Search Results - "Shields, Michelle T."

Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G1 phase by LIN, D, SHIELDS, M. T, ULLRICH, S. J, APPELLA, E, MERCER, W. E

“…Conditional expression of wild-type (wt) p53 protein in a glioblastoma tumor cell line has been shown to be growth inhibitory. We have now more precisely…”
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Negative Growth Regulation in a Glioblastoma Tumor Cell Line that Conditionally Expresses Human Wild-Type p53 by Mercer, W. Edward, Shields, Michelle T., Amin, Mamta, Sauve, Gordon J., Appella, Ettore, Romano, Joseph W., Ullrich, Stephen J.

“…To investigate the effect that human wild-type p53 (wt-p53) expression has on cell proliferation we constructed a recombinant plasmid, pM47, in which wt-p53…”
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Growth Suppression Induced by Wild-Type p53 Protein is Accompanied by Selective Down-Regulation of Proliferating-Cell Nuclear Antigen Expression by Mercer, W. Edward, Shields, Michelle T., Lin, David, Appella, Ettore, Ullrich, Stephen J.

“…The p53 gene is a frequent target of mutation in a wide variety of human cancers. Previously, it was reported that conditional expression of wild-type p53…”
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Mutation of the serine 15 phosphorylation site of human p53 reduces the ability of p53 to inhibit cell cycle progression by Fiscella, M, Ullrich, S J, Zambrano, N, Shields, M T, Lin, D, Lees-Miller, S P, Anderson, C W, Mercer, W E, Appella, E

“…Overexpression of wild-type p53 prevents cells from entering the S phase of the cell cycle. The amino-terminal transactivation region of p53 is phosphorylated…”
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Growth arrest induced by wild-type p53 protein blocks cells prior to or near the restriction point in late G(1) phase by Lin, David, Shields, Michelle T, Ullrich, Stephen J, Appella, Ettore, Mercer, W Edward

“…Conditional expression of wild-type nuclear phosphoprotein p53 in a glioblastoma tumor cell line has been shown to be growth inhibitory. The results of a study…”
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Growth Arrest Induced by Wild-Type p53 Protein Blocks Cells Prior to or Near the Restriction Point in Late G1Phase by Lin, David, Shields, Michelle T., Ullrich, Stephen J., Appella, Ettore, Mercer, W. Edward

“…Conditional expression of wild-type (wt) p53 protein in a glioblastoma tumor cell line has been shown to be growth inhibitory. We have now more precisely…”
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Cell cycle effects of microinjected antisense oligodeoxynucleotides to p34cdc2 kinase by Mercer, W E, Ullrich, S J, Shields, M T, Lin, D, Alder, H

“…In this study the effect of antisense oligomers targeted against the mRNA transcripts of p34cdc2 kinase on G1 progression into S-phase was examined. For this…”
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Growth factor regulated expression of poly(A)+ binding protein messenger RNA by Mercer, W E, Jaskulski, D, Shields, M T

“…A 72,000 mol wt protein designated PABP binds to the poly(A)+ track of messenger RNAs with high affinity and has been suggested to play an important role in…”
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