Search Results - "Shiels, Brian R"

Sheep as Host Species for Zoonotic Babesia venatorum, United Kingdom by Gray, Alexander, Capewell, Paul, Loney, Colin, Katzer, Frank, Shiels, Brian R, Weir, William

“…Babesia venatorum is an increasingly prominent zoonotic parasite that predominantly infects wild deer. Our molecular examination of Babesia infecting mammals…”
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Susceptibility to disease (tropical theileriosis) is associated with differential expression of host genes that possess motifs recognised by a pathogen DNA binding protein by Larcombe, Stephen D, Capewell, Paul, Jensen, Kirsty, Weir, William, Kinnaird, Jane, Glass, Elizabeth J, Shiels, Brian R

“…Knowledge of factors that influence the outcome of infection are crucial for determining the risk of severe disease and requires the characterisation of…”
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PCR diagnosis of tick-borne pathogens in Maharashtra state, India indicates fitness cost associated with carrier infections is greater for crossbreed than native cattle breeds by Kolte, Sunil W, Larcombe, Stephen D, Jadhao, Suresh G, Magar, Swapnil P, Warthi, Ganesh, Kurkure, Nitin V, Glass, Elizabeth J, Shiels, Brian R

“…Tick-borne pathogens (TBP) are responsible for significant economic losses to cattle production, globally. This is particularly true in countries like India…”
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A Bovine Lymphosarcoma Cell Line Infected with Theileria annulata Exhibits an Irreversible Reconfiguration of Host Cell Gene Expression by Kinnaird, Jane H, Weir, William, Durrani, Zeeshan, Pillai, Sreerekha S, Baird, Margaret, Shiels, Brian R

“…Theileria annulata, an intracellular parasite of bovine lymphoid cells, induces substantial phenotypic alterations to its host cell including continuous…”
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Evolution and diversity of secretome genes in the apicomplexan parasite Theileria annulata by Weir, William, Karagenç, Tülin, Baird, Margaret, Tait, Andy, Shiels, Brian R

“…Little is known about how apicomplexan parasites have evolved to infect different host species and cell types. Theileria annulata and Theileria parva invade…”
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TGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibility by Chaussepied, Marie, Janski, Natacha, Baumgartner, Martin, Lizundia, Regina, Jensen, Kirsty, Weir, William, Shiels, Brian R, Weitzman, Jonathan B, Glass, Elizabeth J, Werling, Dirk, Langsley, Gordon

“…Theileria parasites invade and transform bovine leukocytes causing either East Coast fever (T. parva), or tropical theileriosis (T. annulata). Susceptible…”
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Wild deer in the United Kingdom are a potential reservoir for the livestock parasite Babesia divergens by Gray, Alexander, Capewell, Paul, Zadoks, Ruth, Taggart, Mark A., French, Andrew S., Katzer, Frank, Shiels, Brian R., Weir, William

“…Redwater fever is an economically important disease of cattle in the United Kingdom caused by the protozoan parasite Babesia divergens. Control efforts are…”
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Extensive Polymorphism and Evidence of Immune Selection in a Highly Dominant Antigen Recognized by Bovine CD8 T Cells Specific for Theileria annulata by MacHugh, Niall D, Weir, William, Burrells, Alison, Lizundia, Regina, Graham, Simon P, Taracha, Evans L, Shiels, Brian R, Langsley, Gordon, Morrison, W. Ivan

“…Although parasite strain-restricted CD8 T cell responses have been described for several protozoa, the precise role of antigenic variability in immunity is…”
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Fatal cases of Theileria annulata infection in calves in Portugal associated with neoplastic-like lymphoid cell proliferation by Branco, Sandra, Universidade de Evora, Polo da Mitra, Evora, Portugal, Orvalho, Joao, University of California, Veterinary Medical Center, San Diego, USA, Leitao, Alexandre, Avenida da Universidade Tecnica, Lisboa, Portugal, Pereira, Isadora, Avenida da Universidade Tecnica, Lisboa, Portugal, Malta, Manuel, Vet+ Servicos Veterinarios Lda., Mentemor-o-Novo, Portugal, Mariano, Isabel, Cooperativa Agricola de Compra e Venda de Mentemor-o-Novo, CRL (COPRAPEC), Montemor-o-Novo, Portugal, Carvalho, Tania, Centro de Investigacao em Patobiologia Molecular, Instituto Portugues de Oncologia, Lisboa, Portugal, Baptista, Rui, Laboratorio Nacional de Investigacao Veterinaria, Lisboa, Portugal, Shiels, Brian R., University of Glasgow, Bearsden Road, Glasgow, Scotland, Peleteiro, Maria C., Avenida da Universidade Tecnica, Lisboa, Portugal

“…This study was carried out to investigate fifteen cases of acute lethal infection of calves (less-than or equal to 4 months of age) by the protozoan parasite…”
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Investigating the presence of equine piroplasmosis in Ireland by Coultous, Robert M, Leadon, Desmond P, Shiels, Brian R, Sutton, David, Weir, William

“…BackgroundEquine piroplasmosis (EP) is a notifiable disease in Ireland and a significant concern to domestic and international equine industries. Information…”
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Equine piroplasmosis status in the UK: an assessment of laboratory diagnostic submissions and techniques by Coultous, Robert M, Phipps, Paul, Dalley, Charlie, Lewis, Jane, Hammond, Toni-Ann, Shiels, Brian R, Weir, William, Sutton, David G M

“…Equine piroplasmosis (EP) has historically been of minor concern to UK equine practitioners, primarily due to a lack of competent tick vectors. However,…”
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Characterization of a polymorphic Theileria annulata surface protein ( TaSP) closely related to PIM of Theileria parva: implications for use in diagnostic tests and subunit vaccines by Schnittger, Leonhard, Katzer, Frank, Biermann, Reinhild, Shayan, Parviz, Boguslawski, Kati, McKellar, Sue, Beyer, Doreen, Shiels, Brian R., Ahmed, Jabbar S.

“…Theileria annulata is a tick-transmitted protozoan that causes tropical theileriosis, an often fatal leukoproliferative disorder of cattle. To characterize and…”
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A Theileria annulata DNA Binding Protein Localized to the Host Cell Nucleus Alters the Phenotype of a Bovine Macrophage Cell Line by Shiels, Brian R, McKellar, Sue, Katzer, Frank, Lyons, Kim, Kinnaird, Jane, Ward, Chris, Wastling, Jonathan M, Swan, David

“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Analysis of Theileria equi diversity in The Gambia using a novel genotyping method by Coultous, Robert M., McDonald, Michael, Raftery, Alexandra G., Shiels, Brian R., Sutton, David G. M., Weir, William

“…Theileria equi, one of the primary pathogens causing equine piroplasmosis, has previously been sub‐classified into a number of clades on the basis of 18S SSU…”
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Characterization of HSP90 isoforms in transformed bovine leukocytes infected with Theileria annulata by Kinnaird, Jane H., Singh, Meetali, Gillan, Victoria, Weir, William, Calder, Ewen D. D., Hostettler, Isabel, Tatu, Utpal, Devaney, Eileen, Shiels, Brian R.

“…Summary HSP90 chaperones are essential regulators of cellular function, as they ensure the appropriate conformation of multiple key client proteins. Four HSP90…”
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Molecular confirmation of Sarcocystis fayeri in a donkey by Coultous, Robert M., Raftery, Alexandra G., Shiels, Brian R., Sutton, David G.M., Weir, William

“…•Molecular confirmation of Sarcocystis fayeri in a donkey for the first time.•Phylogenetic analysis of sequence demonstrates placement in S. fayeri clade.•The…”
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Generation of a mosaic pattern of diversity in the major merozoite-piroplasm surface antigen of Theileria annulata by Gubbels, Marc-Jan, Katzer, Frank, Hide, Geoff, Jongejan, Frans, Shiels, Brian R

“…The polypeptide Tams1 is an immunodominant major merozoite piroplasm surface antigen of the protozoan parasite Theileria annulata. Generation and selection of…”
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Infection of bovine cells by the protozoan parasite Theileria annulata modulates expression of the ISGylation system by Oura, Chris A. L., McKellar, Sue, Swan, David G., Okan, Emel, Shiels, Brian R.

“…Summary The apicomplexan parasite, Theileria annulata, dedifferentiates and induces continuous division of infected bovine myeloid cells. Re‐expression of…”
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TashHN, a Theileria annulata encoded protein transported to the host nucleus displays an association with attenuation of parasite differentiation by Swan, David G., Stadler, Laura, Okan, Emel, Hoffs, Michael, Katzer, Frank, Kinnaird, Jane, McKellar, Sue, Shiels, Brian R.

“…Summary The intracellular apicomplexan parasite, Theileria annulata, manipulates its bovine host cell by over‐riding the cells natural apoptotic response and…”
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Characterisation of a cluster of genes encoding Theileria annulata AT hook DNA-binding proteins and evidence for localisation to the host cell nucleus by Swan, D G, Stern, R, McKellar, S, Phillips, K, Oura, C A, Karagenc, T I, Stadler, L, Shiels, B R

“…Infection of bovine leukocytes by the apicomplexan parasite Theileria annulata results in alteration of host cell gene expression and stimulation of host cell…”
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