patients by Hamada, Toshihiro, Mizuta, Einosuke, Yanagihara, Kiyotaka, Kaetsu, Yasuhiro, Sugihara, Shinobu, Sonoyama, Kazuhiko, Yamamoto, Yasutaka, Kato, Masahiko, Igawa, Osamu, Shigemasa, Chiaki, Inokuchi, Taku, Yamamoto, Tetsuya, Shimada, Toshio, Ohtahara, Akira, Ninomiya, Haruaki, Hisatome, Ichiro

“…Background The relationship between plasma uridine levels and blood pressure (BP), and indicators of muscular purine degradation and insulin resistance (IR)…”
Get full text

Implications of FoxP3-positive and -negative CD4+ CD25+ T cells in Graves' ophthalmopathy by Kazuhiko Matsuzawa, Shoichiro Izawa, Tsuyoshi Okura, Shinya Fujii, Kazuhisa Matsumoto, Kyoko Shoji, Risa Nakamura, Keisuke Sumi, Yohei Fujioka, Akio Yoshida, Chiaki Shigemasa, Masahiko Kato, Kazuhiro Yamamoto, Shin-ichi Taniguchi

“…Abstract. Graves' ophthalmopathy (GO) is a common manifestation of Graves' disease (GD); however, its pathogenesis is not well understood. Recently, the…”
Get full text

Remote Reperfusion Lung Injury is Associated With AMP Deaminase 3 Activation and Attenuated by Inosine Monophosphate by Li, Peili, Ogino, Kazuhide, Hoshikawa, Yoshiko, Morisaki, Hiroko, Cheng, Jidong, Toyama, Keiko, Morisaki, Takayuki, Hashimoto, Kiyoshi, Ninomiya, Haruaki, Tomikura-Shimoyama, Yoko, Igawa, Osamu, Shigemasa, Chiaki, Hisatome, Ichiro

“…Background Remote reperfusion lung injury occurs in patients with vascular occlusion and surgical procedures. Inosine monophosphate (IMP) produced by adenosine…”
Get full text