Search Results - "Shichinohe, Hideo"

Clinical Trials of Stem Cell Therapy for Cerebral Ischemic Stroke by Kawabori, Masahito, Shichinohe, Hideo, Kuroda, Satoshi, Houkin, Kiyohiro

“…Despite recent developments in innovative treatment strategies, stroke remains one of the leading causes of death and disability worldwide. Stem cell therapy…”
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Therapeutic effects of human multilineage-differentiating stress enduring (MUSE) cell transplantation into infarct brain of mice by Yamauchi, Tomohiro, Kuroda, Yasumasa, Morita, Takahiro, Shichinohe, Hideo, Houkin, Kiyohiro, Dezawa, Mari, Kuroda, Satoshi

“…Bone marrow stromal cells (BMSCs) are heterogeneous and their therapeutic effect is pleiotropic. Multilineage-differentiating stress enduring (Muse) cells are…”
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Chronic Ischemia Alters Brain Microstructural Integrity and Cognitive Performance in Adult Moyamoya Disease by Kazumata, Ken, Tha, Khin Khin, Narita, Hisashi, Kusumi, Ichiro, Shichinohe, Hideo, Ito, Masaki, Nakayama, Naoki, Houkin, Kiyohiro

“…BACKGROUND AND PURPOSE—The mechanisms underlying frontal lobe dysfunction in moyamoya disease (MMD) are unknown. We aimed to determine whether chronic ischemia…”
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Cell Therapy for Stroke: Review of Previous Clinical Trials and Introduction of Our New Trials by SHICHINOHE, Hideo, HOUKIN, Kiyohiro

“…Stroke is still a leading cause of death and disability, and despite intensive research, few treatment options exist. A recent breakthrough in cell therapy is…”
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Cellular Functions and Gene and Protein Expression Profiles in Endothelial Cells Derived from Moyamoya Disease-Specific iPS Cells by Hamauchi, Shuji, Shichinohe, Hideo, Uchino, Haruto, Yamaguchi, Shigeru, Nakayama, Naoki, Kazumata, Ken, Osanai, Toshiya, Abumiya, Takeo, Houkin, Kiyohiro, Era, Takumi

“…Moyamoya disease (MMD) is a slow, progressive steno-occlusive disease, arising in the terminal portions of the cerebral internal carotid artery. However, the…”
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Responses of Immune Organs after Cerebral Ischemic Stroke by Tan, Chengbo, Wang, Zifeng, Zheng, Miao, Zhao, Songji, Shichinohe, Hideo, Houkin, Kiyohiro

“…Background: Stroke is a leading cause of death and disability worldwide. Recently, secondary damage to the brain has been hypothesized as a key aggravating…”
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Application of cell sheet technology to bone marrow stromal cell transplantation for rat brain infarct by Ito, Masaki, Shichinohe, Hideo, Houkin, Kiyohiro, Kuroda, Satoshi

“…Bone marrow stromal cells (BMSC) transplantation enhances functional recovery after cerebral infarct, but the optimal delivery route is undetermined. This…”
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Transarterial Regional Brain Hypothermia Inhibits Acute Aquaporin-4 Surge and Sequential Microvascular Events in Ischemia/Reperfusion Injury by Kurisu, Kota, Abumiya, Takeo, Nakamura, Hideki, Shimbo, Daisuke, Shichinohe, Hideo, Nakayama, Naoki, Kazumata, Ken, Shimizu, Hiroshi, Houkin, Kiyohiro

“…Abstract BACKGROUND Although transarterial regional hypothermia is an attractive alternative to general hypothermia, its efficacy and underlying mechanisms…”
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Research on advanced intervention using novel bone marrOW stem cell (RAINBOW): a study protocol for a phase I, open-label, uncontrolled, dose-response trial of autologous bone marrow stromal cell transplantation in patients with acute ischemic stroke by Shichinohe, Hideo, Kawabori, Masahito, Iijima, Hiroaki, Teramoto, Tuyoshi, Abumiya, Takeo, Nakayama, Naoki, Kazumata, Ken, Terasaka, Shunsuke, Arato, Teruyo, Houkin, Kiyohiro

“…Stroke is a leading cause of death and disability, and despite intensive research, few treatment options exist. However, a recent breakthrough in cell therapy…”
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Review of Past Research and Current Concepts on the Etiology of Moyamoya Disease by HOUKIN, Kiyohiro, ITO, Masaki, SUGIYAMA, Taku, SHICHINOHE, Hideo, NAKAYAMA, Naoki, KAZUMATA, Ken, KURODA, Satoshi

“…Research on moyamoya disease has progressed remarkably in the past several decades. Indeed, many new facts concerning the epidemiology of the disease have been…”
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Bone Marrow Stromal Cells Rescue Ischemic Brain by Trophic Effects and Phenotypic Change Toward Neural Cells by Shichinohe, Hideo, Ishihara, Takeshi, Takahashi, Koji, Tanaka, Yoshikazu, Miyamoto, Michiyuki, Yamauchi, Tomohiro, Saito, Hisayasu, Takemoto, Hiroshi, Houkin, Kiyohiro, Kuroda, Satoshi

“…Background. Transplantation of bone marrow stromal cells (BMSCs) may contribute to functional recovery after stroke. This study was designed to clarify their…”
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Topographic changes in cerebral blood flow and reduced white matter integrity in the first 2 weeks following revascularization surgery in adult moyamoya disease by Kazumata, Ken, Tha, Khin Khin, Uchino, Haruto, Shiga, Tohru, Shichinohe, Hideo, Ito, Masaki, Nakayama, Naoki, Abumiya, Takeo

“…OBJECTIVE After revascularization surgery, hyperperfusion and ischemia are associated with morbidity and mortality in adult moyamoya disease (MMD). However,…”
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Bone marrow stromal cells protect and repair damaged neurons through multiple mechanisms by Hokari, Masaaki, Kuroda, Satoshi, Shichinohe, Hideo, Yano, Shunsuke, Hida, Kazutoshi, Iwasaki, Yoshinobu

“…A surprising shortage of information surrounds the mechanism by which bone marrow stromal cells (BMSC) restore lost neurologic functions when transplanted into…”
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Evaluation of Novel Stereotactic Cannula for Stem Cell Transplantation against Central Nervous System Disease by Shichinohe, Hideo, Kitta, Shinri, Tanimori, Aki, Kawabori, Masahito, Houkin, Kiyohiro

“…Cell therapy for central nervous system (CNS) disorders is beginning to prove its safety and efficiency. Intraparenchymal transplantation can be an option for…”
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Post-ischemic intra-arterial infusion of liposome-encapsulated hemoglobin can reduce ischemia reperfusion injury by Shimbo, Daisuke, Abumiya, Takeo, Shichinohe, Hideo, Nakayama, Naoki, Kazumata, Ken, Houkin, Kiyohiro

“…Abstract Despite successful revascularization, reperfusion after prolonged ischemia causes ischemia reperfusion (I/R) injury. Recruitment and activation of…”
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Timing and cell dose determine therapeutic effects of bone marrow stromal cell transplantation in rat model of cerebral infarct by Kawabori, Masahito, Kuroda, Satoshi, Ito, Masaki, Shichinohe, Hideo, Houkin, Kiyohiro, Kuge, Yuji, Tamaki, Nagara

“…Stereotactic transplantation of bone marrow stromal cells (BMSCs) enables efficient delivery to the infarct brain. This study was aimed to assess its optimal…”
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Responses of immune organs following cerebral ischemic stroke by Tan, Chengbo, Wang, Zifeng, Zheng, Miao, Zhao, Songji, Shichinohe, Hideo, Houkin, Kiyohiro

“…Background: Stroke is a leading cause of death and disability worldwide. Recently, brain secondary damage has been hypothesized to be a key aggravating element…”
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Neuroprotective effects of cilostazol are mediated by multiple mechanisms in a mouse model of permanent focal ischemia by Shichinohe, Hideo, Tan, Chengbo, Abumiya, Takeo, Nakayama, Naoki, Kazumata, Ken, Hokari, Masaaki, Houkin, Kiyohiro, Kuroda, Satoshi

“…Abstract The phosphodiesterase (PDE) 3 inhibitor cilostazol, used as an anti-platelet drug, reportedly can also ameliorate ischemic brain injury. Here, we…”
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Intracerebral Transplantation of Mesenchymal Stromal Cell Compounded with Recombinant Peptide Scaffold against Chronic Intracerebral Hemorrhage Model by Takamiya, Soichiro, Kawabori, Masahito, Kitahashi, Tsukasa, Nakamura, Kentaro, Mizuno, Yuki, Yasui, Hironobu, Kuge, Yuji, Tanimori, Aki, Takamatsu, Yasuyuki, Yuyama, Kohei, Shichinohe, Hideo, Fujimura, Miki

“…Background. Due to the lack of effective therapies, stem cell transplantation is an anticipated treatment for chronic intracerebral hemorrhage (ICH), and…”
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Ultrasound-guided Femoral Artery Access for Minimally Invasive Neuro-intervention and Risk Factors for Access Site Hematoma by KURISU, Kota, OSANAI, Toshiya, KAZUMATA, Ken, NAKAYAMA, Naoki, ABUMIYA, Takeo, SHICHINOHE, Hideo, SHIMODA, Yusuke, HOUKIN, Kiyohiro

“…Although ultrasound (US) guidance for venous access is becoming the “standard of care” for preventing access site complications, its feasibility for arterial…”
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