Search Results - "Shiflett, Patrick"

Modeling of receptor mimics that inhibit superantigen pathogenesis by Möllhoff, Margit, Zanden, Hannah B. Vander, Shiflett, Patrick R., Gupta, Goutam

“…Staphylococcal enterotoxins SEB and SEC3 and toxic shock syndrome toxin TSST‐1 act as superantigens by overstimulating the human immune system and thereby…”
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Structural Studies on the Hairpins at the 3‘ Untranslated Region of an Anthrax Toxin Gene by Shiflett, Patrick R., Taylor-McCabe, Kirsten J., Michalczyk, Ryszard, Silks, Louis A. “Pete”, Gupta, Goutam

“…Three proteins, namely, protective antigen (PA), edema factor (EF), and lethal factor (LF), encoded by the pX01 plasmid of Bacillus anthracis play a major role…”
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Structure-Based Design of a Bispecific Receptor Mimic That Inhibits T Cell Responses to a Superantigen by Lehnert, Nancy M, Allen, David L, Allen, Beth L, Catasti, Paolo, Shiflett, Patrick R, Chen, Michael, Lehnert, Bruce E, Gupta, Goutam

“…Key surface proteins of pathogens and their toxins bind to the host cell receptors in a manner that is quite different from the way the natural ligands bind to…”
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Rapid targeted gene disruption in Bacillus anthracis by Saldanha, Roland J, Pemberton, Adin, Shiflett, Patrick, Perutka, Jiri, Whitt, Jacob T, Ellington, Andrew, Lambowitz, Alan M, Kramer, Ryan, Taylor, Deborah, Lamkin, Thomas J

“…Anthrax is a zoonotic disease recognized to affect herbivores since Biblical times and has the widest range of susceptible host species of any known pathogen…”
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Design of Chimeric Receptor Mimics with Different TcRVβ Isoforms by Hong-Geller, Elizabeth, Möllhoff, Margit, Shiflett, Patrick R., Gupta, Goutam

“…The Staphylococcus aureus enterotoxins (S.E.) A-I, and toxic-shock syndrome toxin TSST-1 act as superantigens to cause overstimulation of the host immune…”
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Design of chimeric receptor mimics with different TcRVbeta isoforms. Type-specific inhibition of superantigen pathogenesis by Hong-Geller, Elizabeth, Möllhoff, Margit, Shiflett, Patrick R, Gupta, Goutam

“…The Staphylococcus aureus enterotoxins (S.E.) A-I, and toxic-shock syndrome toxin TSST-1 act as superantigens to cause overstimulation of the host immune…”
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Investigation into regulatory elements of Bacillus anthracis pXO1 plasmid pathogenicity island by Shiflett, Patrick

“…Bacillus anthracis is the causative agent for the disease anthrax. Pathogenic genetic elements from B. anthracis lie on two plasmids, pXO1 and pXO2. The pXO2…”
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Modeling of receptor mimics that inhibit superantigen pathogenesis: MODELING OF RECEPTOR MIMICS by Möllhoff, Margit, Zanden, Hannah B. Vander, Shiflett, Patrick R., Gupta, Goutam

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Design of Chimeric Receptor Mimics with Different TcRVβ Isoforms by Elizabeth Hong-Geller, Margit Möllhoff, Patrick R. Shiflett, Goutam Gupta

“…The Staphylococcus aureus enterotoxins (S.E.) A-I, and toxic-shock syndrome toxin TSST-1 act as superantigens to cause overstimulation of the host immune…”
Get full text